Refining, reducing and replacing non-model amphibian experiments on amphibian infectious diseases.

Lead Research Organisation: Royal Veterinary College
Department Name: Pathobiology and Population Sciences

Abstract

This project will (1: refinement) establish valid indicators for use in welfare monitoring and implementation of appropriate humane end points; (2: reduction) explore the utility of skin tissue expants for studying infection dynamics and growth rates of ranaviruses and chytridiomycete fungi, and; (3: replacement) cell cultures for investigating ranavirus growth rates and the development or 'organ on a chip' for studying ranaviruses and chytridiomycete fungi.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
NC/R001790/1 16/11/2017 30/06/2022
2096870 Studentship NC/R001790/1 01/10/2018 30/09/2021 Lola Michelle Brookes