Inorganic nanoparticles for cancer therapy

Lead Research Organisation: Imperial College London
Department Name: Materials

Abstract

Chemotherapy drugs are known to have widespread side effects. Zinc oxide nanowires have been shown to kill cancer cells without killing healthy equivalents but they degrade too fast in blood. Here, we develop silica nanoparticles containing zinc that can deliver zinc inside cells. The project involves nanoparticle synthesis and characterization, to optimize the zinc delivery. Uptake of the nanoparticles into cells is being investigated, including identifying toxicity ranges and doses in which the nanoparticles can kill breast and bone cancer cells without killing the healthy equivalents.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/N509486/1 01/10/2016 30/09/2021
2275454 Studentship EP/N509486/1 09/10/2017 30/04/2021 Taneisha McFarlane