Heterocycle Synthesis in Flow: Diverse Screening Collections via Continuous Flow Processes

Lead Research Organisation: Imperial College London
Department Name: Department of Chemical Engineering

Abstract

This work will develop a reliable and efficient process for heterocycle synthesis in continuous flow, to generate compounds appropriate as fragments or lead-like compounds for screening against biological targets. A variety of activated methylene compounds and halo-alcohols with varied substitution and chain length will be combined through the same process.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/N509486/1 01/10/2016 31/03/2022
2288177 Studentship EP/N509486/1 30/10/2017 30/04/2021 Sebastian Green