Microphysiological models for the assessment of pulmonary concentration of inhaled aerosols
Lead Research Organisation:
University of Hertfordshire
Department Name: School of Life and Medical Sciences
Abstract
TBC- Year 1 CDT student.
Outline description (to be updated in summer 2021):
There are significant gaps in our understanding of the links between aerosol deposition sites, binding to lung tissue and the time course of local drug concentrations during inhaled therapy. This project will combine emerging microfluidic, lung-on-a-chip technologies with liquid chromatography-mass spectrometry bioanalysis to explore the 'holy grail' of in-lung pharmacokinetics.
Outline description (to be updated in summer 2021):
There are significant gaps in our understanding of the links between aerosol deposition sites, binding to lung tissue and the time course of local drug concentrations during inhaled therapy. This project will combine emerging microfluidic, lung-on-a-chip technologies with liquid chromatography-mass spectrometry bioanalysis to explore the 'holy grail' of in-lung pharmacokinetics.
People |
ORCID iD |
| Darragh Murnane (Primary Supervisor) | |
| Caterina Fantuzzi (Student) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| EP/S023593/1 | 01/04/2019 | 30/09/2027 | |||
| 2446873 | Studentship | EP/S023593/1 | 01/11/2020 | 31/10/2024 | Caterina Fantuzzi |