Roles of post-translational modifications in neurodegenerative protein aggregation

Lead Research Organisation: Imperial College London
Department Name: Dept of Chemistry

Abstract

Identifying and characterising PTMs, which are able to redirect, delay, or accelerate the formation of amyloids of the protein alpha-synuclein, which are linked to Parkinson's disease and other forms of dementia. During her project, she will use a highly multidisciplinary approach, involving chemical biology for generating PTM-amyloids, antibody production techniques, and biophysical structural and functional analysis of proteins.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/S023518/1 01/10/2019 31/03/2028
2453426 Studentship EP/S023518/1 03/10/2020 30/09/2023 Rebecca Jade Thrush