Developing new tools to investigate complex redox-active proteins

Lead Research Organisation: Imperial College London
Department Name: Dept of Chemistry

Abstract

I intend to investigate the elusive mechanism of respiratory enzyme complex I, a protein that is essential for ATP synthesis and whose malfunction is associated with ageing and numerous neurodegenerative disorders including Parkinson's disease. In order to acquire cutting-edge insight into large metalloenzymes such as the complex I, a novel technique developed by Roessler lab will be applied and developed further, which involves the combination of electron paramagnetic resonance (EPR) spectroscopy and protein film electrochemistry (PFE).

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/S023518/1 01/10/2019 31/03/2028
2453516 Studentship EP/S023518/1 20/10/2020 19/10/2023 Fang Fang