5' modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage. (2020)
Attributed to:
A mechanistic framework for DNA recognition and cleavage by Type V CRISPR-Cas effector nucleases
funded by
BBSRC
Abstract
No abstract provided
Bibliographic Information
Digital Object Identifier: http://dx.doi.org/10.1093/nar/gkaa477
PubMed Identifier: 32496535
Publication URI: http://europepmc.org/abstract/MED/32496535
Type: Journal Article/Review
Volume: 48
Parent Publication: Nucleic acids research
Issue: 12
ISSN: 0305-1048