Molecular assembly using gold catalysis
Lead Research Organisation:
University of St Andrews
Department Name: Chemistry
Abstract
The development of catalytic methods leading to little or no waste is an area of crucial importance in terms of energy and materials economy. The present proposal presents strategies to assemble complex molecular architectures or value-added compounds using simply synthesized organogold complexes. The proposal adopts a two-prong approach. On the one side the design and synthesis of organogold catalysts are proposed and on the other some of the catalysts already synthesized by our group and the novel ones are proposed to enable important chemical transformations. These range from hydration reactions to tandem reactions leading to multiple bond formations in a single step. The aim of the proposal is to develop useful synthetic tools, readily usable by synthetic chemists permitting facile protocols enabling the synthesis of complex molecular assemblies.
Organisations
People |
ORCID iD |
| Steven Nolan (Principal Investigator) |
Publications
Fortman GC
(2010)
A versatile gold synthon for acetylene C-H bond activation.
in Dalton transactions (Cambridge, England : 2003)
Ramón RS
(2010)
Au/Ag-cocatalyzed aldoximes to amides rearrangement under solvent- and acid-free conditions.
in The Journal of organic chemistry
Hashmi A
(2011)
Selectivity Switch in the Synthesis of Vinylgold(I) Intermediates
in Organometallics
Nun P
(2011)
Efficient silver-free gold(I)-catalyzed hydration of alkynes at low catalyst loading
in Journal of Organometallic Chemistry
Boogaerts II
(2011)
Direct C-H carboxylation with complexes of the coinage metals.
in Chemical communications (Cambridge, England)
Patrick SR
(2011)
The role of silver additives in gold-mediated C-H functionalisation.
in Beilstein journal of organic chemistry
Dupuy S
(2011)
Decarboxylation of aromatic carboxylic acids by gold(I)-N-heterocyclic carbene (NHC) complexes.
in Chemical communications (Cambridge, England)
Konkolewicz D
(2011)
Luminescent Hyperbranched Polymers: Combining Thiol-Yne Chemistry with Gold-Mediated C-H Bond Activation
in Organometallics
Gómez-Suárez A
(2011)
Influence of a Very Bulky N- Heterocyclic Carbene in Gold-Mediated Catalysis
in Organometallics
Nolan SP
(2011)
The development and catalytic uses of N-heterocyclic carbene gold complexes.
in Accounts of chemical research