Purification of Adeno-Associated Virus (AAV) by continuous Chromatography
Lead Participant:
COBRA BIOLOGICS LIMITED
Abstract
The project aims to increase yields of Adeno-Associated Viral (AAV) vectors for human gene therapy studies through the improved purification processes and through the adoption of continuous chromatography approaches. The project aims to develop purification processes with improved yields and robustness that can be readily scaled to those required for in-market requirements at a reduced cost of goods than is currently being achieved for these vectors, addressing the critical needs to increase the supply and costs of these medicines.
Lead Participant | Project Cost | Grant Offer |
---|---|---|
COBRA BIOLOGICS LIMITED | £601,675 | £ 361,005 |
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Participant |
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INNOVATE UK | ||
PALL EUROPE LIMITED | £447,765 | £ 223,882 |
COBRA BIOLOGICS LIMITED | ||
CELL THERAPY CATAPULT LIMITED | £449,450 | £ 449,450 |
CELL THERAPY CATAPULT SERVICES LIMITED |
People |
ORCID iD |
Antony Hitchcock (Project Manager) |