Nickel Catalysis: New Insights from Mechanistic Studies
Lead Research Organisation:
University of Strathclyde
Department Name: Pure and Applied Chemistry
Abstract
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People |
ORCID iD |
David Nelson (Primary Supervisor) | |
Alasdair Cooper (Student) |
Publications

Cooper A. K.
(2020)
Nickel versus Palladium in Cross-Coupling Catalysis: On the Role of Substrate Coordination to Zerovalent Metal Complexes
in Synthesis
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/P51066X/1 | 30/09/2016 | 29/09/2021 | |||
1792766 | Studentship | EP/P51066X/1 | 30/09/2016 | 31/12/2020 | Alasdair Cooper |
Description | So far, we have shown that nickel -based catalysts are much more susceptible to various structural (functional) groups present when carrying out carbon-carbon bond formation reactions. This effect can be used to achieve considerably high selectivity for such reactions when using these catalysts (an effect which is still present when using the much more industry-favoured palladium catalysts, but not as pronounced) which could impact the way in which various agrochemicals (herbicides, fungicides etc.) and pharmaceuticals (prescription drugs etc.) are synthesised. Some data on the rate of these kinds of reactions has been gathered which gives useful insight into how to make these kinds of reactions more efficient and (therefore) more environmentally friendly. |
Exploitation Route | We plan to investigate the observed effects more thoroughly, with a view to expanding the applicability in order to make these catalysts more attractive to industry-based processes, as nickel is more abundant than palladium. |
Sectors | Agriculture Food and Drink Chemicals Education Pharmaceuticals and Medical Biotechnology |
Description | EPSRC NPIF Innovation Placement |
Amount | £1,550 (GBP) |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2019 |
End | 09/2019 |