Nickel Catalysis: New Insights from Mechanistic Studies

Lead Research Organisation: University of Strathclyde
Department Name: Pure and Applied Chemistry

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/P51066X/1 30/09/2016 29/09/2021
1792766 Studentship EP/P51066X/1 30/09/2016 31/12/2020 Alasdair Cooper
 
Description So far, we have shown that nickel -based catalysts are much more susceptible to various structural (functional) groups present when carrying out carbon-carbon bond formation reactions. This effect can be used to achieve considerably high selectivity for such reactions when using these catalysts (an effect which is still present when using the much more industry-favoured palladium catalysts, but not as pronounced) which could impact the way in which various agrochemicals (herbicides, fungicides etc.) and pharmaceuticals (prescription drugs etc.) are synthesised.

Some data on the rate of these kinds of reactions has been gathered which gives useful insight into how to make these kinds of reactions more efficient and (therefore) more environmentally friendly.
Exploitation Route We plan to investigate the observed effects more thoroughly, with a view to expanding the applicability in order to make these catalysts more attractive to industry-based processes, as nickel is more abundant than palladium.
Sectors Agriculture

Food and Drink

Chemicals

Education

Pharmaceuticals and Medical Biotechnology
 
Description EPSRC NPIF Innovation Placement
Amount £1,550 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2019 
End 09/2019