Using human IPS cells to identify genetic variants that inluence cellular differentiation

Lead Research Organisation: King's College London
Department Name: Genetics and Molecular Medicine

Abstract

The project will contribute to the Wellcome Trust/MRC-funded Human Pluripotent Stem Call initiative which is using human iPS cells from healthy individuals to understand the genetic basis of inter-individual variability of cellular functions. By applying cell-based assays to distinguish causative from correlative genetic variants in healthy and diseased individuals we aim to develop an in vitro approach to precision medicine.

Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/N013700/1 01/10/2016 30/09/2025
1847533 Studentship MR/N013700/1 26/09/2016 31/07/2021 Alice Vickers
 
Description Presentation of research to sixth form students 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Event organised by Institute for Research in Schools - presented my research project to ~200 sixth form students and participated in Q&A session with them at the Wellcome Trust (21st November 2017).
Year(s) Of Engagement Activity 2017
 
Description Stem cell embroidery workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Organised a series of stem cell embroidery workshops called "Stitch and Stem". Images of stem cells and stem cell structures which have been generated by researchers in our department are used as embroidery templates and attendees are taught about stem cells while learning a transferrable skill.
Year(s) Of Engagement Activity 2018