Optimising sonodynamic therapy for the treatment of prostate cancer
Lead Research Organisation:
University College London
Department Name: Surgical Biotechnology
Abstract
Aim: The main aim of the project is to develop and establish the efficacy of porphyrin-carrying nanoparticles for enhancing the effect of SDT in the treatment of prostate tumours.
Key Hypothesis: Firstly, that porphyrin-containing nanoparticles that are degraded in tumour-like conditions have improved prostate tumour accumulation and tumour diffusion profiles. Secondly, that porphyrin-containing nanoparticles with improved prostate tumour accumulation profile can improve the antitumour efficacy of SDT and lead to the optimisation of this therapeutic modality for prostate cancer treatment.
Key Hypothesis: Firstly, that porphyrin-containing nanoparticles that are degraded in tumour-like conditions have improved prostate tumour accumulation and tumour diffusion profiles. Secondly, that porphyrin-containing nanoparticles with improved prostate tumour accumulation profile can improve the antitumour efficacy of SDT and lead to the optimisation of this therapeutic modality for prostate cancer treatment.
Organisations
People |
ORCID iD |
Nikolitsa Nomikou (Primary Supervisor) | |
Hamzah Masood (Student) |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/R513143/1 | 01/10/2018 | 30/09/2023 | |||
2270591 | Studentship | EP/R513143/1 | 30/09/2019 | 29/12/2023 | Hamzah Masood |