Sphingolipid biosynthesis in man and microbes
Lead Research Organisation:
University of Edinburgh
Department Name: Sch of Chemistry
Abstract
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Organisations
People |
ORCID iD |
| Dominic Campopiano (Principal Investigator) |
Publications
Beattie AE
(2013)
The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutations.
in BioMed research international
Lowther J
(2012)
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
in Biochemical Society transactions
Lowther J
(2011)
Role of a conserved arginine residue during catalysis in serine palmitoyltransferase.
in FEBS letters
Wadsworth JM
(2013)
The chemical basis of serine palmitoyltransferase inhibition by myriocin.
in Journal of the American Chemical Society
| Description | We used this travel grant to send scientists from my group to a collaborating lab in Bethesda USA - Prof. Teresa Dunn. We developed structural and functional studies of the enzyme target. We also used this grant to collaborate and publish with a leading Japanese group. |
| Exploitation Route | We also used the funding to attend Deater Family meetings - a family affected by a rare neuropathic disease HSN1. |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Description | This was a travel grant that allowed me to visit my USA collaborators in Washington DC and attend the key scientific meetings in the sphingolipid field. |
| First Year Of Impact | 2008 |
| Sector | Pharmaceuticals and Medical Biotechnology |
| Impact Types | Societal |