China:UK collaborative exchange: Microbes, metabolism and ageing
Lead Research Organisation:
Durham University
Department Name: Biological and Biomedical Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Zhang C
(2015)
Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children.
in EBioMedicine
| Description | 1. We have discovered that C. elegans can be used to understand bacteria isolated from humans and associated with obesity. 2. We have established a C. elegans facility at Shanghai Jiao Tong University and trained members of the Zhao lab to work with C. elegans. 3. We have generated preliminary data for further grants applications and papers. 4. We have gained interest and support from a Chinese manufacturer of nutrition products. |
| Exploitation Route | We will develop our findings so that other can design interventions to tackle obesity by targeting gut microbes. |
| Sectors | Agriculture, Food and Drink,Healthcare |
| Description | The findings have been used to encourage a company in China to fund further research. |
| First Year Of Impact | 2014 |
| Sector | Agriculture, Food and Drink |
| Impact Types | Economic |
| Description | UK:China Partnership: Microbes, metabolism and ageing |
| Organisation | Shanghai Jiao Tong University |
| Country | China |
| Sector | Academic/University |
| PI Contribution | We have travelled to China to present our work, discuss ideas, set up a C. elegans facility and train members of our partners team. We organised an international workshop in Durham and invited our partners. |
| Collaborator Contribution | Our partners have visited the UK to present and discuss work. They have hosted our visits to China, bought equipment to set up a new C. elegans facility and learnt to work with C. elegans |
| Impact | New methods to address research questions about how microbes influence obesity. Bringing studies with human and mammalian models together with invertebrate model organisms (C. elegans) and bacterial models (E. coli). |
| Start Year | 2012 |
| Description | Pippa Stephens article |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Articles initiated a lot of discussion on the internet and further interest from the media After this event, there was more public interest in my Liping Zhao's research and hopefully, my research too. |
| Year(s) Of Engagement Activity | 2012 |
| URL | http://www.ft.com/cms/s/0/0b7af978-493a-11e2-9225-00144feab49a.html#axzz3Ix3Anqwl |
| Description | Shanghai Institute for Pediatric Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk sparked questions and discussion, After my talk, clinical researchers asked for more information. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Shanghai Jiao Tong Talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | Talk sparked questions and discussions After the talk, there was a new perspective from some of the audience |
| Year(s) Of Engagement Activity | 2012 |