China:UK collaborative exchange: Systemic signalling in plants

Lead Research Organisation: University of Warwick
Department Name: School of Life Sciences

Abstract

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Publications

10 25 50
 
Description CRISPR/Cas9 is a revolutionary gene editing technique. In plants it has been used successfully but only by making transgenic plants expressing the CRISPR RNAs and/or the Cas9 protein. We have shown that we can use virus vectors to express the CRISPR RNAs and the Cas9 protein in non-transgenic plants thus enabling this gene-editing technology to be used in a manner that doesn't involve the production and use of transgenic plants (therefore the resulting plants are likely to be subject to less restrictions and licensing before commercial release).
Exploitation Route We will be able to develop rapid and simple non-integrative CRISPR gene editing approaches that don't involve integration of foreign DNA into the plant's genome
Sectors Agriculture, Food and Drink

 
Description China Partnering Award: Transgene-free Gene Editing in Plants
Amount £30,204 (GBP)
Funding ID BB/T018259/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2020 
End 03/2024
 
Description Warwick-Hangzhou Joint lab 
Organisation Hangzhou Normal University, China
Country China 
Sector Academic/University 
PI Contribution Joint research projects Reciprocal exchange visits Joint publications. Training of early career scientists.
Collaborator Contribution Joint research projects. Reciprocal exchange visits. Joint publications. Joint PhD and MSc student supervision
Impact Establishment of a Warwick-Hangzhou Joint Laboratory. Collaborative projects (Multi-disciplinary: Virology & Plant Physiology/Biochemistry) 11 joint publications to date. Visiting Professorships awarded to Dr Jackson from Hangzhou University, and to Prof Hong from Warwick University. Joint PhD and MSc student supervision
Start Year 2013