13TSB_ENDANI: Automated pen-side faecal egg counting system for grazing livestock

Lead Research Organisation: University of Bristol
Department Name: Clinical Veterinary Science

Abstract

We propose to develop automated methods for counting parasite eggs in faecal samples from grazing livestock (sheep, goats, cattle, horses and pigs), and for distinguishing the eggs of different parasites. The proposed technology will form the basis of novel pen-side tests to indicate levels of infection in individuals and groups of animals at the point of care, and hence inform decisions on treatment. As a result, use of antiparasitic drugs will become more efficient and more sustainable, and select less strongly for drug resistance, which currently threatens livestock health, welfare and productivity.

Technical Summary

We propose to develop automated methods for counting parasite eggs in faecal samples from grazing livestock (sheep, goats, cattle, horses and pigs), and for distinguishing the eggs of different parasites. The proposed technology will form the basis of novel pen-side tests to indicate levels of infection in individuals and groups of animals at the point of care, and hence inform decisions on treatment. As a result, use of antiparasitic drugs will become more efficient and more sustainable, and select less strongly for drug resistance, which currently threatens livestock health, welfare and productivity.

Planned Impact

The entire proposal is aimed to have impact, by creating and applying novel methods of parasite egg detection in the faeces of grazing animals. This will greatly simplify and facilitate the use of faecal worm egg counts (FEC) in the management of helminth parasites in farming systems (including cattle, sheep, horses and pigs), with clear benefits to animal health, farming efficiency and the environment.

Who will benefit from this research?

Farmers, consumers of animal products, the UK economy, participants in the project and the broader scientific, animal health and farming communities.

How will they benefit?

Economic benefits:
The farmer: reduced anthelmintic treatment costs, reduced production losses to infection, and improved sustainability of anthelmintic efficacy.

The consumer: lower prices of animal products, greater food security and stability of commodity prices, lower risk of anthelmintic residues in food, more ethical food production from healthy animals with reduced environmental impact.

UK economy: increased farming efficiency and food security and decreased greenhouse gas emissions.

The consortium, a profitable potential product and increased technical and marketing capacity for future animal health products and services.

Social benefits:
Improved resilience of marginal grazing systems in the UK and internationally, and enhanced health and welfare of grazing livestock.

Environmental benefits:
Reduced and more appropriately targeted anthelmintic use, attentuating adverse effects on the environment, for example through toxic effects on free-living invertebrates and decreased prey abundance for bats and other insectivores. Improved viability of organic farming. Reduction in greenhouse gas emissions due to increased production efficiency.

Publications

10 25 50
 
Description The project delivered an automated faecal egg counting system, able to be modified for different sectors and combined with decision support systems developed in parallel. Details are not publicly available in order to protect IP of our SME partners pending commercialisation. Planning for exploitation is ongoing, led by Arrow Labs, who secured a further IUK grant in order to build a prototype system suitable for demonstration to commercial partners in order to raise investment for product development and marketing. This is ongoing.
Exploitation Route The system is flexible and could be applied to a number of agricultural and medical sectors. Arrow Labs Ltd., our commercial partners, have - since the end of the grant and through our academic contacts - been invited to contribute to the WormStars international consortium for combating helminth infections in people, with their field-based technology a potential diagnostic indicator of infection. As far as we are aware no specific funding or impact has arisen from that connection yet but might still materialise.
Sectors Agriculture, Food and Drink,Environment,Healthcare

URL http://www.arrow-labs.co.uk/
 
Description The research has informed technical development of the automated faecal egg counting and decision support system. Findings have not been published in order to protect intellectual property of our SME partner pending commercialisation. Our partner secured a IUK grant to develop the technology arising form the current project into a prototype to show to potential commercial partners, with a view to progressing to market. This is ongoing.
First Year Of Impact 2017
Sector Agriculture, Food and Drink
Impact Types Economic

 
Description Fully Automated Analysis of Parasitic Egg Cells in Faecal Preparations
Amount £24,750 (GBP)
Funding ID 131682 
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 07/2014 
End 11/2014
 
Title GLOWORM-EQ 
Description An adaptation of the GLOWORM-FL model to equine nematodes, for decision support outputs of this project. 
Type Of Material Computer model/algorithm 
Provided To Others? No  
Impact None to date, but will help to inform parasite control strategies for equine nematodes both as part of project outputs and by giving other researchers access to the model. 
 
Description LiHRA meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Basic details of the prototype system (as far as IP protection and NDA allow) were presented to an expert group at the Livestock Helminth Research Alliance (LiHRA) meeting in Crete, Greece, Sept 2016. The group included researchers from several European countries including specialist veterinary practitioners and persons engaged in human helminth control policy (WHO, Gates foundation). As a result of the meeting our SME partner was consulted on adapting their system to human healthcare, specifically monitoring and evluation of mass deworming programmes in developing countries. Moreover, they were invited to join a consortium applying for EU H2020 funding for commercialisation of pen-side diagnostic tests for animal disease.
Year(s) Of Engagement Activity 2016
URL http://www.lihra.eu/