Wound Triggered Synergistic Anti Biofilm Frameworks

Lead Research Organisation: University of Liverpool
Department Name: Institute of Ageing and Chronic Disease

Abstract

This is in the full application from the commercial partner lead

Technical Summary

This is in the application from the commercial partner lead

Planned Impact

This is in the application from the commercial partner lead

Publications

10 25 50
 
Description We have filed a patent on Anti-microbial Compositions PCT/GB2017/051243 published 9/11/17 that uses the antimicrobial properties of some metals to provide antimicrobial materials for wound dressings.
Exploitation Route These invention could be used in wound dressings and food packaging and would provide an alternative to antibiotics in many situations.
Sectors Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

 
Description The lead company have significantly raised their profile and reputation in their field by conducting this research project with the University of Liverpool. This project has clearly demonstrated the company are research active.
First Year Of Impact 2016
Sector Healthcare,Manufacturing, including Industrial Biotechology
Impact Types Economic

 
Title ANTI-MICROBIAL COMPOSITIONS 
Description A metal-EDTA compound/complex for combatting biofilms and/or treating wounds. The compound/complex comprises EDTA and from two to four metal ions. Of those two to four metal ions, at least two are different metal ions selected from Ag, Al, Au, Ba, Bi, Tl, Ce, Co, Cu,Fe, Ga, Ir, Mo,Rh, Ru, Ti, and Zn ions. The metal-EDTA compound/complex may exhibit any one or more of anti-microbial, anti-biofilm and anti-inflammatory activities in use and may increase the susceptibility of a biofilm and the microorganisms within said biofilmto attack by anti-microbial agents, helping to remove and sanitise the biofilm. A composition, wound dressing and medical device comprising the metal-EDTA complex are also provided. Uses of the metal-EDTA compound/complex as a medicament and/or to sanitise and/or substantially remove a biofilm from a substrate are also disclosed. 
IP Reference WO2017191453 
Protection Patent application published
Year Protection Granted 2017
Licensed Commercial In Confidence
Impact Awaiting exploitation in new wound dressings