Feasibility study of a novel class of self-associating amphiphilic anti-microbials.
Lead Research Organisation:
University of Kent
Department Name: Sch of Biosciences
Abstract
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Organisations
Publications
Allen N
(2020)
Towards the Prediction of Antimicrobial Efficacy for Hydrogen Bonded, Self-Associating Amphiphiles.
in ChemMedChem
Ellaby R
(2021)
Identification of organophosphorus simulants for the development of next-generation detection technologies
in Organic & Biomolecular Chemistry
Tyuleva SN
(2018)
A symbiotic supramolecular approach to the design of novel amphiphiles with antibacterial properties against MSRA.
in Chemical communications (Cambridge, England)
White LJ
(2020)
Controllable hydrogen bonded self-association for the formation of multifunctional antimicrobial materials.
in Journal of materials chemistry. B
| Description | We developed a series of novel supermolecular compounds with significant bactericidal antimicrobial activity. |
| Exploitation Route | Patent has been submitted and further funding is being sought to extend project. |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Title | CCDC 1866274: Experimental Crystal Structure Determination |
| Description | Related Article: Stilyana N. Tyuleva, Nyasha Allen, Lisa J. White, Antigoni Pépés, Helena J. Shepherd, Paul J. Saines, Rebecca J. Ellaby, Daniel P. Mulvihill, Jennifer R. Hiscock|2018|Chem.Commun.|55|95|doi:10.1039/C8CC08485H |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| URL | http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc20n0d3&sid=DataCite |
| Title | CCDC 1866275: Experimental Crystal Structure Determination |
| Description | Related Article: Stilyana N. Tyuleva, Nyasha Allen, Lisa J. White, Antigoni Pépés, Helena J. Shepherd, Paul J. Saines, Rebecca J. Ellaby, Daniel P. Mulvihill, Jennifer R. Hiscock|2018|Chem.Commun.|55|95|doi:10.1039/C8CC08485H |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| URL | http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc20n0f4&sid=DataCite |
| Title | "Antimicrobial compounds" |
| Description | Development of a novel series of Naturally evolved bacterial strains have now been identified that are resistant to treatment with all known classes of antimicrobial agent currently marketed. In 2015 we discovered, developed and patented (18/07/2017) a novel class of Supramolecular Self-associating Antimicrobials (SSAs) which have the potential to initiate a step-change in antibiotic development. |
| IP Reference | GB1711555.1 |
| Protection | Patent application published |
| Year Protection Granted | |
| Licensed | No |
| Impact | None yet |