University of York UKRI Innovation Fellowships: BBSRC Flexible Talent Mobility Accounts
Lead Research Organisation:
University of York
Department Name: Registrar
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
- University of York (Lead Research Organisation)
- Frontier Agriculture Ltd (Collaboration)
- Italian National Research Council (Collaboration)
- Unilever (Netherlands) (Collaboration)
- Croda International (Collaboration)
- Princeton University (Collaboration)
- Kutnowska Hodowla Buraka Cukrowego Sp. z o. o. (Collaboration)
- Novartis Institutes for BioMedical Research (NIBR) (Collaboration)
- Elsoms Seeds (Collaboration)
People |
ORCID iD |
| Rachel Curwen (Principal Investigator) |
Publications
Emrich-Mills TZ
(2021)
A recombineering pipeline to clone large and complex genes in Chlamydomonas.
in The Plant cell
Knight SJ
(2020)
Small scale fungal community differentiation in a vineyard system.
in Food microbiology
Meyer MT
(2020)
Assembly of the algal CO2-fixing organelle, the pyrenoid, is guided by a Rubisco-binding motif.
in Science advances
Saldivia M
(2020)
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.
in Nature microbiology
| Description | The aims of our FTMA were: Aim 1 - Attracting and retaining the best early career staff Aim 2 - Enhancing the impact of our research through partnership The award has enabled 11 talented early career researchers to experience a secondment, either from an international academic organisation visiting York, or for UoY researchers to spent time in Industry or an international academic laboratory. Of wider benefit is the enhanced collaboration with external organisations for the teams involved. Four of the secondees met with Rutherford Fund criteria. |
| Exploitation Route | A wide range of sectors are covered by this award and the benefits are continuing to accrue and to be taken forward by the industrial partners. |
| Sectors | Agriculture, Food and Drink,Chemicals,Environment,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Description | The awards supported 11 secondees. Three examples of outcomes are as follows: Funding awarded to Professor Ian Bancroft (Department of Biology) supported a secondment to foster the development and readiness for adoption of new varieties of rapeseed. These varieties provide an increased amount of valuable compounds in comparison to the traditional varieties with the aim of reducing the amount of growing land needed. The award allowed industrial partners to evaluate processes for the production of these valuable compounds and aided further talks towards funding commercialisation of the new varieties. The secondee gained a deeper understanding of the supply chain and legislative frameworks governing plant breeding for new crops through direct engagement with regulatory bodies. A start-up company, Nuspec Bioscience Ltd, was established in July 2019 by the grant holder and the secondee. The business aims to commercialise the knowhow of the grant holder's research group and has completed its first commission (for an EU-based breeder). Funding awarded to Professor Paul Walton (Department of Chemistry) supported the work of PDRA Dr Luisa Ciano who developed a collaboration with the Institute of Bioscience and Bioresources in Naples Italy and in tandem her own independent research project. Dr Ciano has subsequently been awarded the Anne McClaren Fellowship at the University of Nottingham. Funding awarded to Professor Gavin Thomas (Department of Biology) supported the secondee Dr Rudden to collaborate with Unilever on body odour production. Unilever have now paid for full genome sequencing of the responsible bacteria by PacBio sequencing and the results from this have underpinned an application to the October 2020 BBSRC Responsive mode with the Dr Rudden as the named PDRA. |
| Sector | Agriculture, Food and Drink,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Economic |
| Description | Fellowship for JL |
| Amount | $180,724 (USD) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2020 |
| End | 11/2023 |
| Title | TurboID |
| Description | The Mackinder lab has now developed a proximity labelling tool called TurboID that is a variant of the APEX2 method the FMTA funding was for. |
| Type Of Material | Model of mechanisms or symptoms - non-mammalian in vivo |
| Year Produced | 2021 |
| Provided To Others? | No |
| Impact | It is providing novel insight into algal CO2 fixation, with the knowledge guiding ongoing plant engineering work to improve photosynthesis Although early stage we are establishing collaboration based on the developed method A manuscript is in preparation |
| Description | Collaboration with Institute of Biosciences and Biosresources, Naples, Italy |
| Organisation | Italian National Research Council |
| Department | Institute of Biosciences and Bioresources |
| Country | Italy |
| Sector | Public |
| PI Contribution | Collaboration through project postdoc |
| Collaborator Contribution | Ongoing advice and best practice sharing |
| Impact | None specific to date |
| Start Year | 2019 |
| Description | Collaboration with Novartis Institute of Tropical Diseases, USA |
| Organisation | Novartis Institutes for BioMedical Research (NIBR) |
| Department | Novartis Vaccines Institute for Global Health (NVGH) |
| Country | United States |
| Sector | Private |
| PI Contribution | Collaborative project involving drug discovery for neglected tropical diseases with York providing most of the molecular parasitology and Novartis providing all the chemistry. |
| Collaborator Contribution | Collaborative project involving drug discovery for neglected tropical diseases with York providing most of the molecular parasitology and Novartis providing all the chemistry. |
| Impact | In development |
| Start Year | 2016 |
| Description | Collaboration with Unilever on body odour production |
| Organisation | Unilever |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | full genome sequencing capability |
| Collaborator Contribution | research expertise |
| Impact | to come |
| Start Year | 2018 |
| Description | Croda |
| Organisation | Croda International |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research expertise |
| Collaborator Contribution | Interested in driving forward the commercialisation of novel industrial crops developed by Professor Bancroft group. Have provided access to specialised services including fatty acid analysis using gas chromatography. |
| Impact | Too early still |
| Start Year | 2019 |
| Description | Elsoms Seeds |
| Organisation | Elsoms Seeds |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research expertise |
| Collaborator Contribution | Interested in driving forward the commercialisation of novel industrial crops developed by Professor Bancroft group |
| Impact | Too early still |
| Start Year | 2019 |
| Description | Frontier Agriculture |
| Organisation | Frontier Agriculture Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research expertise |
| Collaborator Contribution | Interested in driving forward the commercialisation of novel industrial crops developed by Professor Bancroft group |
| Impact | Too early still |
| Start Year | 2019 |
| Description | New collaboration between University of York and plant breeding centre in Poland |
| Organisation | Kutnowska Hodowla Buraka Cukrowego Sp. z o. o. |
| Country | Poland |
| Sector | Private |
| PI Contribution | Establishment of new collaboration |
| Collaborator Contribution | Establishment of new collaboration |
| Impact | Nothing yet |
| Start Year | 2019 |
| Description | Strengthening collaboration with Jonikas lab |
| Organisation | Princeton University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Method development for cloning large complex genes has resulted in joint publications. |
| Collaborator Contribution | Academic input and funding strategy |
| Impact | Meyer MT, Itakura AK, Patena W, Wang L, He S, Emrich-Mills T, Lau CS, Yates G, Mackinder LCM, Jonikas MC (2020). Assembly of the Algal CO2-Fixing Organelle, the Pyrenoid, Is Guided by a Rubisco-Binding Motif. Science Advances 6:eabd2408. |
| Start Year | 2016 |
| Company Name | NUSPEC BIOSCIENCE LIMITED |
| Description | The business aims to commercialise the knowhow of Professor Bancroft's research group |
| Year Established | 2019 |
| Impact | It has completed its first commission (for an EU-based breeder) |
| Company Name | NUSPEC OIL LIMITED |
| Description | pioneering development of biodegradable and thermo-stable base oils for the lubricant and chemical industries. |
| Year Established | 2019 |
| Impact | completed pilot-scale production of a bright stock base oil that is bio-based and biodegradable called BS32. The product is currently only available for testing purposes. https://www.fuelsandlubes.com/nuspec-oil-offers-bio-based-bright-stock-base-oil-for-testing/ |
| Website | https://nuspec-oil.com/ |
| Description | Knowledge exchange seminar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | The award led to a knowledge-exchange seminar in 2019 to discuss the effect of heterosis within different plants species. The seminar played a crucial role in building collaboration between the University of York and the plant breeding sector in Poland. This event promoted the research carried out at the University of York. This valuable knowledge-exchange event contributed also to the understanding of the heterosis and future research requirements in crop species like sugar beet, wheat and oilseed rape. The award allowed secondee to participate in individually designed training programme led by industrial collaborators. Secondee gained deeper understanding of industrial crops supply chain and legislative frameworks in plant breeding through direct engagement with regulatory bodies. As part of the secondment, polish breeders attended organised trips to the Biorenewable Development Centre and Breckenholmes. |
| Year(s) Of Engagement Activity | 2019 |