US Partnering Award: An integrative approach to understanding the GnRH pulse generator: combining in-vitro, in-vivo and in-silico methodologies.
Lead Research Organisation:
King's College London
Department Name: Women's Health
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Lass G
(2022)
GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice.
in Journal of neuroendocrinology
Plain Z
(2022)
Modelling KNDy neurons and gonadotropin-releasing hormone pulse generation.
in Current opinion in endocrine and metabolic research
| Description | We have been able to incorporate some of the in-vitro data from our American colleagues into the mathematical model to enhance it's efficiency and calibration |
| Exploitation Route | Not relevant as the award is progressing very very well |
| Sectors | Education,Healthcare,Pharmaceuticals and Medical Biotechnology |