Microbial production of human milk fat substitute

Lead Research Organisation: Rothamsted Research
Department Name: Plant Sciences and the Bioeconomy

Abstract

Vegetable fats and oils (triacylglycerols) are an important source of human nutrition. They can account for a substantial proportion of the calories in the human diet. The nutritional properties of these fats and oils depend on the types of fatty acids that are attached at each of the three positions on their glycerol backbone. It has long been a goal of biotechnologists to adapt organisms to make 'designer' oils that are tailored for specific applications. The aim of this work is to develop a new production platform that produces a speciality oil for human nutrition.

Publications

10 25 50
 
Description The project has produced strains of yeast that produce fat that more closely mimics the chemical structure of human milk fat and could therefore be used as an ingredient in infant formula.
Exploitation Route The outcomes could be used by food manufacturers to make infant formula that more closely match human milk, and potentially also to make more sustainable substitutes for meat and dairy.
Sectors Agriculture, Food and Drink

 
Description Collaborative agreement signed with an industry partner
First Year Of Impact 2022
Sector Agriculture, Food and Drink
Impact Types Economic

 
Description Collaborative agreement signed with a food ingredient company 
Organisation AAK AB
Country Sweden 
Sector Private 
PI Contribution Collaboration founded on this project and background IP generated by my research team.
Collaborator Contribution In kind contribution and potential route to IP licencing and commercialisation of product.
Impact Confidential
Start Year 2021