Spatio-temporal And Structural Characterization Of Host Recognition By Novel Virus-like Entities
Lead Research Organisation:
University of York
Department Name: Biology
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Bardy P
(2024)
A stargate mechanism of Microviridae genome delivery unveiled by cryogenic electron tomography.
in bioRxiv : the preprint server for biology
| Description | This project was a small travel award that allowed a PhD student from a Canadian collaborator's lab to visit York for 3 months to carry out super-resolution microscopy experiments. Achievements: 1)The experiments were successful in producing high resolution, publication quality of fluorescently tagged proteins bound to cells and we hope to publish these in due course as part of a larger study. 2) Collaboration between York and UBC was cemented, knowledge exchange occurred and this led to a publication including authors from both labs. 3) The PhD student gained valuable experience and training on advanced light microscopy and cryo-EM provided by the applicants and the York Technology Facility staff, experience studying in the UK system, and experience working within a larger collegial lab group than at the home institute. |
| Exploitation Route | The PhD student will use her experiences to guide future research. The research outcomes will form part of a future publication on host-virus interactions, which could have impact on the field of synthetic biology, microbial evolution and horizontal gene transfer. |
| Sectors | Education Environment Healthcare |