China:UK collaborative exchange: Systemic signalling in plants
Lead Research Organisation:
University of Warwick
Department Name: School of Life Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
Stephen Jackson (Principal Investigator) |
Publications
Zhang X
(2020)
An RNAi suppressor activates in planta virus-mediated gene editing.
in Functional & integrative genomics
SARI L
(2016)
Development of a Transient Viral CRISPR Expression System to Manipulate Flowering Time in Plants Development of a Transient Viral CRISPR Expression System to Manipulate Flowering Time in Plants
in International Journal of Applied and Physical Sciences
Spanudakis E
(2014)
The role of microRNAs in the control of flowering time.
in Journal of experimental botany
Yu Z
(2018)
Multigene editing via CRISPR/Cas9 guided by a single-sgRNA seed in Arabidopsis.
in Journal of integrative plant biology
Taylor JL
(2017)
FLC expression is down-regulated by cold treatment in Diplotaxis tenuifolia (wild rocket), but flowering time is unaffected.
in Journal of plant physiology
Hong Y
(2015)
Floral induction and flower formation--the role and potential applications of miRNAs.
in Plant biotechnology journal
Qin C
(2017)
Roles of Dicer-Like Proteins 2 and 4 in Intra- and Intercellular Antiviral Silencing.
in Plant physiology
Qin C
(2017)
A Virus-Induced Assay for Functional Dissection and Analysis of Monocot and Dicot Flowering Time Genes.
in Plant physiology
Chen W
(2018)
A Genetic Network for Systemic RNA Silencing in Plants
in Plant Physiology
Chen W
(2015)
Tuning LeSPL-CNR expression by SlymiR157 affects tomato fruit ripening.
in Scientific reports
Chen W
(2015)
Requirement of CHROMOMETHYLASE3 for somatic inheritance of the spontaneous tomato epimutation Colourless non-ripening.
in Scientific reports
Taylor Jemma Louise
(2015)
Delayed bolting in rocket for improved quality and greater sustainability
Description | CRISPR/Cas9 is a revolutionary gene editing technique. In plants it has been used successfully but only by making transgenic plants expressing the CRISPR RNAs and/or the Cas9 protein. We have shown that we can use virus vectors to express the CRISPR RNAs and the Cas9 protein in non-transgenic plants thus enabling this gene-editing technology to be used in a manner that doesn't involve the production and use of transgenic plants (therefore the resulting plants are likely to be subject to less restrictions and licensing before commercial release). |
Exploitation Route | We will be able to develop rapid and simple non-integrative CRISPR gene editing approaches that don't involve integration of foreign DNA into the plant's genome |
Sectors | Agriculture, Food and Drink |
Description | China Partnering Award: Transgene-free Gene Editing in Plants |
Amount | £30,204 (GBP) |
Funding ID | BB/T018259/1 |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2021 |
End | 03/2025 |
Description | Warwick-Hangzhou Joint lab |
Organisation | Hangzhou Normal University, China |
Country | China |
Sector | Academic/University |
PI Contribution | Joint research projects Reciprocal exchange visits Joint publications. Training of early career scientists. |
Collaborator Contribution | Joint research projects. Reciprocal exchange visits. Joint publications. Joint PhD and MSc student supervision |
Impact | Establishment of a Warwick-Hangzhou Joint Laboratory. Collaborative projects (Multi-disciplinary: Virology & Plant Physiology/Biochemistry) 11 joint publications to date. Visiting Professorships awarded to Dr Jackson from Hangzhou University, and to Prof Hong from Warwick University. Joint PhD and MSc student supervision |
Start Year | 2013 |