A Freedom to Operate Proposal to Research Targeted Drug Delivery to the Cornea of the Eye Via Thin-Film Slow Release Technology.
Lead Research Organisation:
Cardiff University
Department Name: Optometry and Vision Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Andrew Quantock (Principal Investigator) |
Publications
Akhbanbetova A
(2017)
A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal.
in Journal of ophthalmology
Baba K
(2020)
Cell jamming, stratification and p63 expression in cultivated human corneal epithelial cell sheets.
in Scientific reports
Bains KK
(2019)
Recovering vision in corneal epithelial stem cell deficient eyes.
in Contact lens & anterior eye : the journal of the British Contact Lens Association
Chan W
(2016)
Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film.
in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Morgan SR
(2020)
Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis.
in International journal of pharmaceutics
| Description | That we have freedom to operate in our quest to discover new ocular drug delivery modalities |
| Exploitation Route | Research in a similar field |
| Sectors | Healthcare,Pharmaceuticals and Medical Biotechnology |
| Description | Follow on Fund |
| Amount | £144,900 (GBP) |
| Funding ID | BB/N022106/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2017 |
| End | 04/2018 |
| Description | Targeted Drug Delivery to the Cornea of the Eye Via Medicated Contact Lenses and Mucoadhesive Thin Films |
| Amount | £511,563 (GBP) |
| Funding ID | BB/S004874/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2019 |
| End | 01/2021 |
| Description | Targeted Drug Delivery to the Cornea of the Eye Via Thin-Film Slow Release Technology. |
| Amount | £111,052 (GBP) |
| Funding ID | BB/N022106/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 08/2018 |
| Description | Thea collaboration |
| Organisation | Thea Pharmaceuticals Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Developing new drug delivery technology with commercial medical partner of contact lens drug delivery research |
| Collaborator Contribution | Expertise in contact lens manufacture and sales |
| Impact | NDA signed for new grant application |
| Start Year | 2017 |
| Title | CRYOPROBE |
| Description | The invention relates to a medical device, including interchangeable parts thereof, for performing corneal cell freezing wherein said device comprises an elongate member having a flow line system through which a cryogenic fluid flows to cool a cryoprobe tip which tip is fixed and comprises a concave epithelial surface contact member. |
| IP Reference | WO2013034907 |
| Protection | Patent granted |
| Year Protection Granted | 2013 |
| Licensed | No |
| Impact | Pending |