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Tracing the origins of foot and mouth disease outbreaks

Lead Research Organisation: THE PIRBRIGHT INSTITUTE
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The objectives of this project are (1) to show the genetic relationships between new isolates of FMD virus causing outbreaks of disease around the world with those already held in the WRL for FMD; (2) to identify and monitor the appearance of new strains of FMD virus in the field by comparison with historical isolates; and (3) to determine if intertypic and/or intratypic recombination can be detected in FMD viruses isolated from outbreaks of disease in the field.

Planned Impact

unavailable

Publications

10 25 50
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Abdul-Hamid NF (2011) Phylogeography of foot-and-mouth disease virus types O and A in Malaysia and surrounding countries. in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

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Alkhamis MA (2009) Temporospatial clustering of foot-and-mouth disease outbreaks in Israel and Palestine, 2006-2007. in Transboundary and emerging diseases

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Ayelet G (2009) Genetic characterization of foot-and-mouth disease viruses, Ethiopia, 1981-2007. in Emerging infectious diseases

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Habiela M (2010) Molecular characterization of foot-and-mouth disease viruses collected from Sudan. in Transboundary and emerging diseases

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Khounsy S (2009) Molecular epidemiology of foot-and-mouth disease viruses from South East Asia 1998-2006: the Lao perspective. in Veterinary microbiology

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Knowles NJ (2009) Recent spread of a new strain (A-Iran-05) of foot-and-mouth disease virus type A in the Middle East. in Transboundary and emerging diseases

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Rweyemamu M (2008) Epidemiological patterns of foot-and-mouth disease worldwide. in Transboundary and emerging diseases

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Valarcher JF (2009) Multiple origins of foot-and-mouth disease virus serotype Asia 1 outbreaks, 2003-2007. in Emerging infectious diseases

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Waheed U (2011) Molecular characterisation of foot-and-mouth disease viruses from Pakistan, 2005-2008. in Transboundary and emerging diseases

 
Description The epidemiology of foot-and-mouth disease (FMD) was studied worldwide and genetic sequence data used to trace the origins of disease outbreaks and map the movement of FMD viruses around the world.
Exploitation Route The sequences determined in the study have been added to the FMD World Reference Laboratory sequence database and have been and will be used in the study of FMD epidemiology. The sequences which have been published in international journals have also been submitted to the public sequence databases. Many other researchers have taken advanage of the sequence data in their studies.
Sectors Agriculture

Food and Drink
URL http://www.wrlfmd.org/fmd_genotyping/
 
Description The genetic tracing of foot-and-mouth disease (FMD) outbreaks has had an impact on disease control in many countries (e.g. Egypt, where an increased incidence of virus movements from sub-Saharan Africa were demonstrated).
First Year Of Impact 2008
Sector Agriculture, Food and Drink
Impact Types Economic

Policy & public services