Molecular assembly using gold catalysis
Lead Research Organisation:
University of St Andrews
Department Name: Chemistry
Abstract
The development of catalytic methods leading to little or no waste is an area of crucial importance in terms of energy and materials economy. The present proposal presents strategies to assemble complex molecular architectures or value-added compounds using simply synthesized organogold complexes. The proposal adopts a two-prong approach. On the one side the design and synthesis of organogold catalysts are proposed and on the other some of the catalysts already synthesized by our group and the novel ones are proposed to enable important chemical transformations. These range from hydration reactions to tandem reactions leading to multiple bond formations in a single step. The aim of the proposal is to develop useful synthetic tools, readily usable by synthetic chemists permitting facile protocols enabling the synthesis of complex molecular assemblies.
Organisations
People |
ORCID iD |
| Steven Nolan (Principal Investigator) |
Publications
Boogaerts II
(2010)
Carboxylation of C-H bonds using N-heterocyclic carbene gold(I) complexes.
in Journal of the American Chemical Society
Boogaerts II
(2011)
Direct C-H carboxylation with complexes of the coinage metals.
in Chemical communications (Cambridge, England)
Boogaerts II
(2010)
Carboxylation of N-H/C-H bonds using N-heterocyclic carbene copper(I) complexes.
in Angewandte Chemie (International ed. in English)
Brulé E
(2011)
Polymerization of Racemic ß-Butyrolactone Using Gold Catalysts: A Simple Access to Biodegradable Polymers
in Organometallics
Cera G
(2012)
One-pot gold-catalyzed synthesis of azepino[1,2-a]indoles.
in Angewandte Chemie (International ed. in English)
Diebolt O
(2010)
Mixed Phosphite/ N -Heterocyclic Carbene Complexes: Synthesis, Characterization and Catalytic Studies
in Organometallics
Dupuy S
(2012)
The fluoride-free transmetalation of organosilanes to gold.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Dupuy S
(2011)
Decarboxylation of aromatic carboxylic acids by gold(I)-N-heterocyclic carbene (NHC) complexes.
in Chemical communications (Cambridge, England)
Fortman G
(2010)
Solution Calorimetric Study of Ligand Exchange Reactions in the [Au(L)Cl] System (L = Phosphine and Phosphite)
in Organometallics
Fortman G
(2010)
A Versatile Cuprous Synthon: [Cu(IPr)(OH)] (IPr = 1,3 bis(diisopropylphenyl)imidazol-2-ylidene)
in Organometallics