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Droplet-based Microfluidic Platform for Intracellular Ion Channel Drug Discovery

Lead Research Organisation: University of Glasgow
Department Name: College of Medical, Veterinary, Life Sci

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Zagnoni M (2018) Droplet-based Microfluidic Platform for Intracellular Ion Channel Drug Discovery - EPSRC in Impact

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Zhang Y (2020) Functionalisation of human chloride intracellular ion channels in microfluidic droplet-interface-bilayers. in Biosensors & bioelectronics

 
Description We have developed and tested a new technology for the screening of membrane proteins in microfluidics.
Exploitation Route This technology has been designed to look at human ion channels involved in disease states. There is potential for this technology to be used for drug discovery with other human membrane proteins, or membrane proteins from any other organism.
Sectors Pharmaceuticals and Medical Biotechnology
URL https://www.ingentaconnect.com/content/sil/impact/2018/00002018/00000007/art00024