Plasma-activated antimicrobial hydrogel therapy (PAHT) for combatting infections in diabetic foot ulcers
Lead Research Organisation:
University of Glasgow
Department Name: College of Medical, Veterinary, Life Sci
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
Publications
Brown JL
(2022)
Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model.
in NPJ biofilms and microbiomes
Gaur N
(2023)
Cold Atmospheric Plasma-Activated Composite Hydrogel for an Enhanced and On-Demand Delivery of Antimicrobials.
in ACS applied materials & interfaces
Gülmez D
(2022)
Investigating Dual-Species Candida auris and Staphylococcal Biofilm Antiseptic Challenge.
in Antibiotics (Basel, Switzerland)
Short B
(2023)
There Is More to Wounds than Bacteria: Fungal Biofilms in Chronic Wounds
in Current Clinical Microbiology Reports
| Description | Plamsa jets have the capacity to release antimicrobials from a dressing and effectively kill bacteria and fungi. |
| Exploitation Route | - Develop chemistry that is applicable to plasma release - Understanding of parameters for plasma release of compounds |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Title | Polymicrobial biofilm development |
| Description | This tool is a complex wound biofilm that can be used to assess inflammation and the effects of antimicrobials. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Facilitated the methods to secure EPSRC grant |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991182/ |
| Description | School visit to Gartocharn Primary School |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | 90 school children learned about the importance of biofilms. We made biofilms bacteria on Petri dishes with PlayDoh and investigated bacteria from the mouth with a micrscope. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://twitter.com/ramage_gordon?lang=en-GB |
