Image-driven subject-specific spine models
Lead Research Organisation:
CARDIFF UNIVERSITY
Department Name: Sch of Engineering
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Williams D
(2023)
BORS/BJR TRAVELLING FELLOWSHIP: IMAGE-DRIVEN SUBJECT-SPECIFIC SPINE MODELS: DEVELOPING A NOVEL TOOL TO MEASURE IN VIVO LOADING
in Orthopaedic Proceedings
Williams J
(2024)
PUBLIC AND PATIENT ENGAGEMENT IN RESEARCH TO DEVELOP TECHNOLOGIES FOR PREDICTING SPINE LOADS IN VIVO
in Orthopaedic Proceedings
| Description | The project has resulted in a range of new tools designed to inform the measurement of spine movement and posture and will enable new tools to measure the response of patients to surgical and physiotherapy interventions. The methods that have been developed range from MRI and X-ray imaging and modelling movement of the back. These technologies have advanced understanding across a multidisciplinary , cross-UK team and have led to further funded studies, pilot data, and new clinician-led research questions |
| Exploitation Route | The findings are being used across the UK to generate new engineering and biological tools that address the occurrence of OA and its impact, a range of new diagnostics, management and treatment options, and new ways to support and understand patient response to interventions. |
| Sectors | Healthcare |
| Description | Contributed to the Welsh Government consultation on Arthritis and Long-term Musculoskeletal Conditions in adults |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| URL | https://gov.wales/arthritis-and-long-term-musculoskeletal-conditions-adults |
| Description | Presentation of Clinical acceptance of technology in remote rehabilitation assessment: Addressing urgent COVID challenges to drive future technology transfer - to the Welsh Government COVID Tag |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | RAEng Consultation - challenge of the ageing population and multimorbidities |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | RAEng Healthcare Technology Policy Group- contribution to the Prime Ministers Council for Science and Technology (CST) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | RAEng Healthcare Technology Policy Group- contribution to the Prime Ministers Council for Science and Technology (CST) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | RSC Commission on future of surgery - C Holt contributed to the Call for Evidence for the "Implications for Future Surgical Technology" document via the Royal Academy of Engineering Biomedical Engineering Panel |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| URL | https://futureofsurgery.rcseng.ac.uk/?_ga=2.104617412.577568556.1550158526-60008457.1547478615 |
| Description | Royal Academy of Engineering submitted response to government's 10-Year Health Plan consultation at the end of November 2024 - available on the Academy's website soon. |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | invited contribution to the Welsh Government - Health Technology Wales Round Table on Medical Technology Research, Development and Translation in Wales with the published a report: Medical Technology Innovation for Wales |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| URL | https://www.learnedsociety.wales/medtech-innovation-for-wales/ |
| Description | PI - Dr David Williams - MRI-based spine models for patient specific surgical planning: A clinically driven approach to developing new validated surgical tools |
| Amount | £536,844 (GBP) |
| Funding ID | MC_PC_19033 |
| Organisation | Cardiff University |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 03/2023 |
| Description | Clinical drivers for spine imaging and modelling - Consultant Radiology for optimising imaging modalities for model creating, image registration and virtual surgical planning - |
| Organisation | Cardiff and Vale University Health Board |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | The in vivo dual plane X-ray imaging protocols designed for collection of healthy volunteer data have involved the Cardiff team and consultation with the Exeter team to optimise the protocols for the activities involving spine loading. IRAS and NHS Approval processes have been adhered to, supported by Cardiff University Research Governance, and the letter of approval is pending following minor changes to the Patient Information Sheet |
| Collaborator Contribution | Designing the protocols for imaging and motion analyses for the in vivo aspect of this study at Cardiff has involved consultations with Consultant Spine Surgeon (member of the Project Advisory Board), and Consultant Radiologist (as Clinical sign off for the protocols involving ionising radiation. |
| Impact | Healthy Participant Study documents including: - Protocol - Patient Information Sheet - Consent form |
| Start Year | 2022 |
| Description | Patient and Public Involvement Input to the Project Advisory Board and IRAS Ethics Approval Application - Dr Steven Blackburn |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The Cardiff Team have worked on the IRAS Ethics Application to produce an optimised Protocol, Participant Information Sheet, Consent Form and all associated documents. |
| Collaborator Contribution | Partner member of the Project Advisory Group - Dr Steven Blackburn - Institute of Applied Health Research - Associate Professor - has advised at PAG meetings and also contributed to review of the IRAS documentation. this participation has ensured that the PIS/Consent Form etc are targeted to an appropriate audience for the healthy participant recruitment. Steven is the lead for public involvement in NIHR Research Design Service (RDS) West Midlands. Current Chair of the national RDS Public Involvement Community and Public Involvement Lead for the RDS National Office, responsible for the delivery of a national RDS Public Involvement Strategy. He has contributed to several NIHR initiatives to improve the quality of public involvement and engagement in research. |
| Impact | In vivo spine imaging IRAS documentation that has factored in patient/public involvement: - Participant Information Sheet - Consent Form - Protocol has allowed submission and approval of the in vivo imaging aspects of the study. |
| Start Year | 2021 |
| Description | Patient and Public Involvement Input to the Project Advisory Board and IRAS Ethics Approval Application - Dr Steven Blackburn |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The Cardiff Team have worked on the IRAS Ethics Application to produce an optimised Protocol, Participant Information Sheet, Consent Form and all associated documents. |
| Collaborator Contribution | Partner member of the Project Advisory Group - Dr Steven Blackburn - Institute of Applied Health Research - Associate Professor - has advised at PAG meetings and also contributed to review of the IRAS documentation. this participation has ensured that the PIS/Consent Form etc are targeted to an appropriate audience for the healthy participant recruitment. Steven is the lead for public involvement in NIHR Research Design Service (RDS) West Midlands. Current Chair of the national RDS Public Involvement Community and Public Involvement Lead for the RDS National Office, responsible for the delivery of a national RDS Public Involvement Strategy. He has contributed to several NIHR initiatives to improve the quality of public involvement and engagement in research. |
| Impact | In vivo spine imaging IRAS documentation that has factored in patient/public involvement: - Participant Information Sheet - Consent Form - Protocol has allowed submission and approval of the in vivo imaging aspects of the study. |
| Start Year | 2021 |
| Description | IDSSSM website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A website has been created with the purpose of disseminating our project to a wider audience. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://idsssm.exeter.ac.uk/ |
| Description | PPIE Workshop - |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | The project involved the public in two ways: - initially to develop the paperwork used to recruit and consent participants in our study and secondly, to elicit opinions on our project and its future application. - invited members of the public to an engagement event held on 16th October 2023 to coincide with World Spine Day - a 90-minute in-person event included 12 adults across a wide range of ages who discussed our project communication, future directions of the research, concerns about the research protocol, concerns about data, and interest in the project team and research process. This engagement event was held in partnership with the Exeter Science Centre, a local educational charity committed to connecting the public with current research and industry. Our PPIE has informed how we perform our research and communicate it to a non-academic audience (e.g. the need to relate the research to everyday life, present risks in various ways, and be transparent about funding and future data sharing). It has also informed the creation of participant documentation and participant engagement activities in subsequent EPSRC-funded projects. The experience has also prompted us to rethink our perspective on the future of our current work. We had anticipated the public would be interested in how we could solve issues like back pain. While this topic was of interest, they indicated that we should approach this from the perspective of prevention by looking at healthy spines and the factors that affect them so that advice can be given on how to avoid the development of spinal disorders and pain. |
| Year(s) Of Engagement Activity | 2023 |