Ultrafast Optoelectronic Nanoscopy of Biological and Optoelectronic Systems

Lead Research Organisation: Imperial College London
Department Name: Chemistry

Abstract

One of the greatest challenges in modern nanotechnology is the ability to characterise individual molecules and molecular assemblies with high spatial and temporal resolution. A technology possessing these capabilities will have a broad range of applications in next-generation molecular electronics, and will help to solve major existing healthcare challenges, from early-stage biomarker detection to protein sequencing.
In the last decade, a variety of new methods emerged that tried to combine ultrafast optical tools with electronic sensors. The developed expertise brings us a unique opportunity to start a completely new type of experimental research - addressing individulal molecules and resolving their dynamics on all relevant timescales, from ps to ms and beyond.
In the proposed project, we aim to bring together cutting-edge developments in the fields of ultrafast spectroscopy and single-molecule tunnelling detection. We will develop a new experimental platform for the characterisation of molecular-scale objects, utilising nanodimensional electrical probes in concert with ultrafast optical methods. This combination will result in a robust and versatile new technique, Ultrafast Optoelectronic Nanoscopy (UON). UON's potential to overcome the limitations of scanning probe methods and to access the real-time evolution of molecular systems will be demonstrated by applying it to biological macromolecules and plastic semiconductor devices.

Publications

10 25 50
 
Description Our team transformed a small electronic device, that resembles a tiny crack between two metal plates, into a tool that can detect light. We discovered that particles of light, called photons, can transfer electrons from one metal plate to another, allowing us to measure the properties of light. The most exciting property of this system is that our device can detect short pulses of light of any colour from ultraviolet to mid-infrared, making it useful in areas like photo detection and understanding the characteristics of light.
Exploitation Route Our research has uncovered a phenomenon that has wide-ranging applications in photonics, for example for compact and ultra-broadband detectors to detect ultrafast light pulses.
Furthermore, our findings can lead to the development of new types of chemical sensors that can detect individual molecules in the tiny space between two electrodes. These single-molecule sensors can be utilized in biology to identify and detect biomolecules without the need for labelling or modification.
Sectors Chemicals,Electronics,Energy,Healthcare

 
Description School Visit (St. Paul's school, London) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact I have presented a talk about about spectroscopy and its application in nanotechnology (including this nanoscopy project) at the school Science society meeting. About 20 students had attended, listened to the lecture, passed the quiz, and asked questions.
Year(s) Of Engagement Activity 2022