iRFSim for BSNs -Imaging based subject-specific RF simulation environment for wearable and implantable wireless Body Sensor Networks (BSNs)

Lead Research Organisation: Queen Mary University of London
Department Name: Sch of Electronic Eng & Computer Science

Abstract

With increasing sophistication of wearable and implantable medical devices and their integration with wireless sensors, ever-expanding ranges of therapeutic and diagnostic applications are being pursued by the research and commercial organisations. These new miniaturised wireless devices include, for example, context aware implanted pacemakers and cardiac defibrillators, wirelessly controlled valves in the urinary tract operating on-demand by the patients for restoring bladder control, and integrated drug-delivering therapeutic systems such as those used for fast-acting insulin in diabetics. For these devices, the wireless data-path used to interrogate and communicate with the implants represents one of the most significant research challenges in overall system design due to its significant power consumption and complex characteristics within the human body. While wireless communication through the air has been extensively studied, communication from implanted devices through the human body is a new area of study. The human body is an uninviting and often hostile environment for a wireless signal. Typical geometries of implantable devices, such as implantable cardiac defibrillators and pacemakers, implantable glucose sensors, endoscopic and drug-delivering capsule devices, vary from mm to cm ranges. Wireless implants are restricted to a compact antenna that needs to be fully characterised and effectively coupled to the transceiver. There is also an issue of low power consumption required by implantable devices and these two factors are highly related. In order to design power efficient in-body communication schemes, understanding the mechanism of wave propagation and attenuation inside human body is important, but so far has not been explored systematically. Accurate modelling of induced electromagnetic fields and propagation in the body is a prerequisite to the design of wearable and implantable wireless sensors. The difficulty of simulating electromagnetic field and radio propagation within the human body is mainly due to the morphological complexity of organs and their heterogeneous tissue characteristics, coupled with dynamic deformation and inter-subject variations. In terms of how radiowave attenuates inside the body and the associated field behaviour around the body surface, there is so far limited knowledge. In this case, the characteristics of in vivo multiple path reflection is different and in vivo radio propagation is expected to be subject-specific and influenced by organ deformation and body movements. For developing implantable devices with optimised wireless data-path, long battery life, and effective control of field distribution, a thorough understanding of these issues is critical to the future advancement of BSNs.The objective of this proposal is to create a new imaging based subject-specific RF simulation environment for wearable and implantable wireless Body Sensor Networks (BSNs). It brings together a multi-disciplinary team from Imperial College London (ICL) and Queen Mary, University of London (QMUL) with expertise in medical imaging, BSN, electromagnetic modelling, antennas and radio propagation.
 
Description This proposal is concerned with the development of a new imaging based subject specific RF simulation environment for wearable and implantable wireless Body Sensor Networks (BSNs). A thorough understanding of electromagnetics for in vivo radio propagation is critical to the future development of BSNs. This is because the wireless data-path currently constitutes the majority of the power budget and it dictates the level of miniaturization that is achievable for implantable devices and the amount of on-node processing required. It also influences the possible powering methods to be used, i.e., power scavenging for achieving perpetual wireless sensing, or the use of fixed or externally charged batteries.The main findings of the project are:



1. High quality whole-body iRFSim reference database that incorporates dynamic tissue deformation, cardiac and respiratory motion, body articulation and posture changes;

2. Development of an efficient segmentation and registration scheme for the data acquired and construct a dynamic, statistical atlas for the normal subjects studied;

3. An efficient motion modelling scheme based on topological structure and shape warping for inter- and intra-subject iRFSim simulations;

4. Match human tissue datasets with the statistical atlas for different frequencies and obtain frequency-dependent tissue properties using existing Drude/Lorentz models;

5. Combination of dispersive FDTD and conformal FDTD and their parallel implementation for fast and accurate CAD for subject-specific BSN modelling;

6. Validation of the subject specific models using in/on-body propagation measurement with different antenna configurations and phantom experiments, and understanding of radio propagation issues for wireless implants to tackle the trade-offs between accessibility of sensory signals and radio ranges.
Exploitation Route The objective of this proposal is to create a new imaging based subject-specific RF simulation environment for wearable and implantable wireless BSN. It has bought together a multi-disciplinary team from Imperial College London (ICL) and Queen Mary, University of London (QMUL) with expertise in medical imaging, BSN, electromagnetic modelling, antennas and radio propagation. Key technical issues addressed by the project include a whole-body iRFSim reference database, statistical atlas of the human subjects studied for radio propagation simulation, parallel dispersive/conformal FDTD simulation and subject-specific models using in/on-body propagation measurement with different antenna configurations and phantom experiments. The technical issues addressed by the project is valuable for the future development of pervasive healthcare with which continuous monitoring and intelligent decision support for chronic illness will improve the quality of care and facilitate treatment in the community. The main beneficiaries of the project include the research community in BSN, medical imaging, electromagnetic modelling, antennas and radio propagation. The beneficiaries also include patients, healthcare practitioners, NHS, and wireless wearable/implantable device manufacturers. For patients, further development of BSN will allow the early detection of diseases not just for high-risk patients but also for asymptomatic subjects and eventually the general population. The technical issues addressed by the project is fundamental to the future development of pervasive healthcare with which continuous monitoring and intelligent decision support for chronic illness will improve the quality of care and facilitate treatment in the community. For healthcare practitioners, this allows the diagnosis and monitoring not to be limited to the brief time points when the patient is in the hospital, and allow transient abnormalities to be captured at their natural states.



This can provide more detailed insight into the inter-relationship between different physiological and patho-physiological events, permitting more objective assessment and treatment of diseases that are episodic. For the NHS, effective deployment of BSN addresses the need for lowering healthcare costs, maximising efficiency, and reducing hospital stay without compromising patient care. The proposed project is timely in that it responses to the National Institute for Clinical Excellence (NICE) initiative which addresses the unsatisfactory nature of snapshot assessment of patients at arbitrary time points and the increasing future potential for non-invasive and invasive biosensors to aid healthcare. This project will also benefit UK electronics industry for civil and military applications, in particular, system engineers for sensor specification and design engineers for antenna and sensor design.
Sectors Digital/Communication/Information Technologies (including Software),Electronics,Healthcare

URL http://ubimon.doc.ic.ac.uk/RFsim/m673.html
 
Description Body centric wireless communications is now an integral part of mobile communications, particularly for medical sensing applications. Prof. Hao has pioneered this research and provided the industry with an understanding for designing sensors and antenna/radiation components for on-body communications. While off-body propagation has been extensively studied, communication from implanted devices through the human body is a new area of study. Nevertheless, on-body communication is critical when connecting with medical devices, including implanted pacemakers and cardiac defibrillators, wirelessly controlled valves in the urinary tract for on-demand bladder control, and for integrated drug-delivering therapeutic systems (including those for fast acting insulin in diabetics). For these devices, the wireless data-path used to interrogate and communicate with the implants represents one of the most significant research challenges due to high propagation losses and the complex characteristics of the human body. Prof. Hao developed many implantable antennas and characterized their effects using new channel modeling techniques and by integrating computational techniques to account for implantable RFID sensors.
First Year Of Impact 2013
Sector Aerospace, Defence and Marine,Digital/Communication/Information Technologies (including Software),Electronics,Healthcare
Impact Types Societal,Economic

 
Description EPSRC ICT Strategic Advisory Team Member
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
Impact Yang Hao has given advice to EPSRC, BIS and Dstl.
URL https://www.epsrc.ac.uk/research/ourportfolio/themes/ict/strategy/sat/
 
Description EP/I000259/1: Reduction of Energy Demand in Buildings through Optimal Use of Wireless Behaviour Information (Wi-be) Systems
Amount £200,000 (GBP)
Funding ID EP/I000259/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 10/2010 
End 03/2013
 
Description EP/I00923X/1, PATRICIAN: New Paradigms for Body Centric Wireless Communications at MM Wavelengths
Amount £390,988 (GBP)
Funding ID EP/I009019/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2011 
End 07/2014
 
Description Philips Research Laboratories 
Organisation Philips Research Laboratories
Country Netherlands 
Sector Private 
Start Year 2003
 
Title ???? 
Description Disclosed in an embodiment of the present invention is a communication terminal, comprising an antenna which comprises a circuit board, a radiator, a first feed source, a first coupling structure, a second feed source and a second coupling structure. The radiator is disposed around an outer edge of the circuit board and an annular gap is formed between the radiator and the outer edge of the circuit board. The first feed source is electrically connected to the first coupling structure, which is coupled to the radiator in a first direction, and a current in a first polarization direction is formed on the circuit board through the radiator and the annular gap. The second feed source is electrically connected to the second coupling structure, which is coupled to the radiator in a second direction, and a current in a second polarization direction is formed on the circuit board through the radiator and the annular gap, the first direction being at an angle from the second direction. The antenna of the communication terminal has a smaller volume and a higher degree of isolation. 
IP Reference WO2017205998 
Protection Patent application published
Year Protection Granted 2017
Licensed Commercial In Confidence
Impact Commercial in Confidence
 
Title RF ELEMENT 
Description An optically transparent radio frequency or microwave device has first and second optically-transparent conductive substrates. Each carries a respective optically- transparent conductive electrode, and an optically- transparent liquid crystal layer forming a dielectric between the electrodes. The dielectric properties of the liquid crystal layer are controlled by application of a variable bias between the electrodes, to vary a resonant frequency of the device. 
IP Reference WO2011042699 
Protection Patent application published
Year Protection Granted 2011
Licensed Commercial In Confidence
Impact Related work has been used for Ka/Ku satellite antenna applications.
 
Description Mobihealth 2015 conference chair, London. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact The objectives of this conference are to advance medical diagnosis, treatment, and patient care through application of wireless communications, mobile computing and sensing technologies. Contributions will be solicited regarding the interdisciplinary design of efficient technologies and protocols to help implement and provide advanced mobile health care applications. The essence of the conference lies in its interdisciplinary nature, with original contributions cutting across boundaries but all within the ambit of the application of mobile communications (technologies, standards, solutions, methodologies) aiming at the betterment of human health. As such, the conference will have a multi-tier approach, going from in-body sensor devices to ubiquitous patient monitoring environments.
Year(s) Of Engagement Activity 2015
URL http://mobihealth.name/2015/show/cf-papers