PROSPEcT: Ecotoxicology test protocols for representative nanomaterials in support of the OECD sponsorship programme
Lead Research Organisation:
Imperial College London
Department Name: Earth Science and Engineering
Abstract
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People |
ORCID iD |
Mark Rehkamper (Principal Investigator) |
Publications
Mark Rehkamper (Author)
(2010)
Stable Isotope Tracing of Engineered ZnO Nanomaterials
Mark Rehkamper (Author)
(2011)
Stable isotope tracing of engineered CeO2 nanomaterials
Larner F
(2012)
Evaluation of stable isotope tracing for ZnO nanomaterials--new constraints from high precision isotope analyses and modeling.
in Environmental science & technology
Larner F
(2012)
Tracing bioavailability of ZnO nanoparticles using stable isotope labeling.
in Environmental science & technology
Khan FR
(2013)
Stable isotope tracer to determine uptake and efflux dynamics of ZnO Nano- and bulk particles and dissolved Zn to an estuarine snail.
in Environmental science & technology
Laycock A
(2014)
Synthesis and characterization of isotopically labeled silver nanoparticles for tracing studies
in Environ. Sci.: Nano
Larner F
(2014)
An inter-laboratory comparison of high precision stable isotope ratio measurements for nanoparticle tracing in biological samples
in J. Anal. At. Spectrom.
Laycock A
(2016)
Earthworm Uptake Routes and Rates of Ionic Zn and ZnO Nanoparticles at Realistic Concentrations, Traced Using Stable Isotope Labeling.
in Environmental science & technology
Laycock A
(2016)
High precision 142 Ce/ 140 Ce stable isotope measurements of purified materials with a focus on CeO 2 nanoparticles
in Journal of Analytical Atomic Spectrometry
Griffiths A
(2020)
Evaluation of Optimized Procedures for High-Precision Lead Isotope Analyses of Seawater by Multiple Collector Inductively Coupled Plasma Mass Spectrometry.
in Analytical chemistry
Description | This project was part of the large PROSPECT LINK project, which provided the UK contribution to the global safety assessment of nanomaterials described by the OECD Working Party on Manufactured Nanomaterials. The UK contribution was to develop test methods and provide data on two agreed nanomaterials that are of particular commercial relevance to the UK - ZnO and CeO2 nanoparticles. Our particular contribution was the identification and development of new isotopic methods for tracing ZnO and CeO2 nanoparticles in complex natural samples. |
Exploitation Route | The methods that have been developed for isotopic tracing ZnO and CeO2 nanoparticle are in the pubic domain to encourage their use for ecotoxicolligical studies of nanomaterials, which are carried out in both academia and industry. A comprehensive evaluation of isotopic techniques for the tracing of ZnO and CeO2 nanoparticles in complex natural samples was carried out. These evaluations led to the development of preferred isotopic tracing methods that involve the use of isotopically labelled ZnO and CeO2 nanoparticles. These recommendations were published in two PROSPCET Reports for the OECD Working Party on Manufactured Nanomaterials. Amended versions of thes reports have been (ZnO) or will be (CeO2) be published in the scientific literature. |
Sectors | Agriculture, Food and Drink,Chemicals,Environment,Government, Democracy and Justice,Manufacturing, including Industrial Biotechology |
URL | http://www.nanotechia-prospect.org/ |
Description | Findings provide an improved understanding of nanoparticle behavior in the environment. |
First Year Of Impact | 2011 |
Sector | Environment |
Impact Types | Societal,Policy & public services |
Description | Characterization of isotopically labelled 109Ag nanoparticles |
Amount | £24,000 (GBP) |
Funding ID | FENAC/2011/05/004 |
Organisation | Natural Environment Research Council |
Sector | Public |
Country | United Kingdom |
Start | 02/2012 |
End | 01/2013 |
Description | EPSRC Internal Funds - EQUIPMENT SHARING BETWEEN INSTITUTIONS |
Amount | £14,000 (GBP) |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2012 |
End | 03/2013 |
Description | Faculty of Engineering EPSRC Internal Funds - Kick-start for Strategic Priorities |
Amount | £12,000 (GBP) |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2012 |
End | 03/2013 |
Description | Imperial College London |
Amount | £11,750 (GBP) |
Funding ID | EPSRC Internal Funds - Kick-start for Strategic Priorit |
Organisation | Imperial College London |
Sector | Academic/University |
Country | United Kingdom |
Start | 04/2012 |
End | 03/2013 |
Description | Imperial College London |
Amount | £13,075 (GBP) |
Funding ID | EPSRC Equipment Sharing Funds |
Organisation | Imperial College London |
Sector | Academic/University |
Country | United Kingdom |
Start | 04/2012 |
End | 03/2013 |
Description | Metal/Metal Oxide Nanomaterials and Oxidative Stress- Are there Harmful Health Effects in Fish for Environmental Exposures |
Amount | £275,000 (GBP) |
Funding ID | NE/L004968/1 |
Organisation | Natural Environment Research Council |
Sector | Public |
Country | United Kingdom |
Start | 06/2014 |
End | 06/2017 |
Description | NERC Grouped |
Amount | £24,000 (GBP) |
Funding ID | FENAC/2011/05/004 |
Organisation | Natural Environment Research Council |
Sector | Public |
Country | United Kingdom |
Start | 04/2012 |
End | 12/2012 |
Description | Synthesis and Characterization of isotopically labelled 140CeO2 nanoparticles |
Amount | £24,000 (GBP) |
Funding ID | FENAC/2012/11/005 |
Organisation | Natural Environment Research Council |
Sector | Public |
Country | United Kingdom |
Start | 02/2013 |
End | 01/2014 |
Description | Research Collaboration |
Organisation | Natural History Museum |
Country | United Kingdom |
Sector | Public |
PI Contribution | Research collaborations for the development and application of stable isotope labelin technqiues have been developed with the Natural History Museum (Eva Valsami-Jones), University of Birmingham (Jamie Lead) and CEH (Claus Svendsen). |
Start Year | 2011 |
Description | Research Collaboration |
Organisation | UK Centre for Ecology & Hydrology |
Country | United Kingdom |
Sector | Public |
PI Contribution | Research collaborations for the development and application of stable isotope labelin technqiues have been developed with the Natural History Museum (Eva Valsami-Jones), University of Birmingham (Jamie Lead) and CEH (Claus Svendsen). |
Start Year | 2011 |
Description | Research Collaboration |
Organisation | University of Birmingham |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Research collaborations for the development and application of stable isotope labelin technqiues have been developed with the Natural History Museum (Eva Valsami-Jones), University of Birmingham (Jamie Lead) and CEH (Claus Svendsen). |
Start Year | 2011 |