Core capability for Chemistry Research
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The National Importance of a vibrant and successful university Chemistry research sector cannot be underestimated. The RSC's report on the Economic Benefits of Chemistry showed that the UK's upstream chemicals industry and downstream chemistry-using sectors contributed a combined total of £258 billion in added-value in 2007, equivalent to 21% of UK GDP, and supported over 6 million UK jobs. This output is underpinned by some of the world's most successful University Chemistry research, reflecting the fruits of many years of investment. On-going fundamental research is essential, not only to maintain a continuing flow of scientific and technological breakthroughs, but also to ensure that the UK maintains a highly skilled and innovative workforce; it is through these trained people that the UK will adopt and advance new ideas, successfully exploit new technologies, and develop new and better products and services. The ability to develop and exploit chemically-derived technology will fuel economic activity, and is a necessary condition for attracting inward investment to the UK. The RSC report also showed that the quality of UK chemists and the reputation for excellence of the UK's university chemical science base significantly influences companies in decisions to locate within the UK, or to retain a UK-based research presence.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Planned Impact
Please see Pathways to Impact
Organisations
Publications
Elani Y
(2015)
Vesicle-based artificial cells: recent developments and prospects for drug delivery.
in Therapeutic delivery
Elani Y
(2015)
Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors.
in Physical chemistry chemical physics : PCCP
Evans HL
(2014)
Bioorthogonal chemistry for (68) Ga radiolabelling of DOTA-containing compounds.
in Journal of labelled compounds & radiopharmaceuticals
Fajardo OY
(2015)
Electrotunable lubricity with ionic liquid nanoscale films.
in Scientific reports
Fallon K
(2015)
A Nature-Inspired Conjugated Polymer for High Performance Transistors and Solar Cells
in Macromolecules
Fei Z
(2015)
Influence of Backbone Fluorination in Regioregular Poly(3-alkyl-4-fluoro)thiophenes
in Journal of the American Chemical Society
Fei Z
(2015)
Diselenogermole as a novel donor monomer for low band gap polymers
in Journal of Materials Chemistry A
Forster M
(2015)
Oxygen deficient a-Fe2O3 photoelectrodes: a balance between enhanced electrical properties and trap-mediated losses.
in Chemical science
Freedman KJ
(2016)
Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping.
in Nature communications
Freedman KJ
(2014)
Nonequilibrium capture rates induce protein accumulation and enhanced adsorption to solid-state nanopores.
in ACS nano
Furse S
(2015)
Synthesis of unsaturated phosphatidylinositol 4-phosphates and the effects of substrate unsaturation on SopB phosphatase activity.
in Organic & biomolecular chemistry
Gallina ME
(2016)
Aptamer-conjugated, fluorescent gold nanorods as potential cancer theradiagnostic agents.
in Materials science & engineering. C, Materials for biological applications
Ghosh S
(2014)
Assembly of palladium(II) and platinum(II) metallo-rectangles with a guanosine-substituted terpyridine and study of their interactions with quadruplex DNA.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Gibb TR
(2014)
Single molecule ionic current sensing in segmented flow microfluidics.
in Analytical chemistry
Giovannitti A
(2015)
Sodium and Potassium Ion Selective Conjugated Polymers for Optical Ion Detection in Solution and Solid State
in Advanced Functional Materials
Godfrey D
(2016)
A robotic platform for high-throughput electrochemical analysis of chalcopyrite leaching
in Green Chemistry
Gomes H
(2015)
All-inkjet printed organic transistors: Dielectric surface passivation techniques for improved operational stability and lifetime
in Microelectronics Reliability
Gong X
(2014)
Label-free in-flow detection of single DNA molecules using glass nanopipettes.
in Analytical chemistry
Gonzalez MA
(2015)
Bubble nucleation in simple and molecular liquids via the largest spherical cavity method.
in The Journal of chemical physics
Govada L
(2016)
Exploring Carbon Nanomaterial Diversity for Nucleation of Protein Crystals.
in Scientific reports
Grau M
(2014)
Ligand tuning of single-site manganese-based catalytic antioxidants with dual superoxide dismutase and catalase activity.
in Chemical communications (Cambridge, England)
Greenhalgh E
(2014)
Mechanical, electrical and microstructural characterisation of multifunctional structural power composites
in Journal of Composite Materials
Haywood T
(2014)
Microfluidic Hydrogenation Reactions by using a Channel-Supported Rhodium Catalyst
in ChemCatChem
He Y
(2015)
Dynamic Charge Storage in Ionic Liquids-Filled Nanopores: Insight from a Computational Cyclic Voltammetry Study.
in The journal of physical chemistry letters
Hill PJ
(2015)
H2 activation by a highly electron-deficient aralkylated organoborane.
in Dalton transactions (Cambridge, England : 2003)
Holliday S
(2015)
A rhodanine flanked nonfullerene acceptor for solution-processed organic photovoltaics.
in Journal of the American Chemical Society
Hu Y
(2015)
Ruthenium Dyes with Azo Ligands: Light Harvesting, Excited-State Properties and Relevance to Dye-Sensitised Solar Cells
in European Journal of Inorganic Chemistry
Hurtubise VL
(2014)
Multimetallic complexes and functionalized nanoparticles based on unsymmetrical dithiocarbamate ligands with allyl and propargyl functionality.
in Inorganic chemistry
Hutton JA
(2014)
Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors.
in Journal of medicinal chemistry
Ivanov AP
(2015)
On-demand delivery of single DNA molecules using nanopipets.
in ACS nano
Ivanov AP
(2014)
High precision fabrication and positioning of nanoelectrodes in a nanopore.
in ACS nano
Izquierdo MA
(2015)
Dual use of porphyrazines as sensitizers and viscosity markers in photodynamic therapy.
in Journal of materials chemistry. B
Ja'afar F
(2015)
Surface Charge Measurement of SonoVue, Definity and Optison: A Comparison of Laser Doppler Electrophoresis and Micro-Electrophoresis.
in Ultrasound in medicine & biology
Japrung D
(2014)
SSB binding to single-stranded DNA probed using solid-state nanopore sensors.
in The journal of physical chemistry. B
Jenkins S
(2014)
The response of the electronic structure to electronic excitation and double bond torsion in fulvene: a combined QTAIM, stress tensor and MO perspective.
in Physical chemistry chemical physics : PCCP
Kakati B
(2014)
Gas phase recovery of hydrogen sulfide contaminated polymer electrolyte membrane fuel cells
in Journal of Power Sources
Kang DK
(2015)
3D Droplet Microfluidic Systems for High-Throughput Biological Experimentation.
in Analytical chemistry
Karamdad K
(2015)
Preparation and mechanical characterisation of giant unilamellar vesicles by a microfluidic method.
in Lab on a chip
Kim J
(2015)
Morphology-performance relationships in polymer/fullerene blends probed by complementary characterisation techniques - effects of nanowire formation and subsequent thermal annealing
in Journal of Materials Chemistry C
Krausbeck F
(2014)
Choosing RASSCF orbital active spaces for multiple electronic states
in Computational and Theoretical Chemistry
Kumar S
(2016)
Template-Stripped Multifunctional Wedge and Pyramid Arrays for Magnetic Nanofocusing and Optical Sensing.
in ACS applied materials & interfaces
Lawrance D
(2015)
Development of a disposable bile acid biosensor for use in the management of cholestasis
in Analytical Methods
Lawrence EJ
(2015)
A combined "electrochemical-frustrated lewis pair" approach to hydrogen activation: surface catalytic effects at platinum electrodes.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Le TT
(2014)
Aptamer-based biosensors for the rapid visual detection of flu viruses.
in Chemical communications (Cambridge, England)
Leese HS
(2016)
Reductively PEGylated carbon nanomaterials and their use to nucleate 3D protein crystals: a comparison of dimensionality.
in Chemical science
Lin XM
(2015)
Highlights of the Faraday Discussion on Nanoparticle Synthesis and Assembly, Argonne, USA, April 2015.
in Chemical communications (Cambridge, England)
Description | Chemistry is the study and application of the science at the molecular scale. It provides some of the most basic understandings of how the world works and underpins many modern technologies. It provides both the most mundane of objects, such as the disposable cup that holds you coffee, and the most vital compounds, such as life-saving drugs. Chemistry relies on four core instrumental techniques to study molecules; Nuclear Magnetic Resonance, Mass Spectrometry, X-Ray Crystallography and molecular scale Microscopy. This grant gave the Chemistry Department at Imperial College the ability to update these facilities. These have enabled research in all areas of Chemistry, for example the building of artificial cells, the production of fuels from biomass to the development of new potential pharmaceuticals and diagnostic techniques. There are too many to list. |
Exploitation Route | There are many ways in which these results can be put to use in the wider world. |
Sectors | Aerospace, Defence and Marine,Agriculture, Food and Drink,Chemicals,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Culture, Heritage, Museums and Collections,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy,Transport |
Description | Policy Briefing Document |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Author of policy briefing document: Using Carbon Dioxide |
Year(s) Of Engagement Activity | 2017 |
Description | Presentation to stakeholders |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Laura Barter was invited to the World Economic Forum in Davos to present her research investigating methods for increasing crop yields by promoting more efficient photosynthesis in the session on "Engineering Intelligent Food Systems". |
Year(s) Of Engagement Activity | 2018 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | BBC World Service's The Why Factor (8 February) on "Why is Water Exceptional?" |
Year(s) Of Engagement Activity | 2016 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Andrew Ashley interviewed on BBC Radio 4's Inside Science explaining his group's recent discovery in N2 fixation |
Year(s) Of Engagement Activity | 2016 |
Description | Schools activity |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Schools |
Results and Impact | Salters Festival of Chemistry: Annual Salters Festival. Y7 and Y8 many schools attend with their teachers to undertake two chemistry-based challenges |
Year(s) Of Engagement Activity | 2018 |
Description | Stakeholder meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Laura Barter, Rudiger Wolcholski and Sarah Al-Beidh organised a Creativity and Ideas generation event for the Sainsbury's farming scholars which was also attended by Sainsbury's horticulture manager, academics from Imperial, Natural History Museum and other UK institutions. Followed by attending the Annual Sainsbury's Farming Conference to highlight the success of the Sainsbury's Farming Scholars Programme - a recent collaboration between Imperial College, AGRI-net and Sainsbury's. |
Year(s) Of Engagement Activity | 2015,2016 |
Description | UK Chemicals Stakeholder Forum. Presentation on measuring sustainability |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | Presentation and discussion on sustainability metrics |
Year(s) Of Engagement Activity | 2016 |
Description | World Economic Forum meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Prof David Klug introduced the "Hyperconnected Healthcare" panel at the World Economic Forum meeting in Dalian and participated as a panel member. |
Year(s) Of Engagement Activity | 2015 |