Maximising patient benefit: Leeds’ Interdisciplinary approach to translation
Lead Research Organisation:
University of Leeds
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.
Organisations
People |
ORCID iD |
Paul Stewart (Principal Investigator) |
Publications
Ye S
(2019)
Sub-Nanometer Thick Gold Nanosheets as Highly Efficient Catalysts.
in Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ye S
(2020)
Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells.
in Small (Weinheim an der Bergstrasse, Germany)
Ye S
(2019)
Sub-Nanometer Thick Gold Nanosheets: Sub-Nanometer Thick Gold Nanosheets as Highly Efficient Catalysts (Adv. Sci. 21/2019)
in Advanced Science
Ye S
(2020)
One-Step Preparation of Biocompatible Gold Nanoplates with Controlled Thickness and Adjustable Optical Properties for Plasmon-Based Applications
in Advanced Functional Materials
Weigel M
(2017)
Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer.
in Clinical endocrinology
Tanaka M
(2019)
Rational screening of biomineralisation peptides for colour-selected one-pot gold nanoparticle syntheses
in Nanoscale Advances
Stewart PM
(2016)
Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency.
in The Journal of clinical endocrinology and metabolism
Shawer H
(2021)
ORAI1 Ca2+ Channel as a Therapeutic Target in Pathological Vascular Remodelling.
in Frontiers in cell and developmental biology
Rode B
(2018)
ORAI Channels as Potential Therapeutic Targets in Pulmonary Hypertension.
in Physiology (Bethesda, Md.)
Robinson JI
(2018)
Affimer proteins inhibit immune complex binding to Fc?RIIIa with high specificity through competitive and allosteric modes of action.
in Proceedings of the National Academy of Sciences of the United States of America
Roach L
(2018)
Corrigendum: Morphological control of seedlessly-synthesized gold nanorods using binary surfactants (2018 Nanotechnology 29 135601).
in Nanotechnology
Roach L
(2018)
Morphological control of seedlessly-synthesized gold nanorods using binary surfactants.
in Nanotechnology
Rakic A
(2019)
Sensing and imaging using laser feedback interferometry with quantum cascade lasers
in Applied Physics Reviews
Morgan SA
(2016)
Glucocorticoids and 11ß-HSD1 are major regulators of intramyocellular protein metabolism.
in The Journal of endocrinology
Moorcroft SCT
(2020)
Nanoparticle-Loaded Hydrogel for the Light-Activated Release and Photothermal Enhancement of Antimicrobial Peptides.
in ACS applied materials & interfaces
Lim YL
(2019)
Coherent imaging using laser feedback interferometry with pulsed-mode terahertz quantum cascade lasers.
in Optics express
Larner DP
(2016)
Male 11ß-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.
in Endocrinology
Kirkby CJ
(2021)
Developing a Raman spectroscopy-based tool to stratify patient response to pre-operative radiotherapy in rectal cancer.
in The Analyst
Keeley J
(2019)
Detection sensitivity of laser feedback interferometry using a terahertz quantum cascade laser.
in Optics letters
Kearney K
(2021)
Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI
in Proceedings of the National Academy of Sciences
Jenkinson C
(2016)
High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum.
in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Hepburn S
(2015)
An analysis of the impact of pre-analytical factors on the urine proteome: Sample processing time, temperature, and proteolysis.
in Proteomics. Clinical applications
Hardy RS
(2016)
11ß-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.
in The Journal of pathology
Description | Flight |
Amount | £8,484 (GBP) |
Organisation | The ITP Support Association |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 10/2020 |
End | 09/2021 |
Description | HyperTerahertz - High precision terahertz spectroscopy and microscopy |
Amount | £6,517,861 (GBP) |
Funding ID | EP/P021859/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2017 |
End | 05/2022 |
Description | Optimising the affinity and format of a lead candidate biotherapeutic for the treatment of immune thrombocytopenia |
Amount | £28,576 (GBP) |
Funding ID | M866 |
Organisation | Rosetrees Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2019 |
End | 08/2022 |
Description | The impact of Fc gamma receptor polymorphisms on treatment response in adult patients with primary immune thrombocytopenia |
Amount | £25,992 (GBP) |
Organisation | British Medical Association (BMA) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2017 |
End | 09/2021 |