Maximising patient benefit: Leeds’ Interdisciplinary approach to translation
Lead Research Organisation:
University of Leeds
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.
Organisations
People |
ORCID iD |
Paul Stewart (Principal Investigator) |
Publications
Crowley RK
(2016)
SFRP2 Is Associated with Increased Adiposity and VEGF Expression.
in PloS one
Kearney K
(2021)
Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI
in Proceedings of the National Academy of Sciences
Robinson JI
(2018)
Affimer proteins inhibit immune complex binding to Fc?RIIIa with high specificity through competitive and allosteric modes of action.
in Proceedings of the National Academy of Sciences of the United States of America
Hepburn S
(2015)
An analysis of the impact of pre-analytical factors on the urine proteome: Sample processing time, temperature, and proteolysis.
in Proteomics. Clinical applications
Dineen R
(2017)
Acromegaly.
in QJM : monthly journal of the Association of Physicians
Armistead FJ
(2020)
Physical Biomarkers of Disease Progression: On-Chip Monitoring of Changes in Mechanobiology of Colorectal Cancer Cells.
in Scientific reports
Ye S
(2020)
Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells.
in Small (Weinheim an der Bergstrasse, Germany)
Bao P
(2021)
Production of giant unilamellar vesicles and encapsulation of lyotropic nematic liquid crystals
in Soft Matter
Gala De Pablo J
(2020)
Detection and time-tracking activation of a photosensitiser on live single colorectal cancer cells using Raman spectroscopy.
in The Analyst
Kirkby CJ
(2021)
Developing a Raman spectroscopy-based tool to stratify patient response to pre-operative radiotherapy in rectal cancer.
in The Analyst
Description | Flight |
Amount | £8,484 (GBP) |
Organisation | The ITP Support Association |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 10/2020 |
End | 09/2021 |
Description | HyperTerahertz - High precision terahertz spectroscopy and microscopy |
Amount | £6,517,861 (GBP) |
Funding ID | EP/P021859/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2017 |
End | 05/2022 |
Description | Optimising the affinity and format of a lead candidate biotherapeutic for the treatment of immune thrombocytopenia |
Amount | £28,576 (GBP) |
Funding ID | M866 |
Organisation | Rosetrees Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2019 |
End | 08/2022 |
Description | The impact of Fc gamma receptor polymorphisms on treatment response in adult patients with primary immune thrombocytopenia |
Amount | £25,992 (GBP) |
Organisation | British Medical Association (BMA) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2017 |
End | 09/2021 |