Experimental Medicine INitiative to Explore New Therapies (EMINENT) network training programme
Lead Research Organisation:
University of Cambridge
Department Name: UNLISTED
Abstract
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Technical Summary
Experimental medicine lies at the core of MRC translational research strategy, translating basic scientific discovery into benefits for human health. Delivering effective experimental medicine requires the involvement of clinicians and scientists with bespoke skills sets; integrating mechanistic disease insight with experience of drug development and clinical trial design, for which a critical skills gap has been identified by the MRC. A key objective of EMINENT is to address this skills gap with the specific aim to ‘Develop a cohort of excellence in experimental medicine, through targeted training for early career scientists and fellows’. This cohort of clinical and non-clinical scientists, will be unique within the UK, and consist of individuals who will have the aptitude, training, experience and skill set to allow them to work between academia and the pharmaceutical industry to deliver high quality, integrated experimental medicine studies and early phase clinical trials. To capitalize on the opportunity created by EMINENT, the MRC, GSK and five partnership Universities (UCL, Glasgow, Cambridge, Newcastle and Imperial), together with the NIHR, wish to establish a formal EMINENT Training Programme in which all EMINENT-funded technical, post-doctoral and clinical research staff, will be expected to participate. This includes the additional five NIHR-BRC and GSK funded Clinical Research Fellowship posts, which will be established at Cambridge, UCL, Imperial, Newcastle and (with EMINENT support) Glasgow University.
| Description | Collaboration with GlaxoSmithKline |
| Organisation | GlaxoSmithKline (GSK) |
| Department | Research and Development GSK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | This programme grant is via the MRC-GSK EMINENT network. Alongside the programme is a GSK-NIHR BRC co-funded PhD clinical research training fellowship. |
| Collaborator Contribution | GSK have provided expertise, technical support, compounds, training and hosting of research team members. The research fellow has spent 6 months FTE embedded at GSK R&D. |
| Impact | Follow-on funding is pending. Publications about to be submitted, |
| Start Year | 2018 |
| Description | Training network collaboration (Cambridge, UCL, Imperial, Newcastle, Glasgow). |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I am the Training Programme Director of the EMINENT Research Training Network (which is supported by this funding). |
| Collaborator Contribution | Since 2018, we have placed five clincial research training fellows at UCL, Imperial, Cambridge, Glasgow and Newcastle, with placements at GSK during their fellowships. Alongside their PhDs, they have received a bespoke training programme (designed by me) to support them in developing into the next generation of experimental medicine leader, which has included training from GSK in medicines development, leadership training (also offered to other MRC supported training fellows in experimental medicine).. etc. |
| Impact | Five completed PhDs. |
| Start Year | 2018 |
| Description | Training network collaboration (Cambridge, UCL, Imperial, Newcastle, Glasgow). |
| Organisation | Newcastle University |
| Country | United Kingdom |
| PI Contribution | I am the Training Programme Director of the EMINENT Research Training Network (which is supported by this funding). |
| Collaborator Contribution | Since 2018, we have placed five clincial research training fellows at UCL, Imperial, Cambridge, Glasgow and Newcastle, with placements at GSK during their fellowships. Alongside their PhDs, they have received a bespoke training programme (designed by me) to support them in developing into the next generation of experimental medicine leader, which has included training from GSK in medicines development, leadership training (also offered to other MRC supported training fellows in experimental medicine).. etc. |
| Impact | Five completed PhDs. |
| Start Year | 2018 |
| Description | Training network collaboration (Cambridge, UCL, Imperial, Newcastle, Glasgow). |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I am the Training Programme Director of the EMINENT Research Training Network (which is supported by this funding). |
| Collaborator Contribution | Since 2018, we have placed five clincial research training fellows at UCL, Imperial, Cambridge, Glasgow and Newcastle, with placements at GSK during their fellowships. Alongside their PhDs, they have received a bespoke training programme (designed by me) to support them in developing into the next generation of experimental medicine leader, which has included training from GSK in medicines development, leadership training (also offered to other MRC supported training fellows in experimental medicine).. etc. |
| Impact | Five completed PhDs. |
| Start Year | 2018 |
| Description | Training network collaboration (Cambridge, UCL, Imperial, Newcastle, Glasgow). |
| Organisation | University of Glasgow |
| Department | College of Medical, Veterinary and Life Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I am the Training Programme Director of the EMINENT Research Training Network (which is supported by this funding). |
| Collaborator Contribution | Since 2018, we have placed five clincial research training fellows at UCL, Imperial, Cambridge, Glasgow and Newcastle, with placements at GSK during their fellowships. Alongside their PhDs, they have received a bespoke training programme (designed by me) to support them in developing into the next generation of experimental medicine leader, which has included training from GSK in medicines development, leadership training (also offered to other MRC supported training fellows in experimental medicine).. etc. |
| Impact | Five completed PhDs. |
| Start Year | 2018 |