CiC#5: Furthering the potential for healthcare benefits from the University of Nottingham’s novel early-stage interdisciplinary biomedical research

Lead Research Organisation: University of Nottingham
Department Name: UNLISTED

Abstract

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Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding.  It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

People

ORCID iD
 
Description A Feasibility Trial of Neuromodulation with Connectivity-Guided Intermittent Theta Burst Stimulation for Cognitive Impairment in MS
Amount £244,826 (GBP)
Funding ID Can specialised magnets improve cognition in MS? 
Organisation Multiple Sclerosis Society 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2020 
End 12/2022
 
Description Identification and Characterisation of the Phage and Host Receptors in Clostridium difficile, a Prequisite for Future Phage Therapies
Amount £37,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2018 
End 09/2022
 
Description Miniaturized portable MRI sensors for healthcare applications
Amount £30,000 (GBP)
Organisation Russian Foundation for Basic Research 
Sector Academic/University
Country Russian Federation
Start  
 
Description Towards miniaturised MRI based sodium sensors for healthcare applications
Amount £20,333 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2019 
End 12/2021
 
Title ANTIBACTERIAL COMPOUNDS 
Description Novel compounds having antimicrobial activitiy, in particular against Pseudomonas aeruginosa, Burkholderia cepaciaand/or Clostridium difficile, and a pharmaceutical composition containing the novel compound. 
IP Reference WO2018167506 
Protection Patent application published
Year Protection Granted 2018
Licensed No
Impact Has been awarded £2.05 miliion through the MRC DPFS scheme to translate the technology further
 
Title MATERIALS CHEMISTRIES AND MICROTOPOGRAPHIES AND USES THEREOF 
Description A microtopography system for modulating one or more cellular processes on a surface is described. In particular a microtopography system comprising: a repeated microtopographic pattern and a polymer coating, said microtopographic pattern comprising: an array of repeated micropillars applied to a surface of a product, said micropillars being formed of surface structures between 1-100 µm in height, and 1-50 µm in width; and said polymer coating comprising one of a (meth)acrylate or (meth)acrylamide monomer, or mixture of two (meth)acrylate or (meth)acrylamide monomers.The microtopographic pattern and said polymer coating act to modulate one or more cellular processes on the surface. 
IP Reference WO2021161290 
Protection Patent application published
Year Protection Granted 2021
Licensed No
Impact None yet