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Imaging Centre (Bristol)

Lead Research Organisation: UK Biobank
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The award is in support of a fourth Imaging Centre to complement the three centres already in existence and is designed to accelerate the imaging of the 100,000 UK Biobank participants. Including the repeat imaging of 10,000 participants funded by Dementias Platform UK. Along with the existing centres, the Bristol imaging centre will further provide data to help identify the earliest (pre-clinical) manifestations of dementia, supporting the development and testing of dementia interventions. The standard suite of brain and body measures (using the same protocols), as used for the 100,000 imaging project, will be used for the repeat imaging of 10,000 participants.

Publications

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Conroy M (2022) UK Biobank: a globally important resource for cancer research in British Journal of Cancer

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Foster PJ (2023) Cohort profile: rationale and methods of UK Biobank repeat imaging study eye measures to study dementia. in BMJ open

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He D (2023) A longitudinal genome-wide association study of bone mineral density mean and variability in the UK Biobank. in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

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Leonardsen EH (2023) Genetic architecture of brain age and its causal relations with brain and mental disorders. in Molecular psychiatry

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Luettich A (2023) Functional connectivity between interoceptive brain regions is associated with distinct health-related domains: A population-based neuroimaging study in Human Brain Mapping

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Rutter C (2023) Exploring regression dilution bias using repeat measurements of 2858 variables in =49 000 UK Biobank participants in International Journal of Epidemiology

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Topiwala A (2023) Telomere length and brain imaging phenotypes in UK Biobank. in PloS one

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Ward J (2023) Head motion in the UK Biobank imaging sub-sample: longitudinal stability, associations with psychological and physical health, and risk of non-useable data

 
Description Impact of clinically silent atrial fibrillation on cerebrovascular disease and cognitive decline in the UK Biobank Imaging Cohort
Amount £2,474,260 (GBP)
Funding ID RG/18/6/33576 
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2019 
End 06/2024
 
Description UK Biobank - The Repeat Imaging Project
Amount £2,500,000 (GBP)
Funding ID R39738/CN039 
Organisation MRC Dementias Platform UK 
Sector Academic/University
Country United Kingdom
Start 03/2019 
End 01/2023
 
Description UK Biobank participant imaging event 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact UK Biobank for participants of the imaging work
Year(s) Of Engagement Activity 2021