Driving innovation for human health at Edinburgh
Lead Research Organisation:
University of Edinburgh
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept (CIC) scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions to flexibly support a portfolio of early stage translational research projects. CIC is designed to accelerate the transition from discovery research to viable translational projects by supporting preliminary studies to establish proof-of-concept so that the approach will then become competitive for more substantial translational funding.
Organisations
- University of Edinburgh (Lead Research Organisation)
- Tactuum (Collaboration)
- Centre for Process Innovation (CPI) (Collaboration)
- Aga Khan University (Collaboration)
- Brainsview Inc (Collaboration)
- NHS Lothian (Collaboration)
- Fixed phage limited (Collaboration)
- Queen Astrid Military Hospital (Collaboration)
- DyNAbind GbmH (Collaboration)
- Causeway Therapeutics (Collaboration)
- Digital Health Institute (DHI) (Collaboration)
- UNIVERSITY OF STRATHCLYDE (Collaboration)
People |
ORCID iD |
| Charles Ffrench-Constant (Principal Investigator) |
Publications
Abdullateef S
(2022)
Quantitative detection of seizures with minimal-density EEG montage using phase synchrony and cross-channel coherence amplitude in critical care.
in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Clarke AL
(2020)
The Safety and Efficacy of Phage Therapy for Bone and Joint Infections: A Systematic Review.
in Antibiotics (Basel, Switzerland)
Jones JD
(2023)
Managing Patient and Clinician Expectations of Phage Therapy in the United Kingdom.
in Antibiotics (Basel, Switzerland)
Jones JD
(2022)
The practical, ethical and legal reasons why patients should not be transferred between NHS trusts for phage therapy.
in Journal of patient safety and risk management
Jones JD
(2022)
The potential of bacteriophage therapy in the treatment of paediatric respiratory infections.
in Paediatric respiratory reviews
Jones JD
(2023)
The Future of Clinical Phage Therapy in the United Kingdom.
in Viruses
Macdonald KE
(2020)
Patient perceptions of phage therapy for diabetic foot infection.
in PloS one
Macdonald KE
(2021)
The microbiology of diabetic foot infections: a meta-analysis.
in BMC infectious diseases
| Description | A Window in the Brain |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Training for NHS traineers on detecting seizures in children which will increase survival rates and quality of life. |
| Description | A Window in the Brain |
| Geographic Reach | Europe |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Any changes to practice will improve the healthcare outcomes of the patient |
| Description | A Window in the Brain |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | Dr. Lo is appointed an independent member of the scientific committee for CHIMERA (Collaborative Health Care Innovation Through Mathematics, EngineeRing and AI) based in University College London |
| Description | Evidence provided to House of Commons Science and Tech Select Committee |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| URL | https://committees.parliament.uk/work/7045/the-antimicrobial-potential-of-bacteriophages/publication... |
| Description | Independent member of scientific committee for CHIMERA |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Training material created |
| Geographic Reach | Europe |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | A Cyber-Physical System for Unified Diagnosis and Treatment of Lung Diseases |
| Amount | £1,083,338 (GBP) |
| Funding ID | MR/T023252/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2020 |
| End | 04/2024 |
| Description | EPSRC Capital Core Equipment Award 2020 |
| Amount | £609,322 (GBP) |
| Funding ID | EP/V034995/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2020 |
| End | 05/2022 |
| Description | Institutional Strategic Support Fund - Public Engagement Fund |
| Amount | £1,500 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 06/2022 |
| Description | Josh Jones: Proximity to Discovery Training course |
| Amount | £5,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2020 |
| End | 11/2020 |
| Description | Plug and play: an innovative bio-artificial artery for vascular reconstruction |
| Amount | £380,878 (GBP) |
| Funding ID | MR/V029827/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2021 |
| End | 07/2024 |
| Description | Project Grant |
| Amount | £20,208 (GBP) |
| Organisation | Edinburgh Children's Hospital Charity |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Response Mode Grant |
| Amount | £298,740 (GBP) |
| Funding ID | TCS/21/30 |
| Organisation | Chief Scientist Office |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2022 |
| End | 05/2025 |
| Description | StopCovid |
| Amount | £2,000,000 (GBP) |
| Organisation | LifeArc |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Tayside Health Fund |
| Amount | £202,508 (GBP) |
| Organisation | Tayside Health Board |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2022 |
| Description | Tayside Health Fund Charity - Jones |
| Amount | £159,825 (GBP) |
| Organisation | NHS Tayside |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 02/2023 |
| Description | Usher Institute small grant |
| Amount | £1,000 (GBP) |
| Organisation | University of Edinburgh |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2022 |
| End | 06/2023 |
| Description | WT-ITPA (Jones) |
| Amount | £3,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | WT-ITPA (Jones) |
| Amount | £3,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | WT-ITPA Springboard (Jones) |
| Amount | £5,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Wellcome ITPA (Pinnock) |
| Amount | £5,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Title | Detecting seizures using brain connectivity calculation on as few a 4-channeles EEG |
| Description | We are the first to successfully and accurately detect seizures using brain connectivity calculation on as few as 4-channels EEG, a configuration that may be readily applied by the bedside PICU clinical team without expert input. This was done by adapting the BrainsView seizure detection algorithm by adding an extra feature extraction method (cross-channel amplitude coherence) to its existing phase synchronisation calculation. This enhanced seizure detection performance. We will publish this novel seizure detection method as a technical paper and a clinical utility paper. The anonymised paediatric EEG extracted from Edinburgh Sick Children's Hospital used in this study allows us to start a new anonymised paediatric specific EEG database. With A Window in the Brain 2, we will then establish the first multi-centre paediatric specific anonymised EEG database for research and innovation development |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2022 |
| Provided To Others? | No |
| Impact | We will publish this novel seizure detection method as a technical paper and a clinical utility paper. |
| Title | Rapid-Solution-of-Cosserat-Equations |
| Description | Development of a mathematical model for simulating flexible robots. The model is open-sourced and published online at https://github.com/SIRGLab/Rapid-Solution-of-Cosserat-Equations |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| Impact | Nothing to report yet |
| URL | https://github.com/SIRGLab/Rapid-Solution-of-Cosserat-Equations |
| Description | A Window in the Brain |
| Organisation | NHS Lothian |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Dr. Lo, Dr. Escudero, and Dr. Nenadovic have established and solidified an outstanding academic-clinical-industry partnership through and will continue to collaborate after this CiC project. Dr. Lo brought specialist medical knowledge and research leadership to the project. Dr. Lo additionally oversaw EEG data access within PICU and paediatric neuroscience department in NHS Lothian. Dr Escudero brought to this partnership his substantial experience in processing routinely collected paediatric EEG, EEG functional connectivity, and the creation of fast metrics to analysis biomedical signals. He contributed significantly to the adaptation of EEG functional connectivity assessment methods to low-density EEG set-ups. Dr. Nenadovic brought to the project her knowledge and skills in industry development and engagement in critical care nurses in clinical translations of novel technologies through her roles respectively as the Founder and Scientific Director of Brainsview Inc. and a practising advanced nurse practitioner in paediatric rehabilitation in Canada. In addition, Dr. Nenadovic provided in kind support (£51k equivalent) of her time and software development support during this CiC project. Drs. Lo / Escudero / Nenadovic continue this dynamic and successful academic-clinical-industry partnership beyond this CiC project. They have jointly submitted a grant application to the CSO for funding for A Window in the Brain 2 to further refine our innovation in a multi-centre setting. They are currently building another grant application to the MRC to support KidsBrainIT-2 which will involve new collaborations with Lower Middle Income Countries (LMIC) including Pakistan and South Africa. We have established another NHS collaboration, arising from this CiC project with Dr. McLellan, a consultant paediatric neurologist, and Brian Jordan, a clinical neurophysiologist based in Royal Hospital for Children and Young People in Edinburgh. They have provided domain expertise in clinical and neurophysiological seizure detections and epilepsy to our CiC project. Dr. McLellan is a co-applicant in our CSO application for A Window in the Brain 2 and will ensure our innovation is validated against expert the gold standard seizure detection. This provides an additional competitive advantage over our existing competitions in the bedside non-expert seizure detection market. We have additionally established a new collaboration with a paediatric intensivist (Dr. Qalab Abbas) and a paediatric neurologist (Dr. Sidra Kaleem) in Karachi, Pakistan. Dr. Escudero and Dr. Nenadovic plan to jointly apply for the Universities of Toronto and Edinburgh seed funding with them to explore the clinical application of our innovation in a LMIC setting. |
| Collaborator Contribution | as above |
| Impact | Grant applications submitted |
| Start Year | 2019 |
| Description | A window in the Brain |
| Organisation | Aga Khan University |
| Country | Pakistan |
| Sector | Academic/University |
| PI Contribution | We have additionally established a new collaboration with a paediatric intensivist (Dr. Qalab Abbas) and a paediatric neurologist (Dr. Sidra Kaleem) in Karachi, Pakistan We provide the research project ideas and previous work. |
| Collaborator Contribution | Clinical expertise |
| Impact | Applying for grant funding |
| Start Year | 2021 |
| Description | CIC Round 7 Andrea Caporali |
| Organisation | Causeway Therapeutics |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | The project lead is an inventor on the UK provisional patent application (April 18) and a PCT application (April 2019) on the role of miR-148B on diabetic foot ulcers, which underpins this project. The project lead has brought in expertise and the development partner in the form of Causeway Therapeutics. |
| Collaborator Contribution | Project has received significant commercial input from the CEO and CSO or Causeway Therapeutics, the development partner of the project. |
| Impact | No outputs to date as the project is still live. |
| Start Year | 2019 |
| Description | CIC Round 7 Hilary Pinnock |
| Organisation | Digital Health Institute (DHI) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Project lead, Hilary Pinnock, brought in the DHI to provide essential support to her commercial project. |
| Collaborator Contribution | CTO in the Digital Health and Care Institute will support the free access to their data exchange API and platform to connect the project app with the IoT (internet of things) devices in the market. They will also provide untethered aggregator Personal Health Record funtionality as defined by NHS Digital. |
| Impact | No outputs as project is still live. |
| Start Year | 2019 |
| Description | CIC Round 7 Hilary Pinnock |
| Organisation | Tactuum |
| Country | United States |
| Sector | Private |
| PI Contribution | The project lead, Hilary Pinnock, identified the need for an asthma app to link flexibly with multiple existing technologies to provide seamless support to patients. |
| Collaborator Contribution | Tactuum will provide 4 staff members covering: UI/UX design, development and testing. Contributing to the delivery of all milestones. £44k in kind contribution. Tactuum will build a Minimal Viable Product (MVP) platform supporting the collections of data via a 'connected' asthma app' and devices. |
| Impact | No outputs to date as the project is still active. |
| Start Year | 2019 |
| Description | CIC Round 7 Hilary Pinnock |
| Organisation | Tactuum |
| Country | United States |
| Sector | Private |
| PI Contribution | The project lead, Hilary Pinnock, identified the need for an asthma app to link flexibly with multiple existing technologies to provide seamless support to patients. |
| Collaborator Contribution | Tactuum will provide 4 staff members covering: UI/UX design, development and testing. Contributing to the delivery of all milestones. £44k in kind contribution. Tactuum will build a Minimal Viable Product (MVP) platform supporting the collections of data via a 'connected' asthma app' and devices. |
| Impact | No outputs to date as the project is still active. |
| Start Year | 2019 |
| Description | CIC Round 7 Josh Jones |
| Organisation | Fixed phage limited |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Josh Jones ability and motivation to see phage therapy benefitting patients gas enabled him to successfully lead this project and build a team with the necessary expertise to achieve project aims. |
| Collaborator Contribution | Dr Clark from Fixed Phage brings extensive experience in commercial bioscience, having acted as a senior scientist in several companies. He provides input and mentoring on commercial and non commercial aspects of this project. |
| Impact | No outputs to date, project is still live. |
| Start Year | 2019 |
| Description | CIC Round 7 Josh Jones |
| Organisation | Queen Astrid Military Hospital |
| Country | Belgium |
| Sector | Hospitals |
| PI Contribution | Josh Jones is the project lead and brought Astrid Military Hospital on board due to the extensive work with phage therapy over the last decade. The project will use phage supplied by the Belgian Military. |
| Collaborator Contribution | Phage therapy in Western Europe has been led by a team at the Queen Astrid Military Hospital in Brussels, where they have used PT for 8-9 years, and dispatched therapeutic phage across Europe. |
| Impact | No outputs to date as project is still live. |
| Start Year | 2019 |
| Description | CIC Round 7 Robert Gray |
| Organisation | DyNAbind GbmH |
| Country | Germany |
| Sector | Private |
| PI Contribution | The project lead, Dr Gray, brought DyNAbind on board due to their extensive experience in DEL and in order to achieve the project objectives. |
| Collaborator Contribution | DyNAbind has an extensive collective experience in the use of DNA-Encoded Chemical Library (DEL) technologies for pharmaceutical applications. The project will employ DyNAbind's DEL technologies to discover novel binders for the protein complex S100A8/A9. |
| Impact | No outputs to date as the project is due to start in March 2020. |
| Start Year | 2020 |
| Description | Centre for Process Innovation |
| Organisation | Centre for Process Innovation (CPI) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Provided the research for the phage therapy |
| Collaborator Contribution | Expertise into manufacturing solutions |
| Impact | Not results directly from this partnership yet |
| Start Year | 2022 |
| Description | CiC Round 7 Milly Lo |
| Organisation | Brainsview Inc |
| Country | Canada |
| Sector | Private |
| PI Contribution | During the MRC Proximity to Discovery Grant (2018) between Dr Lo and BrainsView, mentorship was provided in commercialisation of clinical research. This led to the collaboration with Dr Lo's Confidence in Concept project. |
| Collaborator Contribution | BrainsView founder, Dr Vera Nenadovic, is providing mentoring (2 hours per week) and background IP of BrainsView software for the duration of the project. Dr Nenadovic and BrainsView have developed a Minimally Viable Product (MVP) brain monitoring device targeting brain injury. The MVP is the predicate device for the seizure detection and monitoring system, which is the goal of this project. In kind support includes mentoring in system development and market research. Financial support include software development costs. |
| Impact | No outputs to date as project is still live. |
| Start Year | 2019 |
| Description | Wu/Hadoke |
| Organisation | University of Strathclyde |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research project - vascular biology expertise |
| Collaborator Contribution | Expertise in bioprinting and electrospinning - microfabrication |
| Impact | The cross-disciplinary collaboration between vascular biology (JW) and microfabrication (WS) helped to address a series of challenges in biomechanics of TEBV and led to awards of a number of research grants. |
| Start Year | 2020 |
| Title | A window in the brain |
| Description | We are the first to successfully and accurately detect seizures using brain connectivity calculation on as few as 4-channels EEG, a configuration that may be readily applied by the bedside PICU clinical team without expert input. This was done by adapting the BrainsView seizure detection algorithm by adding an extra feature extraction method (cross-channel amplitude coherence) to its existing phase synchronisation calculation. This enhanced seizure detection performance. |
| Type | Diagnostic Tool - Non-Imaging |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2021 |
| Development Status | Actively seeking support |
| Impact | Process has made it easier to detect seizures. |
| Title | Connected asthma |
| Description | A functioning prototype connected A4A+ system including connections between four existing smart devices (Findair smart inhaler, Polar fitness watch, Smart Asthma and MIR smart peak flow meters) and core self-management features (report sharing to practice, asthma action plan, customised asthma logs, contact links to Asthma UK resources, and environmental information such as air quality, pollen count and temperature). |
| Type | Management of Diseases and Conditions |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2020 |
| Development Status | Actively seeking support |
| Impact | Prototype under development |
| Title | Phage treatment |
| Description | • 9 diabetic foot infection patients have been screened for bacterial infections susceptible to the Staphylococcus aureus phage. • 7 patients have been treated (21 daily applications) with the phage. Phage therapy was an adjuvant therapy to standard antibiotic treatment • 3 amputations prevented and 2 sources of sepsis cleared, bacterial infections in the remaining two patients less susceptible to S. aureus phage therapy. • Circulating CRP, a marker of inflammation, was significantly reduced over the period of treatment |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2020 |
| Development Status | Under active development/distribution |
| Impact | • 3 amputations prevented and 2 sources of sepsis cleared, bacterial infections in the remaining two patients less susceptible to S. aureus phage therapy. • Circulating CRP, a marker of inflammation, was significantly reduced over the period of treatment |
| Description | 2021 ICEE Workshop on "Safeguarding Public Health During Infectious Disease Pandemics Using Medical Robotics, Wearable Technology, and AI" |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The focus of this workshop is on ways medical robotic systems, wearables, and AI technologies could augment, assist and support the healthcare system to safeguard public health and protect frontline healthcare workers during health crises such as the novel coronavirus pandemic. Of interests are Methods and devices to facilitate the prevention, containment, and mitigation of infectious diseases, Novel means of telehealth/telemedicine for creating physical distancing between clinicians and patients, Technologies for independent living of high-risk populations, Social robotics for supporting mental health, Wearables for monitoring COVID symptoms. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://sites.google.com/ualberta.ca/2021-icee-workshop |
| Description | Article for national newspaper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Newspaper article 'How an army of 'friendly' viruses are leading the NHS's war on superbugs. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dailymail.co.uk/health/article-11152847/How-army-friendly-viruses-leading-NHSs-war-super... |
| Description | Holiday Focus - Into University |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | This is an outreach workshop to introduce Biomedical Engineering to school pupils (aged between 7 and 12 years old). Dr Abdullateef shared her research on non-invasive seizure detection using electroencephalograms. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Holistic Integration of Design, Sensing and Intelligence in Dexterous Medical Robotic Systems |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | We organised a workshop titled "Holistic Integration of Design, Sensing and Intelligence in Dexterous Medical Robotic Systems" in 2021 international conference on Robotics and Automation. We presented some of the results of this research that were not patentable in the workshop. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://sites.google.com/view/icra2021workshop |
| Description | Launch of Intensive-Share PPI Group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Interactive workshops for families with lived experience of paediatric critical care to share current research and discuss opportunities for patient and public involvement in paediatric critical care research. 4 families (7 adults and 12 children and young people) attended. 7 families have enrolled in the Intensive Share PPI Group. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Meeting with Scottish Government - Pinnock |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Meeting with Scottish Government to advocate the need for digital asthma care with the A4Ai app presented as an exemplar digital technology. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Newspaper article |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Newspaper article on 'spread of antibiotic resistance revives interest in bacteria killing viruses' Financial Times |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ft.com/content/c6df6bc4-f87e-4adb-bc92-97985f031550 |
| Description | Newton Fund Research Links Workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Advanced Imaging Techniques for Pulmonary Disease in partnership with University of Edinburgh, Edinburgh, Scotland, UK Tiangong University, Tianjin, China |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://blogs.ed.ac.uk/nfrlw/ |
| Description | Patient and Public Involvement Group created |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Dr Lo's research group have successfully established the first patient and public involvement group for paediatric critical care in Scotland called Intensive-Share (October 2022). The Intensive-Share group comprises families with lived experience of paediatric critical care and group members have engaged in PPI activities including advising on grant applications, study documentation and dissemination materials. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Researcher and Clinician Engagement |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | This single centre engagement event allowed WiB researchers and frontline clinicians to discuss the clinical need for an objective seizure detection algorithm that can be interpreted by the bedside clinicians who are not neurology specialists. The WiB researchers showcase the WiB2 seizure detection algorithm and the PICU clinicians (our future end users) confirmed it would be highly useful at the bedside and would like to see a rapid clinical translation. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Science talk to University of the Third Age |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Jones gave a 45-minute talk about phage therapy to the Science Group of the Edinburgh University of the Third Age (U3A) in June 2020. This was a general talk about phage therapy |
| Year(s) Of Engagement Activity | 2020 |