MRC Confidence in Concept 2018 - University of Hull

Lead Research Organisation: University of Hull
Department Name: UNLISTED

Abstract

MRC Confidence in Concept 2018 - University of Hull

Technical Summary

MRC Confidence in Concept 2018 - University of Hull
 
Description Contractual Research -
Amount £114,321 (GBP)
Funding ID CICA-UoH-MICREOS-01 
Organisation Micreos 
Sector Private
Country Netherlands
Start 09/2020 
End 08/2021
 
Title Optimised Ex vivo infected human wound model 
Description Optimised Ex vivo infected human wound model 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2021 
Provided To Others? Yes  
Impact this model has been adopted by others 
 
Description Development of radiobiological assays for assessment of copper-67 radiopharmaceuticals 
Organisation King's College London
Department Division of Imaging Sciences and Biomedical Engineering
Country United Kingdom 
Sector Academic/University 
PI Contribution We have produced new copper-67 containing radiopharmaceuticals in Hull, These are therapeutic/ diagnostic agents that are being developed for cancer treatment. The compounds have been invented in the Archibald research group in Hull and tested in vivo.
Collaborator Contribution In order to fully understand the value of the therapy with copper-67 the fundamentals of the cellular response to the emitted radiation need to be investigated. Dr Samantha Terry's group in the Department of Imaging Chemistry and Biology at King's College have knowledge and expertise and helped develop these assays for this project. This data is contributing to validation of the new cancer therapeutics and design of in vivo tumour therapy response experiments.
Impact No outputs as yet. A grant application has been prepared for submission in 2022.
Start Year 2021
 
Description F-star 
Organisation F-star Biotechnology Limited
Country United Kingdom 
Sector Private 
PI Contribution The PhD studentship that is being set up from the MRC CiC cluster is aligned with F-Star, who have given the University an additional grant for about £300k
Collaborator Contribution The PhD studentship that is being set up from the MRC CiC cluster is aligned with F-Star, who have given the University an additional grant for about £300k
Impact N/A
Start Year 2021
 
Description Smith and Nephew 
Organisation Smith and Nephew
Country United Kingdom 
Sector Private 
PI Contribution Development and evaluation of a new wound diagnostic device
Collaborator Contribution Contributed funding, reagents and expertise
Impact N/A
Start Year 2019
 
Description Presentation to UK pharmaceutical company 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Based on the work funded in this grant there a connection was made with a UK pharma company on collaboration and also future developments in the UK for radiopharmaceuticals. The presentation and discussion also involved US partners in the company. This increased interest in the research and potential future collaborations. It also informed the pharma company of activity in the UK in this area and led on to future meetings to develop a partnership for radiotracer production.
Year(s) Of Engagement Activity 2021
URL https://www.blueearthdiagnostics.com/
 
Description School science talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact The activity was designed to help A level science students understand interdisciplinary science in healthcare and the role of scientists in the NHS. It also showed how research translates out of university laboratories to clinical impact.
Year(s) Of Engagement Activity 2021