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University of Sheffield – Confidence in Concept 2019

Lead Research Organisation: University of Sheffield
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept (CIC) scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions to flexibly support a portfolio of early stage translational research projects. CIC is designed to accelerate the transition from discovery research to viable translational projects by supporting preliminary studies to establish proof-of-concept so that the approach will then become competitive for more substantial translational funding.

Publications

10 25 50

 
Description Regulatory Horizons Council: the regulation of neurotechnology
Geographic Reach National 
Policy Influence Type Participation in a guidance/advisory committee
URL https://www.gov.uk/government/publications/regulatory-horizons-council-the-regulation-of-neurotechno...
 
Description Research Ethics Training
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
 
Title Machine learning algorithms for stroke rehabilitation 
Description Machine learning algorithms for reducing calibration time and number of electrodes for Brain Computer Interface treatment when used for stroke rehabilitation. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2023 
Provided To Others? No  
Impact Unknown 
 
Title Secondary Electron Hyperspectral Imaging (SEHI) validation 
Description This project aims to reduce the risks and accelerate development of biomaterials for use in the pelvic floor by introducing a new surface imaging technique. We have been able to validate the sensitivity of the SEHI technique by recording its ability to respond to macrophages which become activated to a pro-inflammatory phenotype when cultured on the stretched and oxidised mesh. This has not been achieved before and is only possible because of the extreme sensitivity of the technique. 
Type Of Material Biological samples 
Year Produced 2023 
Provided To Others? No  
Impact Our impact pathway is ongoing. We have developed a collaboration with a group in Germany who have explanted human tissues and are willing to conduct collaborative research. We are preparing a submission to BBSRC to take this work further. 
 
Title In vitro model for biomaterial testing 
Description We have developed an in vitro model that could potentially help reduce animal testing of biomaterials. 
Type Of Material Computer model/algorithm 
Year Produced 2023 
Provided To Others? No  
Impact None yet. 
 
Description Industrial Collaboration - Footfall and Heartbeats 
Organisation Footfalls and Heartbeats
Country United Kingdom 
Sector Private 
PI Contribution Partnership building and collaboration to continue a CiC-funded project
Collaborator Contribution Partnership building and collaboration to continue a CiC-funded project
Impact Ongoing investigation into the reliability and design of a product. No outputs or outcomes to report at this stage.
Start Year 2021
 
Description Pint of Science 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Pint of Science is an annual worldwide science festival which brings researchers to your local pub/cafe/space to share their scientific discoveries with you - no prior knowledge required.
Year(s) Of Engagement Activity 2024
URL https://pintofscience.co.uk/
 
Description The NIHR Sheffield Biomedical Research Centre (BRC) and Clinical Research Facility (CRF) Showcase 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Industry/Business
Results and Impact The NIHR Sheffield Biomedical Research Centre (BRC) and Clinical Research Facility (CRF) is a joint showcase event, highlighting the latest in medical research and clinical trials happening across Sheffield.
Year(s) Of Engagement Activity 2024
URL https://www.sheffieldbrc.nihr.ac.uk/news-events/sheffield-brc-and-crf-showcase-event