Child Growth and development
Lead Research Organisation:
University of Cambridge
Department Name: UNLISTED
Abstract
The aim of this programme is to predict and prevent childhood obesity by identifying genetic, dietary and other factors that act during infancy. The specific objectives are to identify genetic factors and patterns of early infant diet and growth that predict childhood obesity, and to develop and test interventions to avoid excessive infant weight gain and childhood obesity. |Childhood obesity is a major public health problem. Research is important because 1) currently there are no proven interventions to prevent childhood obesity, 2) rates of obesity are rising even in young children, 3) childhood obesity has important consequences for childhood health and development, as well as adult health.|This research is being performed in a number of UK birth cohort studies, including close collaborations with the Avon Longitudinal Study of Parents and Children (ALSPAC), the Southampton Womens Study (SWS), and the Cambridge Baby Growth Study (MRC Epidemiology Unit & Department of Paediatrics, University of Cambridge). Candidate genetic factors for study in DNA samples collected in children are selected by in collaboration with the Sanger Institute and University of Cambridge Genetics of Energy & Metabolism (GEM) consortium. Prediction models for risk of childhood obesity and its complications will be based on collaborative studies between investigators from a wide range of UK and international birth cohort studies. |A randomised controlled trial will be performed by recruiting mothers during pregnancy to test whether education to avoid excess infant nutrient intake will prevent rapid infant weight gain and childhood obesity risk. Future targeted interventions will be developed for testing in infants and young children identified to have high risk of childhood obesity.
Technical Summary
Childhood obesity has important consequences for morbidity and mortality in childhood and in later life. However, there is yet little evidence of effective strategies to prevent childhood obesity. The rising prevalence of obesity even in young pre-school children indicates that efforts to predict and prevent childhood obesity need to start very early in life. The aim of this programme is to promote the prediction and prevention of childhood obesity by identifying genetic, dietary and other factors that act during fetal and infant life.|My specific research objectives are 1) to identify common genetic variants associated with rapid infant weight gain and childhood obesity; 2) to develop prediction models for childhood obesity and its co-morbidities based on genetic variants, parental obesity, birth weight, infant weight gain, and infant diet, 3) together with the Units Prevention Programme (PI Simon Griffin) to develop and test interventions to avoid excessive infant weight gain and childhood obesity. These objectives are being tested through existing close collaborations with the Avon Longitudinal Study of Parents and Children (ALSPAC), the Southampton Womens Study (SWS), and the Cambridge Baby Growth Study (MRC Epidemiology Unit & Department of Paediatrics, University of Cambridge), and other population-based birth cohort studies. |Genetic variants are selected based on the results of genome-wide association studies for adult obesity, and timing of puberty, through our involvement in large international consortia. Many of these genetic variants appear to be very relevant to the risk of childhood obesity by influencing rates of weight gain even from the first months of life. Our studies aim to further characterise the infant growth, feeding and behavioural phenotypes that are associated with these genetic markers of adult obesity. |Prediction models for childhood obesity risk are based on meta-analysis of growth data from a wide range of birth cohort studies. Further refinement of these models will be explored by testing the addition of those early life phenotypes identified by our genetic studies, and through identification of biochemical biomarkers of infant growth and body composition. |The aetiological role of excess nutrient intake on rapid infant weight gain and childhood obesity risk will be tested by randomised controlled trial of parental education, support and behaviour change, which if successful will lead to wider pragmatic trials to test its application to public health.|In addition to my specific focus on the infant determinants of childhood obesity, I closely support the research in other programmes of the Epidemiology Unit to understand the role of childhood physical activity in the aetiology and prevention of childhood obesity. |These research objectives are also closely supported by clinical activities in setting up a secondary referral service for childhood obesity (through the Paediatric Endocrinology & Diabetes Service, Addenbrookes Hospital NHS Trust), and support for local community initiatives in school-based screening and treatment of childhood obesity.
People |
ORCID iD |
Ken Ong (Principal Investigator) |
Publications
Den Hoed M
(2013)
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
in Nature genetics
Denford S
(2018)
Improving public health evaluation: a qualitative investigation of practitioners' needs.
in BMC public health
DIAbetes Genetics Replication And Meta-Analysis (DIAGRAM) Consortium
(2014)
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
in Nature genetics
Do R
(2013)
Common variants associated with plasma triglycerides and risk for coronary artery disease.
in Nature genetics
Dumanski JP
(2021)
Immune cells lacking Y chromosome show dysregulation of autosomal gene expression.
in Cellular and molecular life sciences : CMLS
Dunger D
(2020)
Insulin Resistance - Childhood Precursors of Adult Disease
Ehret GB
(2016)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
in Nature genetics
Eleftheriou A
(2023)
Leptin and IGF-1 in Infancy Are Associated With Variants in DHCR7 and CYP2R1 That Relate With Type 1 Diabetes and 25OHD.
in The Journal of clinical endocrinology and metabolism
Elks CE
(2014)
Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis.
in JAMA pediatrics
Elks CE
(2013)
Age at menarche and type 2 diabetes risk: the EPIC-InterAct study.
in Diabetes care
Eriksson AL
(2018)
Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.
in The Journal of clinical endocrinology and metabolism
Evangelou E
(2018)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
in Nature Genetics
Fernández-Rhodes L
(2013)
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.
in American journal of epidemiology
Related Projects
Project Reference | Relationship | Related To | Start | End | Award Value |
---|---|---|---|---|---|
MC_UU_12015/1 | 30/04/2013 | 30/03/2020 | £5,553,000 | ||
MC_UU_12015/2 | Transfer | MC_UU_12015/1 | 30/04/2013 | 30/03/2020 | £3,231,000 |
MC_UU_12015/3 | Transfer | MC_UU_12015/2 | 30/04/2013 | 30/03/2020 | £2,902,000 |
MC_UU_12015/4 | Transfer | MC_UU_12015/3 | 30/04/2013 | 30/03/2020 | £3,014,000 |
MC_UU_12015/5 | Transfer | MC_UU_12015/4 | 30/04/2013 | 30/03/2020 | £4,496,000 |
MC_UU_12015/6 | Transfer | MC_UU_12015/5 | 30/04/2013 | 30/03/2020 | £3,507,000 |
MC_UU_12015/7 | Transfer | MC_UU_12015/6 | 30/04/2013 | 30/03/2020 | £3,109,000 |
Description | DAPA Toolkit citation |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | http://www.bbsrc.ac.uk/documents/1503-crosscouncil-fnh-booklet/ |
Description | Finding a Path to Safety in Food Allergy: Assessment of the Global Burden, Causes, Prevention, Management, and Public Policy. Cited by National Academies Press on 30 Nov 2016 |
Geographic Reach | North America |
Policy Influence Type | Citation in systematic reviews |
URL | https://www.nap.edu/catalog/23658/finding-a-path-to-safety-in-food-allergy-assessment-of |
Description | Society for Endocrinology's Clinical Committee |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
URL | http://www.endocrinology.org/about/committee/clinical.html |
Description | The Interplay Between Environmental Chemical Exposures and Obesity: Proceedings of a Workshop Cited by National Academies Press on 26 Jul 2016 |
Geographic Reach | North America |
Policy Influence Type | Citation in systematic reviews |
URL | https://www.nap.edu/catalog/21880/the-interplay-between-environmental-chemical-exposures-and-obesity... |
Description | World Cancer Research Fund International Continuous Update Project Workstream on Lifecourse Exposures |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Membership of a guideline committee |
URL | https://www.wcrf.org/int/continuous-update-project |
Description | World Cancer Research Fund International Continuous Update Project Workstream on Lifecourse Exposures - Scientific Advisory Board Member (KO) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Participation in a guidance/advisory committee |
Description | Written evidence to House of Commons Health and Social Care Committee Childhood Obesity Inquiry (RL) |
Geographic Reach | National |
Policy Influence Type | Contribution to a national consultation/review |
URL | https://www.cedar.iph.cam.ac.uk/resources/evidence-submissions/#HOCTC18 |
Description | (EUCAN-Connect) - A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health |
Amount | € 6,717,953 (EUR) |
Funding ID | 824989 |
Organisation | European Commission |
Sector | Public |
Country | European Union (EU) |
Start | 01/2019 |
End | 12/2023 |
Description | Capital Award |
Amount | £157,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2014 |
End | 03/2015 |
Description | Complex intervention to optimise adolescent BMI pre-conception to address the double burden of malnutrition: A RCT in rural and urban South Africa |
Amount | £2,957,399 (GBP) |
Funding ID | MR/V005790/2 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2021 |
End | 03/2026 |
Description | Development of a digital intervention to promote healthy growth during the first 2 years of life |
Amount | £151,440 (GBP) |
Funding ID | MR/T002700/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2021 |
End | 11/2023 |
Description | Early Life Aetiology and Mechanisms of Diabetes and Related Metabolic Disorders |
Amount | £4,022,000 (GBP) |
Funding ID | MC_UU_00006/2 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2025 |
Description | Global Initiative on gene-environment interaction on diabetes/obesity risk (Interconnect) |
Amount | € 1,998,313 (EUR) |
Funding ID | 602068 |
Organisation | European Commission |
Department | Seventh Framework Programme (FP7) |
Sector | Public |
Country | European Union (EU) |
Start | 09/2013 |
End | 09/2017 |
Description | Identification of age-related and age-independent changes to meiotic chromosome structure and their association with aneuploidy in human oocytes |
Amount | £497,308 (GBP) |
Funding ID | MR/M000664/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 12/2014 |
End | 08/2018 |
Description | The Wellcome Trust (JP) |
Amount | £52,133 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2013 |
End | 02/2015 |
Description | UU Supplementary Strategic Partnership (Cambridge Initiative) |
Amount | £728,295 (GBP) |
Funding ID | MR/L00002/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2013 |
End | 03/2018 |
Title | Multivariable Mendelian Randomization with Summarized Genetic Data |
Description | This is a statistical tool which provides a rapid and accessible analytic strategy that can be undertaken using publicly available data to better understand causal mechanisms |
Type Of Material | Model of mechanisms or symptoms - human |
Year Produced | 2017 |
Provided To Others? | Yes |
Impact | Wide uptake and use by the academic community. To date (March 2020) 1700 full text views 49 citations on Google Scholar |
URL | https://www.genetics.org/content/207/2/481.long |
Title | Data for "The Influence of Maternal Pregnancy Glucose Concentrations on Associations between a Fetal Imprinted Gene Allele Score and Offspring Size at Birth" |
Description | Data set to accompany the study entitled "The Influence of Maternal Pregnancy Glucose Concentrations on Associations between a Fetal Imprinted Gene Allele Score and Offspring Size at Birth" by Petry et al. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Title | EPIC-Norfolk Epigenome-Wide Association Study of Incident Type 2 Diabetes |
Description | |
Type Of Material | Database/Collection of data |
Year Produced | 2019 |
Provided To Others? | Yes |
URL | https://www.repository.cam.ac.uk/handle/1810/299058 |
Title | Elucidating the genetic architecture underlying IGF1 levels and its impact on genomic instability and cancer risk |
Description | Extended data for the article "Elucidating the genetic architecture underlying IGF1 levels and its impact on genomic instability and cancer risk". The tables in the Extended data will give more information on the discovery of genome-wide significant independent signals associated with levels of IGF1, replication study, pathway analysis, as well as the results for Mendelian Randomization analysis on IGF1 and its causal inference on mosaic loss of chromosome Y in leucocytes and cancer. |
Type Of Material | Database/Collection of data |
Year Produced | 2020 |
Provided To Others? | Yes |
URL | https://figshare.com/articles/dataset/Elucidating_the_genetic_architecture_underlying_IGF1_levels_an... |
Title | GWAS summary statistics for risk-taking |
Description | Risk-taking propensity is a trait of significant public health relevance but few specific genetic factors are known. Here we perform a genome-wide association study of self-reported risk-taking propensity amongst 436,236 white European UK Biobank study participants. We identify genome wide associations at 26 loci (P<5 x10-8), 24 of which are novel, implicating genes enriched in the GABA and GABA receptor pathways. Modelling the relationship between risk-taking propensity and BMI using Mendelian randomisation shows a positive association (0.25 approximate SDs of BMI (SE: 0.06); P =6.7 x10-5). The impact of individual SNPs is heterogeneous, indicating a complex relationship arising from multiple shared pathways. We identify positive genetic correlations between risk-taking and WHR, childhood obesity, ever-smoking, ADHD, bipolar disorder, and schizophrenia, alongside a negative correlation with women's age at first birth. These findings highlight that behavioural pathways involved in risk-taking propensity may play a role in obesity, smoking, and psychiatric disorders |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Title | Male puberty MTAG GWAS analysis |
Description | |
Type Of Material | Database/Collection of data |
Year Produced | 2020 |
Provided To Others? | Yes |
URL | https://www.repository.cam.ac.uk/handle/1810/301387 |
Title | PCOS summary statistics |
Description | This file contains data relating to the analysis discussed in "Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria." The data presented in this file is for the analysis of any diagnostic criteria, excluding the self-report based data from 23andMe. The file has the followin headers: MarkerName Effect_allele Other_allele EAF Effect [frd23@b08 PCOS]$ more PCOS_summary_data_19092018_README.txt This file contains data relating to the analysis discussed in "Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Su ggests Shared Genetic Architecture for Different Diagnosis Criteria." The data presented in this file is for the analysis of any diagnostic criteria, excluding the self-report based data from 23andMe. The file has the followin headers: MarkerName Effect_allele Other_allele EAF Effect StdErr Pvalue TotalSampleSize The data reported in this sheet has been truncated to 2 significant figures. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Title | ReproGen GWAS data |
Description | Genomewide variant association parameters for reproductive ageing traits |
Type Of Material | Database/Collection of data |
Year Produced | 2014 |
Provided To Others? | Yes |
Impact | Publicly available data which has contributed to other scientific publications by collaborators and other external investigators |
URL | http://www.reprogen.org/data_download.html |
Title | Research data supporting: Genome-wide association study for risk taking propensity indicates shared pathways with body mass index |
Description | Here, we provide the summary statistics for our GWAS of self-reported risk-taking propensity amongst 436,236 white European participants of the UK Biobank (UKB) study, measured by the question: "Would you describe yourself as someone who takes risks?". GWAS testing for associations between SNPs and self-reported risk-taking was performed using a linear mixed model (LMM) implemented in BOLT-LMM. Sex, age and genotyping array were included as covariates. SNPs were filtered based on info >0.5 and minor allele frequency >1%. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Title | Risk-taking summary statistics UK Biobank |
Description | Here, we provide the summary statistics for our GWAS of self-reported risk-taking propensity amongst 436,236 white European participants of the UK Biobank (UKB) study, measured by the question: "Would you describe yourself as someone who takes risks?". GWAS testing for associations between SNPs and self-reported risk-taking was performed using a linear mixed model (LMM) implemented in BOLT-LMM. Sex, age and genotyping array were included as covariates. SNPs were filtered based on info >0.5 and minor allele frequency >1%. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Title | Summary statistics for PCOS |
Description | This file contains data relating to the analysis discussed in "Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria." This contains two files. The first, PCOS_summary_data_19092018.tar.gz, is as follows: PCOS_summary_data_19092018.txt The data presented in this file is for the analysis of any diagnostic criteria, excluding the self-report based data from 23andMe. The file has the following headers: MarkerName; Effect_allele; Other_allele; EAF; Effect. The data presented in this file is for the analysis of any diagnostic criteria, excluding the self-report based data from 23andMe. The data reported in this sheet has been truncated to 2 significant figures. This information is also set out in the read-me file - PCOS_summary_data_19092018_README.txt The second file PCOS_top_10000_SNPS.txt, is as follows: This file contains data from the top 10000 SNPs (based on P-values) from the combined meta-analysis. This data was derived from the studies contribution to the first of these files, and data from 23andMe. The headers are: MarkerName; Allele1; Allele2; Freq1; Effect; StdErr; Pvalue; HetPVal; TotalSampleSize; EffSampleSize; chr; pos. In this file Allele 1 is the effect allele. |
Type Of Material | Database/Collection of data |
Year Produced | 2019 |
Provided To Others? | Yes |
Title | Summary statistics relating to "Elucidating the genetic basis of social interaction and isolation" |
Description | Summary statistics relating to GWAS analysis of loneliness, and attendance at particular social activities, as well as MTAG results relating to a combined analysis of loneliness and social isolation. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Description | Reprogen Consortium |
Organisation | Boston University |
Department | School of Medicine |
Country | United States |
Sector | Academic/University |
PI Contribution | Performance of genome-wide association studies and meta analysis. Expertise in genetic epidemiology and endocrinology |
Collaborator Contribution | This is the leading international consortium for the study of the genetic basis of reproductive ageing in women |
Impact | Scientific papers |
Start Year | 2009 |
Description | 23andMe Press Release: puberty |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | "23andMe Press Release ""First-of-its-kind study of puberty timing in men: New study reveals strong genetic correlation between male and female puberty timing"" on Nature communications paper by Felix Day et al. ""Shared genetic aetiology of puberty timing between sexes and with health-"" 10 articles in online news media, including Times of India, Gizmodo, Medical News Today and MedicalXpress . FD interviewed by Cambridge TV and the Naked Scientists Radio. http://timesofindia.indiatimes.com/life-style/health-fitness/health-news/Male-puberty-genetically-similar-to-female-timing/articleshow/49736093.cms" |
Year(s) Of Engagement Activity | 2015 |
URL | http://timesofindia.indiatimes.com/life-style/health-fitness/health-news/Male-puberty-genetically-si... |
Description | 23andMe press release: polycystic ovary syndrome |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press Release by 23andMe Shining a light on polycystic ovary syndrome: New genetic study reveals underlying mechanisms and potential interventions on Nature Communications Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Reported by the Jersey tribune and 12 specialist tech and medical online news outlets including MedicalXpress |
Year(s) Of Engagement Activity | 2015 |
URL | http://medicalxpress.com/news/2015-09-greater-polycystic-ovary-syndrome.htm |
Description | 23andMe press release: polycystic ovary syndrome |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press Release by 23andMe Shining a light on polycystic ovary syndrome: New genetic study reveals underlying mechanisms and potential interventions on Nature Communications Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Reported by the Jersey tribune and 12 specialist tech and medical online news outlets including MedicalXpress |
Year(s) Of Engagement Activity | 2015 |
URL | http://medicalxpress.com/news/2015-09-greater-polycystic-ovary-syndrome.htm |
Description | Age at menarche - T2DM risk (KO, CE) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | American Diabetes Association Press release on "Age at menarche and type 2 diabetes risk: the EPIC-InterAct study." Diabetes Care, PMID: 24159179 Limited coverage in international news media. |
Year(s) Of Engagement Activity | 2013 |
Description | American Society of Human Genetics Annual Meeting 2018 (BH) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | PhD student Benjamin Hollis presented a poster: "2633F A genetic atlas for reproductive health and disease in UK Biobank. B. Hollis, A.S. Busch, F.R. Day, K.K. Ong, J.R.B Perry. MRC Epidemiology Unit, University of Cambridge , Cambridge, United Kingdom. " |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.ashg.org/meetings/documents/2018-poster-abstracts.pdf |
Description | American Society of Human Genetics Annual Meeting 2018 (FD) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Dr Felix Day gave a very well received poster presentation at the American Society of Human Genetics conference held in San Diego, USA on 19th October 2018. "A multi-trait GWAS (MTAG) for puberty timing in men. F.R. Day, B. Hollis, P. Timmers, P. Joshi, D. Thompson, A.S. Busch, K.K. Ong, J.R.B. Perry, 23andMe" |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.ashg.org/meetings/documents/2018-poster-abstracts.pdf |
Description | Baby Milk BBC Radio Cambridgeshire interview (RL) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Media (as a channel to the public) |
Results and Impact | BBC Radio Cambridgeshire interviewed RL, AMW and study participant about the Baby Milk study. Interview broadcast by BBC Radio Cambridgeshire Breakfast Show on 18/08/14 |
Year(s) Of Engagement Activity | 2014 |
URL | http://www.bbc.co.uk/programmes/p0247b0r |
Description | Baby Milk Study 500th baby (RL, KO) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Media (as a channel to the public) |
Results and Impact | MRC Epidemiology Unit press release "500th baby joins pioneering infant nutrition study at the University of Cambridge" issued to regional media outlets : Cambridge News, Peterborough Telegraph, BBC Radio Cambridgeshire, Heart FM. On 21 /07/14 published on Unit website and tweeted to @MumsnetCambs, @LocalSCambridge, @CambridgeNews @CambridgeCC @camscience @BBCCambs @enableeast @peterboroughtel@richardkendall @julianhuppert @SJacksonMP @JDjanogly @SteveBarclayMP. Article in Cambridge News. News Editor BBC Cambridgeshire / BBC Look East requested interviews with parents/lead researchers for radio report after a tweet was forwarded to her. ITV News Anglia interiewed lead researcher and mum on 05/08/2014 Unit tweets retweeted by 8 accounts, including 2 of those targeted (@MumsnetCambs and @camscience). |
Year(s) Of Engagement Activity | 2014 |
URL | http://www.mrc-epid.cam.ac.uk/500th-baby-joins-pioneering-infant-nutrition-study-at-the-university-o... |
Description | Big Biology Day, Hills Road Sixth Form College, Cambridge (FD) |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | Big Biology Day. Unit members participated in two IMS stands at the Big Biology Day event held at Hills Road 6th Form College. The first stand was a "Science festival" type stand with hands-on activities for families, for which the Unit provided the "Sugar Cube Challenge" and "Sweet Enough Challenge" activities which we had developed earlier. Unit members also contributed to a "faces of the IMS" booklet which gave examples of different career paths at the IMS, and which were handed out at a stand in the careers fair part of the event. The hands-on stand had over 250 visitors, and hundreds of CEDAR and MRC Epidemiology leaflets were handed out. (as well as most of our MRC Rulers and pens!) and queues to take part in activities for most of the day. There was a higher proportion of teens compared to the Cambridge Science Festival in March. There were fewer visitors to the stand at the careers fair, though still over 50 in the course of the day. Subsequently received request for work experience from 6th form student who visited careers stand. |
Year(s) Of Engagement Activity | 2017 |
Description | Big Wednesday event |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | Yes |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | Unit took part in Cambridge City Council Chypps "Big Wednesday" event which had an urban festival theme. Stand focused on physical activity and included activities for chlidren to join in. 50-60 children participated in activities at the stand, and about 50 parents talked to volunteers about the Unit and its activities, and the importance of a healthy diet and physical activity. To be determined. |
Year(s) Of Engagement Activity | 2014 |
URL | https://www.cambridge.gov.uk/chypps-overview |
Description | Blog - Circulating glycine is genetically associated with lower risk of coronary heart disease (FD) |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | A paper Dr Felix Day co-authored was reported on the MRC Epidemiology Unit blog, the audience of which is academic colleagues / peers / researchers. It received 78 unique page views for Unit blog article 5-6 March 2019. Tweeted by 20 tweeters, Altmetric score of 16 on 05/12/2019. |
Year(s) Of Engagement Activity | 2019 |
URL | http://www.mrc-epid.cam.ac.uk/blog/circulating-glycine-coronary-heart-disease/ |
Description | Boots WebMD interview - how genes affect children (FD) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Interview for Boots WebMD article on how genes affect children. Article "What will my baby look like" published on 26 September 2017 |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.webmd.boots.com/pregnancy/features/what-will-my-baby-look-like |
Description | CNN interview - role of genes in sexual behaviour |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | CNN International interview on the role of genes in sexual behaviour for web articles http://edition.cnn.com/2016/08/07/health/gallery/genes-sexual-behavior/index.html http://edition.cnn.com/2016/08/07/health/genes-decide-virginity-loss/ |
Year(s) Of Engagement Activity | 2016 |
URL | http://edition.cnn.com/2016/08/07/health/genes-decide-virginity-loss/ |
Description | CU Press release Press release - Menarche Genes - Nature (KO, JP) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Cambridge University Press release "Age of puberty in girls influenced by which parent their genes are inherited from" on Nature paper "Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche". Lead author JP received 14 requests for interviews from journalists. Reported in 22 articles in mainstream National and International media, including: http://www.bbc.co.uk/news/health-28417485 |
Year(s) Of Engagement Activity | 2014 |
URL | http://www.mrc-epid.cam.ac.uk/age-of-puberty-in-girls-imprinted-genes/ |
Description | Cambridge News - Walking Routes |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Raj Lakshman quoted in new Cambridge News article on new map of walking routes in Cambridge |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.cambridge-news.co.uk/New-walking-map-set-launch-Addenbrooke-8217-s/story-26523253-detail/... |
Description | Cambridge News: Baby Milk draft |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Submitted draft article on Baby Milk study for publication in health section of Cambridge News. |
Year(s) Of Engagement Activity | 2015 |
Description | Cambridge Science Festival |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | Yes |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | Interactive stand at the Cambridge Science Festival. Typical attendance around 300 visitors, including children and adults. Inquiries from school teachers and members of the public for further information. Excellent feedback from visitors and consistently good attendance at the stand. |
Year(s) Of Engagement Activity | 2007,2008,2009,2010,2011,2012,2013,2014,2015 |
URL | http://www.cam.ac.uk/science-festival |
Description | Cambridge Science Festival - A healthier you in a digital future (FD) |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Stand "A healthier you in a digital future"at Cambridge Science festival hands-on event at Cambridge Guildhall, including adults only session on the evening of Saturday 18th. Posters on factors influencing food choice, wearable fitness trackers and their research counterparts, and use of antibodies in our research. Activities included the "Things can only get Bitter" bitter taste test, the Race to 20,000 steps challenge using fitness monitors, and making antibodies out of play-doh and magnets. More than 500 visitors, including more than 300 children, attended our stand over the two days, and participated in activities and talked with Unit staff. The response was very positive. We also gave away over 150 copies of a MRC Cambridge colouring book and flyers for the MRC Festival in June. |
Year(s) Of Engagement Activity | 2017 |
URL | https://www.sciencefestival.cam.ac.uk/events/healthier-you-high-tech-future |
Description | Cambridge Science Festival Talk - Genes and Behaviours (JP) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Public talk for Cambridge Science Festival 2017 "Do our genes influence our behaviours?". Held in Mill Lane Lecture rooms. Talk was highlighted by the Science Festival, and tickets sold out weeks before the event. More than 200 people attended the talk, and there was a lively Q&A session after it concluded. After the talk and Q&A had officially finished many attendees queued to speak one-to-one. |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.sciencefestival.cam.ac.uk/system/files/cambridge_science_festival_2017_0.pdf |
Description | Cambridge TV - FD |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Felix Day interviewed on Cambridge TV on Health & Puberty |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.cambridge-tv.co.uk/felix-day/ |
Description | Cambridge University press release - Menarche and cancer risk |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Cambridge University press release for Nature Genetics paper "Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk" by Felix Dat et al. https://doi.org/10.1038/ng.3841 Versions of the press release were posted on the research news web pages of the University of Cambridge, MRC Epidemiology Unit, and 23and Me. John Perry interviewed by Evening Standard, Wiener Zeitung, De Kennis van Nu, Telegraph & Daily Mail, and Felix Day was interviewed live for BBC Radio 5 Live on 25 April and That's Cambridge TV evening news on 27 April. Covered in print and online in Daily Mail, Evening standard, Telegraph, Wiener Zeitung, Times, GenomeWeb, Science Daily and MedicalXpress, plus about 70 more specialist, local and regional online news outlets. Covered in University of Cambridge Clinical School Newsletter on19 May 2017. Evidence of impact: http://www.dailymail.co.uk/health/article-4440482/An-early-puberty-raises-cancer-risk.html, https://www.standard.co.uk/news/health/reaching-puberty-early-raises-the-risk-of-cancer-in-later-life-say-scientists-a3522456.html, http://www.telegraph.co.uk/science/2017/04/24/early-puberty-increases-cancer-risk-research-proves/ |
Year(s) Of Engagement Activity | 2017 |
URL | https://www.eurekalert.org/pub_releases/2017-04/uoc-sih042117.php |
Description | Cancer Research UK Grand Challenge announcement (JP) |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | News article on Unit website http://www.mrc-epid.cam.ac.uk/blog/cancer-research-uk-grand-challenge/ on shortlisting of proposed research project on role of inflammation in cancer for Cancer Research UK Grand Challenge. Also featured on CRUK website http://www.cancerresearchuk.org/funding-for-researchers/how-we-deliver-research/grand-challenge-award/shortlistedteamli and on the Crick https://crick.ac.uk/news/news-archive/2018/02/08/crick-group-leader-in-team-shortlisted-for-cruk-grand-challenge-award/ and Gurdon Institute https://www.gurdon.cam.ac.uk/news/GrandChallengeAnnounce websites. Shared on Unit Twitter, Facebook and LinkedIn. |
Year(s) Of Engagement Activity | 2018 |
URL | http://www.mrc-epid.cam.ac.uk/blog/cancer-research-uk-grand-challenge/ |
Description | Childhood obesity - UK trends and body composition measurements |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Professional Practitioners |
Results and Impact | This was a seminar for pediatric health professionals/pediatricians in Addenbrookes Hospital presentation: Childhood obesity - UK trends and body composition measurements |
Year(s) Of Engagement Activity | 2016 |
Description | Comment: Hussen et al |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Provided comment to Science Media centre on new paper by Hussen et al. "Maternal overweight and obesity are associated with increased risk of type 1 diabetes in offspring of parents without diabetes regardless of ethnicity" Diabetologia. |
Year(s) Of Engagement Activity | 2015 |
Description | Confidence Interval Podcast (FD) |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Oliver Francis talks to Dr Felix Day in the Growth and Development programme at the MRC Epidemiology Unit about genetics, puberty and unusual career trajectories. (Since recording, Felix has been promoted from Career Development Fellow to Senior Research Associate.) |
Year(s) Of Engagement Activity | 2018 |
URL | https://sms.cam.ac.uk/media/2857875 |
Description | EDMaRC Workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | EDMaRC Workshop: Regulation of the Pituitary-Gonadal Axis in Childhood, Adolescence and Adults; Minipuberty and Puberty. Invited speaker. |
Year(s) Of Engagement Activity | 2016 |
Description | EPIC Norfolk Volunteer Panel presentation |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Study participants or study members |
Results and Impact | Presentation to EPIC Norfolk Volunteer Panel "Measurement of Obesity, and what we can learn from it". |
Year(s) Of Engagement Activity | 2016 |
Description | Early life, body composition in relation to cardio-metabolic outcomes |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Professional Practitioners |
Results and Impact | invited speaker to the Physiology meetings run by the Department of Pediatric, University of Cambridge and IMS, presentation for physiology meetings: Early life, body composition in relation to cardio-metabolic outcomes |
Year(s) Of Engagement Activity | 2016 |
Description | East of England Wellbeing Show |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | MRC Epidemiology Stand and talk by Nick Wareham at East of England Well Being Show http://www.eastofenglandwell-beingshow.org.uk/ attended by approximately 1,000 members of the public. Our stand included promotional material for studies that are now recruiting, and an activity to see how exercise affects heart rate. To be determined. |
Year(s) Of Engagement Activity | 2014 |
URL | http://www.eastofenglandwell-beingshow.org.uk/ |
Description | European Center for Reproductive Endocrinology conference (JP) |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Dr John Perry was an invited speaker at the European Center for Reproductive Endocrinology conference. |
Year(s) Of Engagement Activity | 2018 |
Description | Fenland Study public meetings - Cambridge, Ely, Wisbech |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Study participants or study members |
Results and Impact | Public Meetings for Fenland Study participants in Cambridge, Ely, and Wisbech. The event consisted of a poster display & meet and greet session (30 minutes), followed by a presentation (20 minutes) and panel discussion with audience Q&A (40 minutes). The three meetings were well attended, with about 550 people in total, and there was a very high level of audience engagement, with many excellent questions and good feedback after the event. |
Year(s) Of Engagement Activity | 2016 |
Description | Genetic Obesity Susceptibility (KO, CE) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | JAMA Pediatrics Press Release "Analysis Examines Genetic Obesity Susceptibility, Association with Body Size in Kids " on paper Pubmed 25329327. KO discussed implications of the study with a HealthDay reporter. 5 reports in Online international news media, including medical news media. |
Year(s) Of Engagement Activity | 2014 |
URL | http://www.philly.com/philly/health/kidshealth/HealthDay692896_20141021_Tall__Heavy_1-Year-Olds_May_... |
Description | Guardian - Teenage obesity rates |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Quoted in article "Teenage obesity rates could be linked to body's 'energy saving mode'" in Guardian, commenting on new research from University of Exeter. https://www.theguardian.com/science/2016/sep/08/teenage-obesity-rates-could-be-linked-to-bodys-energy-saving-mode |
Year(s) Of Engagement Activity | 2016 |
URL | https://www.theguardian.com/science/2016/sep/08/teenage-obesity-rates-could-be-linked-to-bodys-energ... |
Description | Guardian - early puberty, menopause heart disease (JP) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Dr John Perry provided a quote to the Guardian for article on links between early puberty and menopause in women and later risk of heart disease https://www.theguardian.com/society/2018/jan/15/early-menarche-and-menopause-linked-to-cardiovascular-disease-risk-study |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.theguardian.com/society/2018/jan/15/early-menarche-and-menopause-linked-to-cardiovascula... |
Description | Guardian - early puberty, menopause heart disease (JP) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Provided quote to Guardian for article on links between early puberty and menopause in women and later risk of heart disease https://www.theguardian.com/society/2018/jan/15/early-menarche-and-menopause-linked-to-cardiovascular-disease-risk-study |
Year(s) Of Engagement Activity | 2017 |
URL | https://www.theguardian.com/society/2018/jan/15/early-menarche-and-menopause-linked-to-cardiovascula... |
Description | Heliyon Blog Q&A |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Provided Q&A for a profile on the Heliyon blog as part of their efforts to highlight their journal Editorial Advisors on their blog |
Year(s) Of Engagement Activity | 2015 |
URL | http://blog.heliyon.com/post/117156528406/say-hello-to-editorial-advisor-john-perry |
Description | Heliyon Press Release - Summer Children |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | "Heliyon Press Release ""Children Born in the Summer More Likely To Be Healthy Adults"" on paper ""Season of birth is associated with birth weight, pubertal timing...."" Reported by 200+ National and International press outlets, including the Times, Daily Mail, Huffington Post, and CNN. Also covered by 10+ specialist medical and science news outlets. This was one of EurekAlert's top 10 most popular press releases in 2015. " |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.dailymail.co.uk/health/article-3269337/Why-summer-baby-good-health-People-born-June-July-... |
Description | Hot topics in bioscience I wished I knew more about (FD) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Dr Felix Day took part in the "Hot topics in bioscience I wished I knew more about" talk. What is gene editing and why should I care? Can we cure Alzheimer's disease? What can I do with a stem cell? If I've got the obesity gene, does this mean I'm going to be obese? Nine crucial months: how does our health begins in the womb? Hear our expert panel answer these questions and any more that you may have about biosciences, for anyone from 15 to 115, no previous expertise required! Featuring a star team of Dr Rachael Bashford-Rogers, Dr Sybil Stacpoole, Dr Jenny Hirst, Dr Tessa Sinnige, Dr Emily Camm, and Dr Felix Day this event will be chaired by Dr Julian Huppert, Director of the Intellectual Forum at Jesus College. |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.sciencefestival.cam.ac.uk/system/files/csf_online_final_0118_0.pdf |
Description | Huffington Post LIVE |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Dr Felix Day discussed new Biobank research on puberty timing and health on Huffington Post Live |
Year(s) Of Engagement Activity | 2015 |
URL | http://live.huffingtonpost.com/r/segment/charleston-shooting-brian-williams-breast-milk-top-stories/... |
Description | IAEA - DAPA Measurement toolkit (EDLR) |
Form Of Engagement Activity | A magazine, newsletter or online publication |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Dr Emanuella De Lucia Rolfe was featured in an article on DAPA Measurement in IAEA Nutritional & Health Related Environmental Studies Newsletter following a conversation with Cornelia Loechl, Section head for Nutritional & Health-Related Environmental Studies Section, International Atomic Energy Agency. |
Year(s) Of Engagement Activity | 2018 |
Description | ITV News Anglia about Baby Milk study (RL) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Raj Lakshman and study volunteer interviewed by reporter from ITV News Anglia about Baby Milk study Report broadcast by ITV News Anglia in 6pm bulletin 06/08/14 Received positive feedback from volunteers involved in the study, and several additional requests to participate. |
Year(s) Of Engagement Activity | 2014 |
URL | http://vimeo.com/102734731 |
Description | Interview - Russian TV |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Featured in Russian TV documentary "Cold" which looked at her analysis of the genomes of indigenous Siberian populations for genetic variants accociated with cold adaptation and diet http://tvkultura.ru/video/show/brand_id/60162/episode_id/1267658/ Led to live interview with Maltese TVAM on 06/03/2016 http://www.tvm.com.mt/mt/programmes/tvam-4/ondemand/ |
Year(s) Of Engagement Activity | 2016 |
URL | http://tvkultura.ru/video/show/brand_id/60162/episode_id/1267658/ |
Description | Interview TVAM Malta |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Interview with Maltese TVAM on 06/03/2016 http://www.tvm.com.mt/mt/programmes/tvam-4/ondemand/ about her research looking at the genomes of indigenous Siberian populations to identify genetic variants associated with cold adaptation and diet |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.tvm.com.mt/mt/programmes/tvam-4/ondemand/ |
Description | Irish Endocrine Society Conference 2018 (JP) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Dr John Perry was invited to speak at the 2018 Irish Endocrine Society conference. |
Year(s) Of Engagement Activity | 2018 |
Description | Jesus College Year 10 residential (FD) |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Schools |
Results and Impact | Dr Felix Day took part in the Jesus College Year 10 residential day held on 2nd July 2018. He championed the MRC Epidemiology Unit and the University of Cambridge School of Clinical Medicine, and discussed education and career options with visiting year 10 students, as well as the benefits of being part of Jesus College. |
Year(s) Of Engagement Activity | 2018 |
Description | London International Youth Science Forum visit to School of Clinical Medicine (TSC) |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Schools |
Results and Impact | London International Youth Science Forum visit to School of Clinical Medicine. Seven 17-18 year old students from around the world visited the MRC Epidemiology Unit , where they visited the Anthropometry suite and Laboratory, and had an introductory talk about the Unit and it's work, and a talk by two PhD students from outside the UK, one of which was Tuck Seng Cheng. |
Year(s) Of Engagement Activity | 2019 |
Description | London Youth Science Forum |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | Yes |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | 10 Students visited the Unit as part of London International Youth Science Forum activities. Luca Lotta gave an ovreview of the Unit's research programmes, and an introduction to his own recent research on the discovery of biomarkers and causal mechanisms for the metabolic consequences of obesity. They were then taken on a tour of Unit facilities, which included demonstrations of body composition and physical activity assessment. They were also provided withprinted information on the Unit, it's organization and research activities. To be determined. |
Year(s) Of Engagement Activity | 2014 |
URL | http://www.liysf.org.uk/ |
Description | MRC Epidemiology Unit Research blog - Understanding the causes and consequences of mosaic Y chromosome loss |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Unit research blog post "Understanding the causes and consequences of mosaic Y chromosome loss" published for Nature paper "Genetic predisposition to mosaic Y chromosome loss in blood" https://doi.org/10.1038/s41586-019-1765-3. Shared on Unit Twitter, Facebook and Linked in channels. Article submitted to Clinical School Newsletter. Reported in the Daily Mail https://www.dailymail.co.uk/health/article-7764827/Y-chromosomes-mysteriously-DISAPPEAR-44-men-time-reach-70.html and Atlantic https://www.theatlantic.com/science/archive/2019/12/men-lose-y-chromosomes-cells-they-age/603013/, and other online news outlets including Infobae and Sputnik News. Reported in the University of Cambridge School of Clinical Medicine Newsletter on 25 November 2019. Altmetric score of 163 on 018/12/2019 https://www.altmetric.com/details/70857048 Tweeted 238 times by 222 twitter accounts. Recommended by F1000Prime https://f1000.com/prime/736936377 |
Year(s) Of Engagement Activity | 2019 |
URL | http://www.mrc-epid.cam.ac.uk/blog/causes-consequences-mosaic-y-chromosome-loss/ |
Description | MRC Press Release - LPL-enhancing drugs (JP, FD) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | MRC Press Release "New drugs could reduce risk of heart disease and diabetes when added to statins, according to genetic study simulating clinical trial" on JAMA Cardiology publication "Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes". Reported by Daily Mail (Print and online) https://www.dailymail.co.uk/health/article-6185367/Give-millions-patients-statins-new-type-drug.html, Inews https://inews.co.uk/news/health/new-drug-statins-reduce-diabetes-heart-disease/, Breitbart https://www.breitbart.com/news/study-drug-combo-could-reduce-heart-attack-risk/ and at least 6 other online news outlets and tweeted by more than forty accounts. LL did interview with MedicalResearch.com https://medicalresearch.com/diabetes/lowering-triglycerides-and-cholesterol-could-reduce-heart-disease-and-diabetes-risk/44600/ |
Year(s) Of Engagement Activity | 2018 |
URL | http://www.mrc-epid.cam.ac.uk/blog/drugs-reduce-risk-heart-disease-diabetes/ |
Description | MRC Timing of Puberty press release |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | MRC Press Release "Study finds timing of puberty has wide-ranging impacts on health in later life" on Felix Day et al. "Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study" Scientific Reports (2015). // Felix Day interviewed by BBC Health Editor for online news article, and by reporters from Times and Daily Mail. Covered by BBC online news article, and online articles in Guardian and Telegraph, plus on 3 reports in online health news outlets. FD also did live video interview with Huffington Post Live. |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.bbc.co.uk/news/health-33168864 |
Description | Menopause DNA repair |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | "Maintaining healthy DNA delays menopause"; on Nature Genetics paper "Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair." Reported by at least 100 national, international and specialist news outlets, including BBC News online, ABC News online, Mirror, Daily Mail, and GenomeWeb. |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.bbc.co.uk/news/health-34380258 |
Description | NPRI Baby Milk Trial interview (RL) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Interview with National Prevention Research Initiative regarding the Baby Milk Trial. To be determined |
Year(s) Of Engagement Activity | 2014 |
Description | Naked Scientists - Puberty Timing |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Can you remember when your voice broke? According to conventional wisdom most men can't, but women have very strong memories of their first period. This means that studies of puberty timing have struggled to investigate effects in men. However, new work from the University of Cambridge using data from 23andMe has shown that men have much more reliable memories than once thought as Dr Felix Day explained to Connie Orbach. |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.thenakedscientists.com/HTML/podcasts/show/20151113/ |
Description | Nature Press Release - genetic basis of social interaction (FD, KO, JP) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Reported by the Telegraph https://www.telegraph.co.uk/science/2018/07/03/obesity-epidemic-could-fuel-loneliness-scientists-find-genetic/, Daily Mail http://www.dailymail.co.uk/health/article-5913851/Loneliness-genes.html, Discover Magazine http://blogs.discovermagazine.com/d-brief/2018/07/03/25452/#.W0OKA4r_rcv and about twenty other online international news outlets. |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.telegraph.co.uk/science/2018/07/03/obesity-epidemic-could-fuel-loneliness-scientists-fin... |
Description | Nature or Nurture - Cambridge Science Festival |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | "Talk 'Nature Versus Nurture: What population genetics can tell us'. Lecture room with a capacity of 240 people was booked out.91% of respondents to our feedback request agreed the event was very good. 89% said it was pitched at the correct level for the audience." |
Year(s) Of Engagement Activity | 2016 |
Description | News Medical - Insights from Industry |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | John Perry did interview with April Cashin-Garbutt for News Medical article "Genetic factors in puberty timing: an interview with Dr John Perry" |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.news-medical.net/news/20160111/Genetic-factors-in-puberty-timing-an-interview-with-Dr-Joh... |
Description | Nutrition and Growth 2018 (EdLR) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Dr Emanuella de Lucia Rolfe gave a presention titled "Early Life Determinants Of Central Adiposity In Young Adulthood: The Birth To 20 Cohort" at the Nutrition and Growth 2018 conference. |
Year(s) Of Engagement Activity | 2018 |
URL | http://2018.nutrition-growth.kenes.com/Documents/NGC%202018%20Final%20Program%202%202-25-18.pdf |
Description | Press Release - JAMA - LDL lowering and Diabetes |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | JAMA Press release "Certain LDL-C-Lowering Genetic Variants Associated with Higher Risk of Type 2 Diabetes" for paper "Association between Low-Density Lipoprotein Cholesterol Lowering Genetic Variants and Risk of Type 2 Diabetes" PubMed:27701660. Unit news blog post http://www.mrc-epid.cam.ac.uk/blog/new-genetic-analysis-provides-insight-side-effects-cholesterol-lowering-drugs/. Three reports in specialist online health & science news resources. http://www.medicalnewstoday.com/articles/313272.php, https://www.genomeweb.com/genetic-research/type-2-diabetes-risk-linked-genetic-variants-associated-low-ldl-cholesterol, http://www.newswise.com/articles/certain-ldl-c-lowering-genetic-variants-associated-with-higher-risk-of-type-2-diabetes. Featured in University of Cambridge School of Clinical Medicine newsletter on 14/10/2016. |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.mrc-epid.cam.ac.uk/blog/new-genetic-analysis-provides-insight-side-effects-cholesterol-lo... |
Description | Press Release on disappearing chromosomes |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release "Unravelling the mystery of the disappearing chromosomes" issued to local and specialist media, and science correspondents at Guardian, Times and BBC. Press release also posted online on Unit Website. Press release shared by Medical News Today and Bioportfolio. Included in clinical School roundup on 13/4/2017. Tweeted 56 times by 51 tweeters. |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.mrc-epid.cam.ac.uk/blog/unravelling-mystery-disappearing-chromosomes/ |
Description | Press Release on disappearing chromosomes |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release "Unravelling the mystery of the disappearing chromosomes" issued to local and specialist media, and science correspondents at Guardian, Times and BBC. Press release also posted online on Unit Website. Press release shared by Medical News Today (https://www.medicalnewstoday.com/releases/316625.php) and Bioportfolio. Included in clinical School roundup on 13/4/2017. Tweeted 56 times by 51 tweeters. |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.mrc-epid.cam.ac.uk/blog/unravelling-mystery-disappearing-chromosomes/ |
Description | Press Release: ProAsk |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | APU and University of Nottingham press release on ProAsk online resource "Study to discover babies' risk of becoming overweight: New computer programme allows health visitors to talk to parents and intervene" // Reported on AM BBC Look East (19/05/15), and PM ITV Anglia News , and article on MedicalXpress http://medicalxpress.com/news/2015-05-baby-healthy.html. Also reported in Cambridge Evening News and on Heart FM, Capital Radio, Smooth Radio and on the Mark Forrest show 18 May (20.40) which goes out across 39 different local Radio Stations . |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.itv.com/news/anglia/update/2015-05-19/could-a-new-computer-programme-tell-us-if-babies-wi... |
Description | Press release - Baby's genes and later life |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | MRC Epidemiology Unit Press release "How baby's genes influence birth weight and health in later life" issued too local and regional news outlets for paper "Genome-wide associations for birth weight and correlations with adult disease" PubMed:27680694. This press release was adapted from one issued to national and international media by the University of Exeter and University of Oxford. Ken Ong did a recorded interview for ITV Anglia, which was broadcast during their main evening news http://www.itv.com/news/anglia/update/2016-09-28/scientists-make-baby-birthweight-breakthrough/ and was also interviewed live by BBC Radio Cambridgeshire for their Breakfast News programme www.bbc.co.uk/programmes/p047l23s. Cambridge News also covered the paper http://www.cambridge-news.co.uk/cambridge-scientists-explain-link-between-low-weight-at-birth-and-risk-of-diabetes/story-29760402-detail/story.html There were also reports in the Guardian https://www.theguardian.com/science/2016/sep/28/birth-weight-influenced-by-genes-linked-to-disease-risk-study-reveals and more than a dozen national and international specialist online outlets arising from the Oxford, Exeter and Queensland press releases. |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.itv.com/news/anglia/update/2016-09-28/scientists-make-baby-birthweight-breakthrough/ |
Description | Press release - adipose storage - University of Cambridge |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Cambridge press release "Inability to safely store fat increases risk of diabetes and heart disease" on Nature Genetics paper "Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance" PubMed:27841877. LL had phone interviews with journalists from BBC Radio 4 and BBC News online, and with Cambridge TV. Reported by BBC News online http://www.bbc.co.uk/news/health-37973303 and on the BBC Radio 4 Six O'Clock News http://www.bbc.co.uk/programmes/b082962f (segment starts at 21:58) and iPlayer/red button, and by NHS Choices http://www.nhs.uk/news/2016/11November/Pages/Fat-storage-problems-may-increase-diabetes-risk.aspx. Luca Lotta was interviewed by Cambridge TV http://www.cambridge-tv.co.uk/15-11-2016-evening-news/ (Interview starts at 4:50) and the paper was reported by Cambridge News and the Cambridge Network. Altmetric score on 123 on 16/11 reflected a substantial engagement on twitter. The paper was also covered in reports on at least 24 online news outlets, mostly medical and scientific but including some international outlets. Also featured in University of Cambridge School of Clinical Medicine newsletter on 25/11/2016 and Wolfson College newsletter. |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.bbc.co.uk/news/health-37973303 |
Description | Public Health England's Scientific Advisory Committee on Nutrition: Subgroup on Maternal and Child Nutrition |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | PHE SACN - Feeding in first year Public Health England's Scientific Advisory Committee on Nutrition: Subgroup on Maternal and Child Nutrition, chaired by Professor Ken Ong published https://www.gov.uk/government/news/sacn-publishes-feeding-in-the-first-year-of-life-report. It found that many - 75% - of infants in the UK are overfed.The report makes several recommendations to improve infant nutrition, including on support for breastfeeding and the introduction of complementary feeding. Full report at https://www.gov.uk/government/publications/feeding-in-the-first-year-of-life-sacn-report. Reported in online BBC article https://www.bbc.co.uk/news/health-44857348, Daily Mail http://www.dailymail.co.uk/health/article-5965567/Official-guidance-parents-confused-feed-babies.html, Huffington Post https://www.huffingtonpost.co.uk/entry/three-quarters-of-babies-and-toddlers-are-overeating-new-feeding-guidelines_uk_5b4eeba0e4b0de86f4881627 and Just Food https://www.just-food.com/news/three-quarters-of-uk-infants-eat-too-much-officials-say_id139676.aspx British Nutrition Foundation https://www.nutrition.org.uk/nutritioninthenews/new-reports/feedinginthefirstyear.html Goodtoknow https://www.goodtoknow.co.uk/family/public-health-england-warns-that-too-many-babies-are-overfed-423317 Brinkwire https://en.brinkwire.com/health/official-guidance-for-parents-confused-over-what-to-feed-their-babies/ |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.gov.uk/government/news/sacn-publishes-feeding-in-the-first-year-of-life-report |
Description | Radio 5 Live (FD) |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Felix Day gave an interview on the paper Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. (Day FR et al, Nat Genet 49(6):834-841 Jun 2017). |
Year(s) Of Engagement Activity | 2017 |
Description | ReproUnion 2018 (JP) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Dr John Perry was invited to speak at the "ReproUnion" annual meeting - an international network of reproductive biology investigators. |
Year(s) Of Engagement Activity | 2018 |
Description | Reproductive onset and success |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | "Press releases from Nature Genetics and the MRC Press Office on new publication PubMed:27089180. Press releases accompanied by Conversation article ""Losing your virginity: how we discovered that genes could play a part"" https://theconversation.com/losing-your-virginity-how-we-discovered-that-genes-could-play-a-part-58004 by JP & KO. JP, KO, FD gave phone interviews to journalists from The Verge, New Scientist, Boston globe, Scientific American, Wired, LiveSciance, Helsingin Sanomat, Daily Telegraph, STAT, VICE. KO recorded radio interview with ABC News (Australia). Press release featured on MRC, University of Cambridge and Unitnews blogs http://www.mrc-epid.cam.ac.uk/blog/uk-biobank-study-identifies-gene-changes-that-influence-timing-of-sexual-behaviour/. Reported online in more than 100 national and international news outlets in at least 15 countries including Guardian https://www.theguardian.com/science/2016/apr/18/genes-influence-the-age-at-which-you-lose-your-virginity-first-sex-dna, PBS news http://www.pbs.org/newshour/rundown/love-in-this-club-genome-virginity/, and Daily Mail http://www.dailymail.co.uk/sciencetech/article-3546129/Is-DNA-making-promiscuous-Genes-linked-risk-taking-influence-people-s-sexual-activity.html. Print articles in Times, Sun and Daily Mail. The Conversation article was republished by at least 3 outlets, and received more than 25,000 views, including the Independent http://www.independent.co.uk/news/science/losing-virginity-genes-study-science-cambridge-genetics-a6990891.html. KO interview with ABC News was broadcast on 19/04/16 http://www.abc.net.au/worldtoday/content/2016/s4445929.htm. Very good follow-up article on CNN 08/08/2016 edition.cnn.com/2016/08/07/health/genes-decide-virginity-loss/" |
Year(s) Of Engagement Activity | 2016 |
URL | https://theconversation.com/losing-your-virginity-how-we-discovered-that-genes-could-play-a-part-580... |
Description | Research Communication - Study identifies hundreds of genes that influence timing of puberty and alter risk of several cancers |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | The largest genomic analysis of puberty timing in men and women conducted to date has identified 389 genetic signals associated with puberty timing, four times the number that were previously known. Dr John Perry and Prof Ken Ong were interviewed for the research communication, and their comments appear throughout. |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.cam.ac.uk/research/news/study-identifies-hundreds-of-genes-that-influence-timing-of-puber... |
Description | Reuters BLISS study |
Form Of Engagement Activity | A magazine, newsletter or online publication |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Editorial on on the BLISS study was published in JAMA Pediatrics, and shared on MRC Epidemiology Unit twitter account. Reuters article quoted JAMA Pediatrice editorial, and was republished by Yahoo News, Business Insider and Eyewitness news. StuffNews, MedPageToday, OnMedica and Medscape also published articles on the editorial. 52 tweeters tweeted the article. Evidence of impact: http://www.reuters.com/article/us-health-feeding-baby-led-idUSKBN19V2DE, https://www.stuff.co.nz/life-style/parenting/baby/94565468/babies-who-eat-widely-and-feed-themselves-less-fussy-as-they-age--study, http://www.medpagetoday.com/Pediatrics/Obesity/66512, http://www.onmedica.com/newsArticle.aspx?id=ffe26677-da23-441b-b2c3-82b1355b6781 |
Year(s) Of Engagement Activity | 2017 |
URL | https://jamanetwork.com/journals/jamapediatrics/fullarticle/2634358 |
Description | SNPs and Human Diseases course |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | Invited lecturer for a post graduate training course - SNPs and Human Diseases course |
Year(s) Of Engagement Activity | 2016 |
Description | SNPs and human diseases |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | Invited speaker - SNPs and human diseases, Lecture to Postgraduate students |
Year(s) Of Engagement Activity | 2016 |
Description | Science Media Centre - sugary beverages menarche |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Ken Ong provided expert comment to Science Media Centre on new paper in Human Reproduction http://humrep.oxfordjournals.org/content/early/2015/01/16/humrep.deu349.short?rss=1 on sugary beverages and age at onset of menstruation http://www.sciencemediacentre.org/expert-reaction-to-study-on-sugary-beverages-and-age-at-onset-of-menstruation/ // KO's comments were quoted in several national and international news reports including the Daily Mail, Guardian, Metro, Irish Times and Herald Scotland. |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.sciencemediacentre.org/expert-reaction-to-study-on-sugary-beverages-and-age-at-onset-of-m... |
Description | Science and 23 & Me Press Releases for paper "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior" |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Covered by more than 300 national and international news outlets, including the Guardian (front page) https://www.theguardian.com/science/2019/aug/29/scientists-quash-idea-of-single-gay-gene, BBC News TV and Online https://www.bbc.co.uk/news/health-49484490, Sun https://www.thesun.co.uk/tech/9823958/sexuality-gay-gene-study/, and Wall Street Journal https://www.wsj.com/articles/research-finds-genetic-links-to-same-sex-behavior-11567101661. John Perry interviewed by New Scientist. Altmetric sciore of 7153 on 20/12/2019 John Perry interviewed by New Scientist https://institutions.newscientist.com/article/2214783-theres-no-such-thing-as-a-gay-gene-finds-largest-study-of-sexuality/ |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.theguardian.com/science/2019/aug/29/scientists-quash-idea-of-single-gay-gene |
Description | Testosterone levels and risk of metabolic disease and cancers |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Cambridge Press Release "Testosterone levels affect risk of metabolic disease and cancers" for Nature Medicine paper 'Using human genetics to understand the disease impacts of testosterone in men and women'. Published on the MRC Epidemiology Unit research news blog and University of Exeter news blog. Shared via unit social media channels. News item submitted to University of Cambridge School of Clinical Medicine newsletter. Reported by the Daily Mail https://www.dailymail.co.uk/health/article-7988161/Women-high-testosterone-levels-37-likely-type-2-diabetes-risk-men-REDUCED.html, and by more than sixty online news outlets, including Reuters, MedicalXpress, Wissenschaft.de, New Atlas, and more than fifty local and regional news outlets via Associated Press. Reported in University of Cambridge School of Clinical Medicine newsletter on 21/02/2020. Altmetric score of 840 on 11/01/2021 https://www.altmetric.com/details/75733162. |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.dailymail.co.uk/health/article-7988161/Women-high-testosterone-levels-37-likely-type-2-d... |
Description | The Conversation - genetic basis of risk taking (EC, FD, KO) |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Conversation article "We uncovered the genetic basis of risk taking - and found it's linked to obesity and mental illness" was reposted on Unit website and shared on social media channels (Twitter, Facebook, LinkedIn), and Republished by MedicalXpress https://medicalxpress.com/news/2018-05-uncovered-genetic-basis-linked-obesity.html and Yahoo News https://uk.news.yahoo.com/uncovered-genetic-basis-risk-taking-143205719.html |
Year(s) Of Engagement Activity | 2018 |
URL | https://theconversation.com/we-uncovered-the-genetic-basis-of-risk-taking-and-found-its-linked-to-ob... |
Description | UKRI MRC press release: Nutritional state regulates growth and age at puberty |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | UKRI-MRC Press release "Scientists discover how our brain uses nutritional state to regulate growth and age at puberty" for paper B. Y. H. Lam, et al. MC3R links nutritional state to childhood growth and the timing of puberty. Nature. University of Michigan also issued press release https://news.umich.edu/scientists-find-new-point-of-access-for-targeting-eating-disorders-and-obesity/. Research news blog posts on MRC Epidemiology Unit, UKRI, IMC-MRL, and University of Michigan websites. IMS-MRL also had piece by Stephen O'Rahilly "The long story on melanocortin regulation of growth and age at puberty: how we did it" https://www.mrl.ims.cam.ac.uk/blog/the-long-story-on-mc3r-regulation-of-growth-and-age-at-puberty-how-we-did-it/. Shared links to articles and paper on MRC Epidemiology Unit Twitter, Facebook, LinkedIn and Instagram channels. Submitted article to University of Cambridge School of Clinical Medicine newsletter. Professor Stephen O'Rahilly interviewed by BBC News (online) https://www.bbc.co.uk/news/health-59140359, BBC Radio 4 (6PM, 3 Nov), BBC World News TV (10 PM, 3 Nov). Also reported by the Daily Mail https://www.dailymail.co.uk/sciencetech/article-10162351/Scientists-brain-receptor-responsible-people-growing-taller-reaching-puberty-earlier.html, Metro https://metro.co.uk/2021/11/04/scientists-discover-why-humans-are-growing-taller-over-time-15540392/, Mirror https://www.mirror.co.uk/science/people-shorter-others-answer-brains-25379194 and ANI https://www.aninews.in/news/science/scientists-discover-how-brain-uses-nutritional-state-to-regulate-growth-age-at-puberty20211103224934/, and at least 30 other online news outlets. Altmetric: https://www.altmetric.com/details/116191656 Paper tweeted by more than 250 Twitter accounts. MRC Epidemiology Unit blog post 142 unique views. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ukri.org/news/how-our-brain-uses-nutritional-state-to-regulate-growth/ |
Description | US News and world report - healthiest month |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Interviewed and quoted in online article "What's the Healthiest Month to Be Born In?" in U.S News and World Report http://health.usnews.com/wellness/slideshows/whats-the-healthiest-month-to-be-born-in. |
Year(s) Of Engagement Activity | 2016 |
URL | http://health.usnews.com/wellness/slideshows/whats-the-healthiest-month-to-be-born-in |
Description | Unit blog article - Genetics study links early male puberty to shorter lifespan and darker hair colour |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Unit news blog post "Genetics study links early male puberty to shorter lifespan and darker hair colour". Shared on Unit Twitter, Facebook and LinkedIn accounts. Also posted on 23andMe news blog. Reported by seven online Russian news outlets. Tweeted by 26 twitter users. |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.mrc-epid.cam.ac.uk/blog/genetics-early-male-puberty-shorter-lifespan/ |
Description | University of Cambridge Press Release - Hand Grip Strength |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Cambridge press release on Nature communications paper "Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness" by Sara Willems et al. Also published on University of Cambridge and MRC Epidemiology Unit research news blogs. Article in print edition of iNewspaper, and also reported in 12 national and international science and health news outlets , including Medical News Today and Sci News. Author Dan Wright interviewed by BBC Radio Cambridgeshire on Morning Show with Dotty McLeod on 18/07/2017. Evidence of impact: https://in.news.yahoo.com/genetic-factors-linked-strength-identified-122605949.html, https://www.genengnews.com/gen-news-highlights/hand-grip-strength-genes-could-aid-development-of-drugs-for-myopathies/81254640, https://www.topsante.com/medecine/votre-sante-vous/sante-pratique/la-force-musculaire-identifiee-dans-les-genes-619595 |
Year(s) Of Engagement Activity | 2017 |
URL | https://www.eurekalert.org/pub_releases/2017-07/uoc-cs071117.php |
Description | University of Cambridge press release - Rare genetic variants |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Cambridge press release 'Rare genetic variants confer largest increase in type 2 diabetes risk seen to date' for paper Yajie Zhao et al. GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health. Nature Communications. 07 July 2021 https://doi.org/10.1038/s41467-021-24504-y. News article published on Unit website https://www.mrc-epid.cam.ac.uk/blog/2021/07/07/rare-genetic-variants-largest-increase-t2dm/ and shared on Unit social media channels. Article submitted to University of Cambridge School of Clinical Medicine Newsletter John Perry quoted in Daily Mail article https://www.dailymail.co.uk/sciencetech/article-9764913/Gene-increase-risk-Type-2-diabetes-six-fold-study-finds.html and iNews https://inews.co.uk/news/health/scientists-discover-genetic-variant-type-2-diabetes-1091483. Published in at least 14 online medical and science news outlets. Article in 9 July issue of University of Cambridge School of Clinical Medicine Newsletter. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.cam.ac.uk/research/news/rare-genetic-variants-confer-largest-increase-in-type-2-diabetes... |
Description | University of Exeter - Reproductive lifespan in women |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Exeter press release "Researchers identify new genes linked to longer reproductive lifespan in women" for paper "Genetic insights into biological mechanisms governing human ovarian ageing. Ruth K.S. et al. Nature. 04 August 2021. DOI:10.1038/s41586-021-03779-7". John Perry took part in online press briefing on 3 August 2021 organised by Nature. News post on Unit website, and link to paper and commentary shared and re-tweeted on Unit social media channels. Article submitted to University of Cambridge School of Clinical Medicine newsletter. John Perry was quoted in several print news articles, including the Guardian, Telegraph, I, Independent and Mail. Paper reported online by more than 260 news outlets in more than 37 countries, including Guardian https://www.theguardian.com/society/2021/aug/04/genetic-secret-to-age-women-start-menopause-discovered, Telegraph https://www.telegraph.co.uk/news/2021/08/04/menopause-delaying-gene-found-raising-hopes-extending-fertility/, Sun https://www.thesun.co.uk/fabulous/15780311/new-test-predict-risk-early-menopause-if-start-family/, HuffPost https://ca.sports.yahoo.com/news/fertility-doctors-could-soon-tell-150006631.html, New Scientist https://institutions.newscientist.com/article/2285966-study-of-how-genes-influence-menopause-may-improve-fertility-treatment/, Irish News, El Pais. La Republica. Paper tweeted by more than 300 Twitter accounts by 09/8/21 https://www.altmetric.com/details/111125337/twitter. Item in University of Cambridge School of Clinical Medicine newsletter on 20 August. |
Year(s) Of Engagement Activity | 2021 |
URL | http://www.exeter.ac.uk/news/research/title_870643_en.html |
Description | University of Oxford - Genetics and age at first sex and birth |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Oxford Press Release "Genetics plays important role in age at first sex and birth with links to dis-inhibition, longevity and disease", accompanied by FAQ. News article published on Unit website https://www.mrc-epid.cam.ac.uk/blog/2021/07/01/genetics-age-first-sex-birth/ and shared on Unit Twitter, Facebook and LinkedIn accounts. Article submitted to University of Cambridge School of Clinical Medicine Newsletter. Reported in the Daily Mail https://www.dailymail.co.uk/sciencetech/article-9745237/When-lose-virginity-written-genes.html and New York Post https://nypost.com/2021/07/01/when-you-lose-your-virginity-may-be-up-to-your-genes-study/ and at least 14 online news outlets. Nature Human Behaviour paper tweeted by more than 100 twitter accounts. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ox.ac.uk/news/2021-07-01-genetics-plays-important-role-age-first-sex-and-birth-links-dis... |
Description | UoM press release |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | University of Michigan Press Release on paper "Genetic studies of body mass index yield new insights for obesity biology"; http://www.uofmhealth.org/news/archive/201502/largest-ever-genome-wide-study-strengthens-genetic-link. Felix Day, Claudia Langenberg, Jian'an Luan, John Perry, Ken Ong, Jing Hua Zhao, Nita Forouhi, Ruth Loos, Nick Wareham. // 50+ reports in National and International print and online media // http://www.theguardian.com/society/2015/feb/11/obesity-genes-help-determine-size-and-shape-studies-find |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.uofmhealth.org/news/archive/201502/largest-ever-genome-wide-study-strengthens-genetic-lin... |
Description | Utah Press release - Genetics of PCOS (JP, FD) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Felix Day answered questions from charity PCOS Challenge, and Corinne Welt was interviewed by Newsweek. University of Utah Health Press Release "Researchers identify genes associated with polycystic ovary syndrome". Reported in more than 25 online outlets, including several specialist medical and science outlets uch as MedicalXpress https://medicalxpress.com/news/2018-12-genes-polycystic-ovary-syndrome.html and GenomeWeb https://www.facebook.com/permalink.php?story_fbid=1823095294468459&id=113339508777388 |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.eurekalert.org/pub_releases/2018-12/uouh-rig121318.php |
Description | Visiting Pepper Professor - Harvard Medical School (JP) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Dr John Perry gave a lecture as the Pepper Visiting Professor of Medicine at Harvard Medical School. |
Year(s) Of Engagement Activity | 2018 |
Description | Women's Health campaign |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Invited to write short article (700 characters) for Women's Health campaign organized by Media Planet in association with Guardian. |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.womenshealthadvice.co.uk/fertility-and-pregnancy/genetic-studies-illuminate-the-connectio... |