The Airwave Health Monitoring Study (AHMS). An Occupational Cohort Study of the British Police Forces.

Lead Research Organisation: Imperial College London
Department Name: School of Public Health

Abstract

Police officers are among one of the occupational groups presenting with higher rates of ill health compared to other workers and are exposed to a wide range of chemical, physical and psychosocial risk factors that can affect their health and performance at work. This raises questions about how the risk factors they face at work affects their performance and ultimately their wellbeing and safety, as well as the safety of the public. Recent staff surveys and literature have indicated that mental health issues, such as anxiety and depression, are also a particular concern. Understanding these hazards and risks to police officer health and putting tailored safety and health promotion measures in place is an obvious solution. However, there is a lack of detailed information on the specific factors involved and the how these, individually or in combination, affect health. It is also likely that health outcomes vary according to workplace factors (e.g. region, rank, hours worked) but also vary according to individual make-up and sociodemographic characteristics. Therefore, understanding and quantifying risk factors to police officer health may impact on the health and wellbeing of the individual, their colleagues and families as well as on the health of the public.

The Airwave Health Monitoring Study (AHMS) was established to evaluate possible health risks associated with the use of the digital communication system used by the police forces and other emergency services. It is a large (over 50,000 participants) long-term study investigating the health of police officers and staff across Great Britain. Currently, follow-up measures are being undertaken in England only. Our objectives are both to extend the follow-up of the AHMS to Scotland and Wales, and to provide a resource for studying how gender, lifestyle, and occupational exposures interact with genetic and metabolic factors in relation to physical and mental health, in a comparatively young working population with a high representation of men.

Specifically we plan to:

i) follow-up the Scottish and Welsh AHMS participants who attended a baseline clinical assessment (N = 13,681) approximately 7.5 years later;
ii) develop a method to estimate exposures to a range of chemical, physical and psychosocial risk factors to health by combining group level data through a bespoke Job Exposure Matrix (JEM) and individual level data to refine and evaluate JEM performance.
iii) use mental health as an exemplar case study to examine the relationships between work-related risk factors and mental health difficulties, and identify the individual and/or workplace 'protective' factors that promote wellbeing within the workplace.

Our proposal has high policy relevance at the level of both government and employers. It represents a novel, cross-sectoral collaboration between academics across five UK leading universities and in partnership with police forces and the Police Federation (representing rank and file officers) across Great Britain. The application has wide support from our stakeholders who have been included in the project from the outset in order to ensure that the findings are translated into interventions that impact on health and wellbeing.

Technical Summary

The Airwave Health Monitoring Study (AHMS) is a long-term cohort study of the health of police officers and staff across Great Britain. With funding from Home Office (ends March 2018), it has recruited 53,280 individuals of whom 45,533 have had clinical and biological measurements collected as part of a baseline clinical assessment, with data linkage of the cohort to routine NHS records. The aim of the current proposal is to greatly augment the AHMS cohort through further face-to-face clinical follow-up in Scotland and Wales (follow-up in England is funded separately), and to provide a resource for studying how gender, lifestyle, and occupational exposures interact with genetic and metabolic factors in relation to physical and mental health. We will do this via: i) follow-up assessment at c. 7.5 years of Scottish and Welsh Airwave participants (N = 13,681) aiming for 40% participation rate based on extensive pilot studies; ii) development of a methodology for obtaining estimates of exposure to a range of chemical, physical and psychosocial risk factors that may be associated with chronic disease or reduced health and wellbeing, using a combination of estimates on group level through development of bespoke Job Exposure Matrices (JEMs), with self-reported and objective individual exposure measures (e.g. from analyses of available computerised records from the police TETRA radio system, which informs on individual shift work patterns); and iii) an exemplar case study to examine the reciprocal relationships between operational and organisational risk factors and mental health difficulties, and identify what factors promote resilience within the workplace. This proposal if funded will provide a unique resource for research on occupational health among a 'front-line' public-facing service and provide the evidence-base for interventions to improve health and well-being among the workforce.

Planned Impact

The Airwave Health monitoring study (AHMS) is the only large-scale cohort study of police employees worldwide. It includes a group of younger men aged under 40 who are under-represented in the UK research portfolio. As it has proven difficult to interest this group in primary prevention and there is only limited routine contact with primary care, engaging with this demographic group helps fill a gap and boosts the value and impact of UK population cohorts as a whole.
Development of a set of Job Exposure Matrices (JEMs) to obtain greater understanding of workplace exposures experienced by Police Force employees would have wider applicability to other 'front-line' occupations, and would strengthen UK capability in this area of research.

The cohort has been richly phenotyped, flagged to routine records, and provides an excellent, unique resource to study the genetic, metabolic, occupational and lifestyle factors associated with physical and mental health, including cognitive performance, among a predominantly male and young adult workforce with a well-defined organisational hierarchy. Whilst the particular focus of the AHMS is the police force and related staff, the questions that can be asked of the resource can yield answers that are generalizable to workers in other occupational groups, especially those required to deal with stressful situations in high-demand, shift-based, structured work environments (e.g. health service, prison and fire services). The results therefore could have important impact on the working practices, and mental and physical health, of workers in a range of 'public facing' occupations.

The proposed research will address a number of areas and domains, where the findings could have important implications for working practice and lead to possible work-place interventions:

a. Studying how gender, lifestyle, and occupational exposures interact with genetic and metabolic factors in relation to the development of physical and mental health issues, will contribute to better understanding of risk factors for poor health, and possible remediation approaches
b. Gaining greater awareness of social differentials between job assignments and the impact of stress and job strain on health could have direct impact on day-to-day working arrangements, as well as the consequence of highly stressful events and shift working patterns
c. Absence from work through sickness constitutes a huge economic burden for the UK Police Force, and contributes to the poor productivity of the UK workforce in general. The AHMS has collected sickness absence records from participating police forces, and linked those data with clinical, lifestyle, genetic and metabolic information on a large sample of Police Force employees. Using this resource, the AHMS offers unique opportunity to gain much greater understanding of the drivers of absenteeism in the Police Force, with potential for substantial health and economic benefit if even a small downward shift in numbers of days absent could be achieved. By identifying and remediating the drivers of the large degree of absenteeism through sickness, there is potential to develop successful interventions targeting the most important modifiable determinants.
d. The AHMS participants have consented to recall into studies by genotype and/or phenotype. The cohort could become a rich source of participants for trials of behavioural and other interventions on mental health and other outcomes, potentially leading to new or improved treatments for these conditions in a work-place setting.

Publications

10 25 50
publication icon
Aljuraiban GS (2023) Lifestyle Score and Risk of Hypertension in the Airwave Health Monitoring Study of British Police Force Employees. in International journal of environmental research and public health

publication icon
Bauermeister S (2020) The Dementias Platform UK (DPUK) Data Portal. in European journal of epidemiology

publication icon
Dehghan A (2022) Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer's disease. in Proceedings of the National Academy of Sciences of the United States of America

 
Title People like you: Contemporary Figures of Personalisation 
Description People Like You' presented an online conversation about Stefanie Posavec's visualisation of the Airwave study and how work like hers can be useful for cohorts and biobanks. As part of our Wellcome Trust Medical Humanities Collaborative award, "People Like You: contemporary figures of personalisation," Stefanie Posavec worked as an artist-in-residence exploring data science and personalisation through visualisation of the Airwave Health Monitoring Study. As a part of this project, the People Like You team invited people who work with research cohorts and biobanks, people who participate in them, and people whose work focuses on these topics to hear a brief presentation of Stefanie's method, reactions from some of those who participated in her practice, and a Q&A discussion about how her work might be useful in other contexts. 
Type Of Art Artwork 
Year Produced 2021 
Impact Not known 
URL http://police-health.org.uk/news/stefanie-posavecs-visualisation-airwave-study
 
Description Enhancement of Generation Malawi
Amount £216,000 (GBP)
Organisation United Kingdom Research and Innovation 
Sector Public
Country United Kingdom
Start 02/2022 
End 03/2022
 
Description Exploiting genomic approaches to identify the environmental basis of depression
Amount £2,530,384 (GBP)
Funding ID 220857/Z/20/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2021 
End 05/2026
 
Description Exploiting genomic approaches to identify the environmental basis of depression
Amount £2,530,384 (GBP)
Funding ID 220857 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2021 
End 12/2025
 
Description The Airwave Health Monitoring Study (AHMS). An Occupational Cohort Study of the British Police Forces.
Amount £1,988,965 (GBP)
Funding ID MR/R023484/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 07/2018 
End 06/2023
 
Title Airwave Health Monitoring Study 
Description The Airwave Health Monitoring Study was established to evaluate possible health risks associated with the use of TETRA, a digital communication system used by the police forces and other emergency services in Great Britain since 2001. It is a long-term observational study following up the health of the police force with respect to TETRA exposure, and ability to monitor both cancer and non-cancer health outcomes. The Airwave Health Study Tissue Bank completed its recruitment in March 2015, thus establishing a "baseline" for the cohort. We are currently carrying out a programme of re-screening of existing cohort members that were already screened at baseline. 
Type Of Material Biological samples 
Year Produced 2015 
Provided To Others? No  
Impact We continue to collaborate with researchers both within Imperial College and external, sharing samples and data from our health screening. From June till December 2019, we completed 1,839 follow-up screens on 1,789 participants. As of 26th Feb 2020, the current number of active members of the Tissue Bank is 53,243, whose mean number of years of membership is 10.3. We have recently used 91 blood samples during the year for DNA extractions and genotyping, work on which is ongoing. More are planned for 2020. 
 
Title Absences from Employment (Annex D) 
Description The absences dataset is a single file that contains a set of records, each of which reports a participant's absence from their normal police duties. Most absences are for health-reasons, but other reasons exist. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2023 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
URL https://police-health.org.uk/sites/default/files/2023-03/annex-d.pdf
 
Title Cognitive Testing Results 
Description Outcome variables for each test are reported. The file includes N=14,720 participants who did the follow-up cognitive test during the health screening in one of Airwave clinics. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
 
Title Diet Analysis 
Description This dataset is the results of entering the 7-day food-diaries that participants complete into Dietplan, a software package that provides nutritional breakdowns of recipe, meals, menus and personal weighed-intake food diaries. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
URL https://www.foresoft.co.uk/html/about.html
 
Title Electrocardiogram (ECG) Export (Annex C) 
Description Data available from the Airwave Study Tissue Bank electrocardiogram ECG export. The reader should consult the main data-dictionary for a description of the screening protocol itself, explanations of formatting conventions, missing values, and other technical information. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
URL https://police-health.org.uk/sites/default/files/2022-05/annex-c.pdf
 
Title Employments Export (Annex B) 
Description Each record is a single observation of basic details about a participant's employment circumstances. Many participants will have several records over time. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2023 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
URL https://police-health.org.uk/sites/default/files/2022-05/annex-b.pdf
 
Title Interpretation of Data Fields Derived from the Screening Protocol (Annex A) 
Description This Annex lists the data-fields available from the Airwave Study Tissue Bank screening protocol. The reader should consult the main data-dictionary for a description of the screening protocol itself, explanations of formatting conventions, missing values, and other technical information. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2023 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
URL https://police-health.org.uk/sites/default/files/2022-05/annex-a.pdf
 
Title Results of Genomic Assays of Airwave Participants 
Description We have carried out GWAS assays of c. 24000 participants in the Airwave study. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2023 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
 
Title Self-Administered Surveys 
Description This dataset is the final set of clinic-based survey results completed by participants attending an Airwave health-screen. It includes a wide-ranging set of questions about participants use of the Airwave system, existing diagnoses of health conditions and mental health state. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
URL https://police-health.org.uk/sites/default/files/2020-04/airwave-variables.xlsx
 
Title Treatments and Medications 
Description The treatments and medications dataset is a single file, each record of which is a medication (or occasionally a treatment) that participants reported that they were taking at the time of their clinic visit. Although we asked participants and nurses to limit themselves to prescription medicines prescribed by a doctor, the dataset also contains non-prescription drugs available over the counter at pharmacies, and all kinds of self-help potions and supplements. We sought only the drug name, not dosage or other prescribing details. When participants forgot to bring this information with them, we recorded whatever they reported to us. To obtain access to the resource, prospective researchers must provide a brief proposal of their project. We may ask for proof of peer review to help confirm that the proposed research is scientifically feasible and ethically sound. The Access Committee will assess the merits of each request to ensure that the research meets the overall objectives of the Tissue Bank, and that the confidentiality and ethical issues commitments made to participants have been fulfilled. 
Type Of Material Database/Collection of data 
Year Produced 2023 
Provided To Others? Yes  
Impact This dataset has been uploaded to the Dementias Platforms UK Trusted Research Environment where it is available to be accessed by researchers upon application. 
 
Description Airwave - Police Federation of England and Wales 
Organisation Police Federation of England and Wales
Country United Kingdom 
Sector Public 
PI Contribution Scientific conduct of the study and close liaison with the Federation to ensure continuing support for participation
Collaborator Contribution Collaboration on the Airwave study steering committee and access committee - lay contribution to these committees and assistance with communication channels to police organisation contacts to improve effectiveness of study implementation.
Impact ongoing collaboration
Start Year 2018
 
Description Airwave Collaboration with the PGC 
Organisation Psychiatric Genomics Consortium (PGC)
Country Global 
Sector Learned Society 
PI Contribution The genetic data from the Airwave cohort is being incorporated into the forthcoming genome-wide association analyses of depression and anxiety disorders, in collaboration with the Psychiatric Genomics Consortium (PGC)
Collaborator Contribution The PGC will securely store the summary association statistics from Airwave and include it in a genome wide meta-analysis with other studies from around the world. They will also provide genetic risk scores for depression in all Airwave participants, allowing Airwave investigators to assess whether this predicts work place absenteeism and satisfaction in individuals with or without depression.
Impact No outputs so far
Start Year 2019
 
Description Airwave and CARDIA cohorts collaboration on metabolic pathways and blood pressure and body weight index 
Organisation University of North Carolina at Chapel Hill
Country United States 
Sector Academic/University 
PI Contribution Potentially we will contribute data from the Airwave cohort study to the proposed analysis, and expertise in data interpretation.
Collaborator Contribution Partner is sourcing funding for the proposed work and will bring data from the CARDIA cohort study to the project and expertise in nutrition and obesity.
Impact Data access applied for and grant application written and under consideration.
Start Year 2019
 
Description Airwave and CCACE - Centre for Cognitive Ageing and Cognitive Epidemiology 
Organisation University of Edinburgh
Department MRC Centre for Cognitive Ageing and Cognitive Epidemiology
Country United Kingdom 
Sector Academic/University 
PI Contribution Data collection, data quality control and analysis and database management
Collaborator Contribution Working with to enhancement baseline data collection with addition of questions on mental health and cognition to enable future analysis of work-related stressors
Impact ongoing collaboration
Start Year 2018
 
Description Airwave and MRC CSO Social and Public Health Sciences Unit 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of Airwave study data and biosamples for analysis
Collaborator Contribution Expertise in occupational work exposures and evaluation of work place interventions for health promotion
Impact ongoing collaboration
Start Year 2018
 
Description Airwave and occupational exposure assessment 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution Airwave study data and biosamples
Collaborator Contribution Collaborating with the Centre for Occupational and Environmental Health with expertise in occupational exposure assessment. Obtaining expert advice on the formation and use of a job exposure metrix (JEM) for the study
Impact ongoing collaboration
Start Year 2019
 
Description Airwave collaboration with CIPHER and SAIL databank 
Organisation Swansea University
Department Centre for Improvement in Population Health through E-records Research (CIPHER)
Country United Kingdom 
Sector Academic/University 
PI Contribution Airwave study cohort participant data and database and expertise in secure database management
Collaborator Contribution Secure data linkage and data hosting in SAIL databank and expertise in processing and storage of electronic health data records
Impact ongoing collaboration
Start Year 2018
 
Description Airwave collaboration with DPUK - Dementia Platforms UK 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Collection and provision of Airwave study data. Airwave data collected by the study team is being uploaded into the DPUK data portal so that it is available to other researchers. Collaboration with Prof Gallacher, PI of DPUK on pilot use of data including CSR pilot, collaborative grant applications and publications.
Collaborator Contribution DPUK portal coordination and data access procedures
Impact ongoing collaboration
Start Year 2018
 
Description Airwave collaboration with DPUK - Great Minds pilot study 
Organisation MRC Dementias Platform UK
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with DPUK to invite Airwave study participants to take part in the Great Minds pilot study. Facilitated contact with study participants.
Collaborator Contribution Coordination of Great Minds pilot study
Impact new collaboration - ongoing
Start Year 2019
 
Description Airwave collaboration with DPUK and SAIL 
Organisation Swansea University
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of Airwave study data and expertise in database management and health data linkage
Collaborator Contribution SAIL Databank is being used as a means of secure data processing and storage for study data
Impact ongoing collaboration
Start Year 2018
 
Description Airwave collaboration with UK Biobank 
Organisation UK Biobank
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution We have initiated an amendment to UK Biobank project 4844 to allow Airwave to be linked to UK Biobank using genetic checksums, allowing overlapping individuals to be removed from analyses that utilise both datasets
Collaborator Contribution UK Biobank have provided genetic data and information on depression and anxiety to facilitate this collaboration
Impact None so far
Start Year 2019
 
Description Blood cell genetics project 
Organisation Montreal Heart Institute
Country Canada 
Sector Hospitals 
PI Contribution Samples and data from Airwave cohort study
Collaborator Contribution Conducted meta-analysis including Airwave data
Impact Published paper Chen et al 2020 Cell
Start Year 2019
 
Description Blood cell genetics project 
Organisation National Institutes of Health (NIH)
Department National Heart, Lung, and Blood Institute (NHLBI)
Country United States 
Sector Public 
PI Contribution Samples and data from Airwave cohort study
Collaborator Contribution Conducted meta-analysis including Airwave data
Impact Published paper Chen et al 2020 Cell
Start Year 2019
 
Description Blood pressure traits project 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Samples and data from Airwave cohort study, data provision
Collaborator Contribution Conducted genome-wide discovery analysis including the Airwave data
Impact Published paper Vuckovic et al Cell 2020
Start Year 2019
 
Description Cardiovascular health and Airwave collaboration - Glasgow 
Organisation Glasgow Royal Infirmary
Country United Kingdom 
Sector Hospitals 
PI Contribution Contributing data from the Airwave cohort study and ECG trace data
Collaborator Contribution Expertise in analysis of ECG trace data and data interpretation in relation to cardiovascular health and wellbeing.
Impact ongoing collaboration
Start Year 2019
 
Description Collaboration with the PGC 
Organisation Psychiatric Genomics Consortium (PGC)
Country Global 
Sector Learned Society 
PI Contribution McIntosh and one of the post-doctoral fellows (Adams) have shared data and expertise with the Psychiatric Genomics Consortium (PGC). AIRWAVE have contributed genetic and phenotypic data to the next major MDD GWAS update
Collaborator Contribution The PGC have supplied analysts and expertise to work on and expand the use of the data collected from Generation Scotland. It is estimated that so far this would amount to one year's worth of post-doctoral research fellow time over the duration of the award
Impact All publications with the Psychiatric Genomics Consortium byline authorship are relevant to this contribution. In particular, two publications particularly highlight the value of this work: Wray (Nature Genetics, 2018) and Howard (Nature Neuroscience, 2019). The Edinburgh investigators led the second of these publication, which is in the top 1% of all papers in Nature Neuroscience by citation/download numbers, of a similar date.
Start Year 2018
 
Description DPUK data portal pilot study - Airwave 
Organisation MRC Dementias Platform UK
Country United Kingdom 
Sector Academic/University 
PI Contribution Airwave cohort study data is being uploaded into the national DPUK data portal and the study was selected to take part in the pilot launch of the data platform.
Collaborator Contribution Facilitated inclusion of the cohort data into the data platform with potential to share anonymised data with research partners.
Impact Scientific paper published Baumeister et al Eur J Epidemiol 2020
Start Year 2019
 
Description DPUK data portal pilot study - Airwave 
Organisation Swansea University
Department Swansea University Medical School
Country United Kingdom 
Sector Academic/University 
PI Contribution Airwave cohort study data is being uploaded into the national DPUK data portal and the study was selected to take part in the pilot launch of the data platform.
Collaborator Contribution Facilitated inclusion of the cohort data into the data platform with potential to share anonymised data with research partners.
Impact Scientific paper published Baumeister et al Eur J Epidemiol 2020
Start Year 2019
 
Description DPUK data portal pilot study - Airwave 
Organisation University of Oxford
Department Department of Psychiatry
Country United Kingdom 
Sector Academic/University 
PI Contribution Airwave cohort study data is being uploaded into the national DPUK data portal and the study was selected to take part in the pilot launch of the data platform.
Collaborator Contribution Facilitated inclusion of the cohort data into the data platform with potential to share anonymised data with research partners.
Impact Scientific paper published Baumeister et al Eur J Epidemiol 2020
Start Year 2019
 
Description Dietary Intake and Association with Cardiometabolic Risk 
Organisation King's College London
Department Department of Nutrition and Dietetics
Country United Kingdom 
Sector Academic/University 
PI Contribution Cohort data curation and analysis, statistical analysis
Collaborator Contribution KCL - Analysis of diet diary data for Airwave sample, dietetic expertise; Uni Colorado - study concept and design and data analysis, drafted manuscript; Massachusetts - dietary and nutrient analysis and advice
Impact Published paper Hunt et al Nutrients 2020
Start Year 2018
 
Description Dietary Intake and Association with Cardiometabolic Risk 
Organisation Massachusetts General Hospital
Department Center for Genomic Medicine
Country United States 
Sector Hospitals 
PI Contribution Cohort data curation and analysis, statistical analysis
Collaborator Contribution KCL - Analysis of diet diary data for Airwave sample, dietetic expertise; Uni Colorado - study concept and design and data analysis, drafted manuscript; Massachusetts - dietary and nutrient analysis and advice
Impact Published paper Hunt et al Nutrients 2020
Start Year 2018
 
Description Dietary Intake and Association with Cardiometabolic Risk 
Organisation University of Colorado Boulder
Country United States 
Sector Academic/University 
PI Contribution Cohort data curation and analysis, statistical analysis
Collaborator Contribution KCL - Analysis of diet diary data for Airwave sample, dietetic expertise; Uni Colorado - study concept and design and data analysis, drafted manuscript; Massachusetts - dietary and nutrient analysis and advice
Impact Published paper Hunt et al Nutrients 2020
Start Year 2018
 
Description Gene and educational attainment and BP project 
Organisation University of Washington
Country United States 
Sector Academic/University 
PI Contribution Airwave cohort samples for genome-wide meta-analysis, data provision
Collaborator Contribution Study design and conducted meta-analysis
Impact Published paper de las Fuentes et al 2020 Mol Psychiatry
Start Year 2019
 
Description Gene variants and blood pressure regulation 
Organisation University of Cambridge
Department Cardiovascular Epidemiology Unit
Country United Kingdom 
Sector Academic/University 
PI Contribution Data and samples from Airwave cohort
Collaborator Contribution Carried out discovery meta-analysis to identify genetic variants associated with BP
Impact Published paper Surendran et al Nature Genetics 2020
Start Year 2019
 
Description Mental health in the police force and Airwave collaboration 
Organisation King's College London
Department King's Centre for Military Health Research
Country United Kingdom 
Sector Public 
PI Contribution Data from the Airwave cohort study and epidemiological expertise in data interpretation
Collaborator Contribution Expertise in assessment of mental health status and trauma exposure.
Impact Scientific paper submitted and under consideration for publication.
Start Year 2019
 
Description Metabolomic and epigenetic ageing project 
Organisation University of Oulu
Department Biocenter Oulu
Country Finland 
Sector Academic/University 
PI Contribution Study concept and design, data curation and analysis, AIRWAVE data acquisition, drafted paper
Collaborator Contribution Data and metabolomic analysis of NFBC cohort
Impact Published paper Robinson O et al. Ageing Cell doi: 10.1111/acel.13149
Start Year 2020
 
Description PTSD, depression and anxiety in police force 
Organisation King's College London
Department King's Centre for Military Health Research
Country United Kingdom 
Sector Public 
PI Contribution Epidemiological expertise and data from Airwave cohort
Collaborator Contribution Expertise in health effects of mental disorders in military/army cohorts with similar stressors
Impact published paper Stevelink et al PLOS One 2020
Start Year 2018
 
Description PhD studentship in sleep and health 
Organisation Medical Research Council (MRC)
Department MRC Social & Public Health Sciences Unit
Country United Kingdom 
Sector Academic/University 
PI Contribution Joint application for funding and offer of joint PhD student supervision
Collaborator Contribution Coordination of joint application for funding and offer of primary PhD student supervision
Impact studentship being advertised
Start Year 2018
 
Description REACT-Siemens project (COVID-19) 
Organisation Siemens Healthcare
Country Germany 
Sector Private 
PI Contribution We are inviting members of the Airwave cohort living nearby to the assessment centre in London to assess the usability/reliability of novel methods to collect blood and saliva for antibody testing for COVID-19.
Collaborator Contribution Provision of laboratory-based SARS-CoV-2 antibody tests
Impact active project
Start Year 2020
 
Description Sleep and health project 
Organisation Home Office
Country United Kingdom 
Sector Public 
PI Contribution Host of Airwave cohort data and samples - proposal to study sleep patterns, work factors and health; study concept and design
Collaborator Contribution Potential call data records from HO and funding for analysis
Impact proposal under consideration
Start Year 2020
 
Description The Consortium of Metabolomics Studies (COMETS) and Airwave 
Organisation Brigham and Women's Hospital
Country United States 
Sector Hospitals 
PI Contribution Contributing data from the Airwave cohort to this consortium of 47+ international cohorts
Collaborator Contribution Platform for sharing data to facilitate large-scale collaborative research e.g. meta-analysis and GWAS on the human metabolome
Impact Publication Yu et al Am J Epidemiol 2019 https://doi.org/10.1093/aje/kwz028 .
Start Year 2019
 
Description The Consortium of Metabolomics Studies (COMETS) and Airwave 
Organisation National Cancer Institute
Country Lithuania 
Sector Hospitals 
PI Contribution Contributing data from the Airwave cohort to this consortium of 47+ international cohorts
Collaborator Contribution Platform for sharing data to facilitate large-scale collaborative research e.g. meta-analysis and GWAS on the human metabolome
Impact Publication Yu et al Am J Epidemiol 2019 https://doi.org/10.1093/aje/kwz028 .
Start Year 2019
 
Title Acceptability, usability and performance of lateral flow immunoassay tests for SARS-CoV-2 antibodies: REACT-2 study of self-testing in non-healthcare key workers 
Description Background Seroprevalence studies in key worker populations are essential to understand the epidemiology of SARS-CoV-2. Various technologies, including laboratory assays and point-of-care self-tests, are available for antibody testing. The interpretation of seroprevalence studies requires comparative data on the performance of antibody tests. Methods In June 2020, current and former members of the UK Police forces and Fire service performed a self-test lateral flow immunoassay (LFIA) and provided a saliva sample, nasopharyngeal swab, venous blood samples for Abbott ELISA and had a nurse performed LFIA. We present the prevalence of PCR positivity and antibodies to SARS-CoV-2 in this cohort following the first wave of infection in England; the acceptability and usability of self-test LFIAs (defined as use of the LFIA kit and provision of a valid result, respectively); and determine the sensitivity and specificity of LFIAs compared to laboratory ELISAs. Results In this cohort of non-healthcare key workers, 7.4% (396/5,348; 95% CI, 6.7-8.1) were antibody positive. Seroprevalence was 8.9% (6.9-11.4) in those under 40 years, 11.5% (8.8-15.0) in those of non-white British ethnicity and 7.8% (7.1-8.7) in those currently working. The self-test LFIA had an acceptability of 97.7% and a usability of 90.0%. There was substantial agreement between within-participant LFIA results (kappa 0.80; 0.77-0.83). The LFIAs (self-test and nurse-performed) had a similar performance: compared to ELISA, sensitivity was 82.1% (77.7-86.0) self-test and 76.4% (71.9-80.5) nurse-performed with specificity of 97.8% (97.3-98.2) and 98.5% (98.1-98.8) respectively. 
Type Diagnostic Tool - Non-Imaging
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2020
Development Status On hold
Impact Conclusion A greater proportion of the non-healthcare key worker cohort showed evidence of previous infection with SARS-CoV-2 than the general population at 6.0% (5.8-6.1) following the first wave in England. The high acceptability and usability reported by participants and the similar performance of self-test and nurse-performed LFIAs indicate that the self-test LFIA is fit for purpose for home-testing in occupational and community prevalence studies. 
URL https://www.medrxiv.org/content/10.1101/2021.06.21.21259254v2
 
Description British APCO - Presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact In March 2019, our research fellow, Dr He Gao, presented a lay summary of the recent research results of the Airwave Study at BAPCO, "the leading UK based Association for all professionals using or developing Public Safety technology."
Year(s) Of Engagement Activity 2019
 
Description Contemporary Figures of Personalisation - public in person event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact On September 17th 2021 the People Like You team held a public event at Kings Place, London, on Contemporary Figures of Personalisation. It was an opportunity to showcase some of the work of the project, including presentations from three artists in residence, and to discuss key issues in personalisation across a range of sectors. There were discussions about personalisation in health, policy, advertising, social media and more. Professor Deborah Ashby (Director of the School of Public Health) was part of a panel discussing how personalisation is understood and practised in different sectors. Stefanie Posavec has worked as an artist-in-residence exploring data science and personalisation through visualisation of the Airwave Health Monitoring Study. Her artwork Data Murmurations: Points in flight was created following interviews with Airwave Study participants and staff, including the Principle Investigator.
Following this event there was a full launch of Stef's work, plus some stakeholder meetings to discuss how the work helps engage people with the complexity of biobanks and cohort research. Wellcome Trust and others were interested in using Stef's work, which has all been good publicity for Airwave Health Monitoring Study.
Year(s) Of Engagement Activity 2021
URL https://peoplelikeyou.ac.uk/blog/those-shoes-that-follow-you-round-the-internet-contemporary-figures...
 
Description Depression talk to Department of Work and Pensions 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Discussion about depression, its causes and consequences, how it is managed - including how it is managed in the workplace. Discussed the need for more research, giving the Airwave study as an example, and the need to access routinely collected administrative data as part f HDR UK activities such as DATAMIND
Year(s) Of Engagement Activity 2022
 
Description Law Enforcement and Public Health (LEPH) conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact On the 21-23rd October 2019, we presented a poster at the Law Enforcement and Public Health (LEPH) conference in Edinburgh, Scotland. This is a biennial conference exploring the complex and diverse intersections of law enforcement and public health, involving practitioners, policy makers and researchers from these and other related sectors.
Year(s) Of Engagement Activity 2019
 
Description National Institute for Health research (NIHR) Imperial Research open day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Policymakers/politicians
Results and Impact To enrich our public engagement activities we took part in the National Institute for Health research (NIHR) Imperial Research open day on the 15th November 2019 at the W12 conferences in Hammersmith Hospital. The aim was to promote meaningful conversations about the work we do to a wide audience consisting of carers, patients, research and healthcare professionals as well as members of the public.
Year(s) Of Engagement Activity 2019
 
Description Newsletter to Airwave Study Participants 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact We sent a newsletter to all members of the cohort primarily to advise them that Airwave is taking part in the UK Longitudinal Linkage Collaboration ("UK LLC"). The newsletter highlighted the Airwave Study's contribution to COVID-19 research, recently completed research results, ongoing and future work and the Airwave inspired artwork Data Murmurations: Points in flight by Stefanie Posavec. It also promoted the follow-up programme and our duty to help save the planet by asking participants to provide us with an email address so we can reduce the amount of paper letters we need to send.
Year(s) Of Engagement Activity 2023
 
Description Newsletters to Airwave Health Monitoring Study participants 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact Jointly with our collaborators at DPUK, we sent a newsletter to all members of the cohort. This highlighted the recently completed research relating to Airwave usage, promoted the revised and expanded research objectives of the Tissue Bank, and provided a channel by which DPUK could explain how they are addressing their dementia-focussed research objectives and how their collaboration with the Airwave Tissue Bank may provide opportunities for joining research studies they are supporting.
Year(s) Of Engagement Activity 2019
 
Description Online training presentation for University of Warwick medical students on the REACT 2 COVID-19 study of keyworkers in Airwave cohort 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Online training session to introduce the REACT study and the health screening process to medical students at one of the selected field centres for the REACT 2 study in key workers prior to clinic go live date.
Year(s) Of Engagement Activity 2020
 
Description Oral presentation to 5th International Conference on Law Enforcement & Public Health LEPH2019, Edinburgh, Oct 2019 on Airwave Occupational Cohort Study 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited oral presentation to biennial national conference with aim of exploring and debating the intersections between law enforcement and public health involves. Audience included practitioners, policy makers and researchers from these and other related sectors. Aims of the study were presented and basic results and plans for future participant involvement. Opportunity to promote the study and engage with police and law enforcement agencies.
Year(s) Of Engagement Activity 2019
URL https://leph2019edinburgh.com/
 
Description Oral presentation to British APCO annual conference 13 March 2019 on Personal radio use and cancer risks among police officers and staff from the Airwave Health Monitoring Study 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited oral presentation by research team member to the British Association of Public Safety Communications Officials (BAPCO) annual meeting to present the aims of the study, how researchers are following up participant data and what the study has found in relation to risks of development of any diseases including cancers (ref: paper recently published in BJC). Airwave is investigating any effect of use of the TETRA radio technology on police officers and staff.
Year(s) Of Engagement Activity 2019
 
Description People Like you; Contemporary Figures of Personalisation - Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact People Like You' presented an online conversation about Stefanie Posavec's visualisation of the Airwave study and how work like hers can be useful for cohorts and biobanks.
As part of our Wellcome Trust Medical Humanities Collaborative award, "People Like You: contemporary figures of personalisation," Stefanie Posavec worked as an artist-in-residence exploring data science and personalisation through visualisation of the Airwave Health Monitoring Study.
As a part of this project, the People Like You team invited people who work with research cohorts and biobanks, people who participate in them, and people whose work focuses on these topics to hear a brief presentation of Stefanie's method, reactions from some of those who participated in her practice, and a Q&A discussion about how her work might be useful in other contexts. https://police-health.org.uk/news/stefanie-posavecs-visualisation-airwave-study
Year(s) Of Engagement Activity 2021
 
Description Presentation to 15th Annual Conference of The Metabolomics Society, The Hague, The Netherlands, June 23-27, 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presented methods and results of work on a metabolomics analysis to identify and characterise metabolomic signatures associated with risk variants for coronary artery disease using samples from MESA, Rotterdam and Airwave cohort studies with the aim of producing new knowledge on the causal pathways linking genes to CVD.
a new cross-cohort matching in untargeted metabolomics to generate accurate within-dataset feature matching across multiple cohorts.
Year(s) Of Engagement Activity 2019
URL http://metabolomics2019.org/images/2019-Metabolomics_Abstract_9.pdf