Unlocking potential: developing innovative adolescent screening visits for health promotion, prevention and treatment in low-resource settings

Lead Research Organisation: London School of Hygiene & Tropical Medicine
Department Name: Epidemiology and Population Health

Abstract

In adolescence, health-related behaviours are adopted that will have substantial positive or negative impacts on the individual's short- and long-term health, educational attainment, and employment prospects. However, in most low-income countries few adolescents have any contact with health services, especially for health promotion and disease prevention, and services are not always appropriate for their needs. Due to resource constraints there is often limited capacity to provide high-quality youth-friendly health services. Technological advances provide opportunities to deliver services and information away from traditional clinical settings, hence reducing barriers such as cost or confidentiality. Adolescents may be particularly receptive to digital platforms that allow them to self-manage their health and well-being.

What is A-CHECK? The programme will screen and treat/refer adolescents for common conditions through health check-ups in younger (10-13y) and older (16-19y) adolescents. Adolescents will only be screened for conditions with an accurate and acceptable test and a locally accessible effective intervention e.g. mental health, HIV, vision and hearing, anaemia.

What exactly will be done? I will develop, pilot-test, implement and evaluate the innovative A-CHECK programme and an accompanying digital platform in Zimbabwe. Check-up visits will take place at schools for younger and in the community for older adolescents. The platform will reduce the workload of staff by allowing adolescents to self-screen using questionnaires (e.g. mental health, risk behaviours) and pre-existing apps (to test hearing, eyesight, body composition), and will help the team to keep in touch with adolescents and provide information on referral appointments. I will analyse the data collected through the A-CHECK programme to improve its future acceptability and cost-effectiveness.

What are the main outcomes? Answers to the following questions - Do adolescents attend the screening and referral appointments? What impact do visits have on their health and education? How much does it cost for an adolescent to be screened and to obtain the recommended care for a condition? Is this a good value for money?

What is innovative about this study? The approach is innovative and novel, because, few LMICs currently provide check-up visits for adolescents and in countries where they are provided, the visits don't always meet the needs of adolescents e.g. don't include mental health screening. This proposal takes the innovative and bold step of moving from condition-specific health programmes towards an adolescent-centred approach focusing on what matters most to adolescents. This is the first empirical study to have investigated the effectiveness and cost-effectiveness of multi-component adolescent health check-ups. Specific innovations:
- Youth Researchers will participate in a human-centred design approach to intervention development
- Digital platform on which adolescents will complete some of the health screening activities, saving consultation time and improving the quality and efficiency of data collection
- Novel adolescent engagement activities including crowdsourcing contests and a reward system in the digital platform with adolescents gaining points when they complete screening and/or attend referral visits
- Machine learning and innovative data analysis to maximise A-CHECK efficiency and engagement by providing targeted messages and services

Why Zimbabwe? Zimbabwe is an ideal location for A-CHECK with great potential for scale-up given the close collaboration between BRTI and the Ministries of Health and Education, the emphasis on prevention within the 2018 School Health Policy, and the absence of other good ways to screen and refer adolescents. In other African settings, there is considerable interest in adolescent check-ups and potential for the Zimbabwean model to be adapted elsewhere.

Planned Impact

Youth: The immediate benefit of this research will be adolescents living in Harare and Chitungwiza cities in Zimbabwe who participate in this study. They will benefit from health screening, health services/referrals, and increased information on how to improve their health and well-being. If A-CHECK is not an appropriate way of delivering health services for adolescents, then there will be limited immediate benefit of this research. However, the knowledge gained during the project will inform the improvement of the content and/or the implementation of youth friendly health services in this area. The small number of adolescents and young people who participate in our Youth Advisory Group will gain an understanding of research, and may benefit from an increased sense of empowerment. If A-CHECK is effective and scaled-up in Zimbabwe and/or implemented in other LMICs, then many more adolescents will benefit from improved health and educational outcomes.

Families and the wider local community: Any benefit for adolescents in terms of improved health and well-being may benefit their partners and families by improving trust and/or engagement with healthcare services, and by improving overall well-being in the family. Short-term community-wide benefits would be minimal but if the intervention were to be implemented on a larger scale (based on the results of this work) then we would anticipate economic and societal impacts because of a more effective public health service, and improved health, prosperity, and quality of life for adolescents and their families.

Primary health care providers: This research will benefit primary health care providers by engaging with adolescents who are slipping through the net of existing preventive and treatment services. In the longer-term the use of a digital platform as a tool to facilitate more efficient screening, treatment and referral may reduce the workload of clinic staff and increase overall efficiencies in the health service.

Policy makers/programmers: This study is designed to inform practice, and we anticipate that the findings will be used to inform the design and implementation of adolescent check-up visits. If effective, check-up visits can be used as a strategy to achieve the goals of the 2018 School Health Policy. The findings e.g. on integration of services, self-screening etc. may also be transferrable to other population groups. In addition to data on the acceptability, feasibility and impact of the A-CHECK intervention, we will also be able to provide policy makers/programmers with data on the marginal cost of this approach. This intervention, if effective, would contribute to the international and national goal of universal healthcare.

International public health community: This research is aligned with relevant international and national commitments on improving the uptake of promotive, preventive and curative health care by adolescents, and by exploring the use of digital interventions within programmes. The results will be of interest to other regions and countries who are considering implementing digital interventions to improve adolescent health. The findings will feed directly into WHO guidelines on check-up visits for adolescents.

Academics & other collaborative staff: There is a paucity of research data on adolescents worldwide, as informed consent requirements often deter researchers from including those <18 years of age. This research will advance our understanding of the acceptability and feasibility of check-up visits and digital interventions for adolescents in LMICS, and the feasibility of engaging and interacting through a digital platform including through the use of self-screening questionnaires and screening apps. The A-CHECK team in Zimbabwe, and the LSHTM-based postdoc will have several capacity building opportunities including a significant on-the-job training and mentoring, and the opportunity to present at international conferences.

Publications

10 25 50
 
Description Y-Check is a multi-country research study which aims to develop, implement and evaluate an adolescent health and wellbeing check-up visit intervention. We conducted a pilot study in Chitungwiza, Zimbabwe which was led by The Health Research Unit Zim (THRU ZIM) at the Biomedical Research and Training Institute (BRTI) in collaboration with the London School of Hygiene & Tropical Medicine (LSHTM), the World Health Organization (WHO), Geneva, and partners. The pilot study took place over a period of six weeks between 6 June 22 and 16 July 22. The pilot intervention team comprised 1 youth champion, 2 research assistants, 2 nurses and 1 counsellor. The team delivered check-up visits to a total of 171 adolescents with the number of adolescents per day ranging from 3 to 19. Y-Check was delivered on 15 separate days during the pilot study period (7 days primary schools, 5 days secondary schools, and 3 days community hubs). The most prevalent clinical conditions detected were malnutrition (10%), visual impairment (8%), and anaemia (7%), and among older adolescents only, high blood pressure (13%). A high proportion of adolescents were flagged for psychosocial issues based on their response to the self-completed screening tool. In total 25/168 (14.8%) participants were referred to external service providers across all conditions.The success of the Y-Check pilot study was facilitated by good engagement with the pilot study schools. There was a high level of recruitment in the two primary schools. The Y-Check team were welcoming and youth-friendly which led to a good level of acceptance of the intervention among participants. The main challenges faced were low levels of parental consent at secondary schools, technical problems with the digital screening tool and screening algorithms, and challenges setting up and implementing referral pathways. Due to delays in acquiring the testing equipment and/or in engaging external experts to provide training, some conditions could not be screened for in the pilot study or were only included part-way through the pilot.
Following the pilot study, the protocol was amended to widen the eligible age range to include 14- year-olds in primary school and 15-year-olds in secondary schools and the community. Exit interviews were added along with the testing for and treatment of schistosomiasis haematobium. Procedural changes focused on reducing the length of the check-up visit and on making the screening tool and overall check-up visit more youth-friendly. An additional two-day pilot study was held in mid-October 2022 to further test and refine the procedures. The main Y-Check study started on the 19th October 2022 and will continue until the end of 2023. School and community engagement activities have been intensified to encourage higher levels of parental consent in the main study and to develop a supportive environment for healthy behaviours.
Exploitation Route The Y-Check pilot study showed the potential feasibility of delivering health and wellbeing check-up visits in urban Zimbabwe and identified areas for improvement of the intervention. The main implementation and evaluation is ongoing with initial findings from the main study expected in the second half of 2023.
Sectors Education,Healthcare

 
Description Presentation of Y-Check study at the WHO Meeting of the Strategic and Technical Advisory Group of Experts (STAGE) on Maternal, Newborn, Child, and Adolescent Health and Nutrition (MNCAHN)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a guidance/advisory committee
 
Description Bloomsbury PhD studentship
Amount £109,026 (GBP)
Organisation London School of Hygiene and Tropical Medicine (LSHTM) 
Sector Academic/University
Country United Kingdom
Start 09/2022 
End 08/2025
 
Description Y-Check: The Effectiveness and Cost-Effectiveness of Adolescent Health and Well-being Check-ups in Three African Cities
Amount $3,558,564 (USD)
Funding ID REG-21-001 
Organisation Fondation Botnar 
Sector Charity/Non Profit
Country Switzerland
Start 01/2022 
End 06/2024
 
Description Mwanza Intervention Trials Unit (MITU) 
Organisation National Institute for Medical Research, Tanzania
Department Mwanza Intervention Trials Unit (MITU)
Country Tanzania, United Republic of 
Sector Public 
PI Contribution MITU are a collaborator on the multi-country Y-Check study. We have provided technical support to the Tanzanian Y-Check study.
Collaborator Contribution MITU colleagues have provided technical support for the development of Y-Check Zimbabwe study protocol and procedures.
Impact MEMA kwa Vijana study publications. Y-Check study protocol and study tools. Joint investigator meeting in Harare, Zimbabwe in January 2023.
Start Year 2014
 
Description University of Ghana 
Organisation University of Ghana
Country Ghana 
Sector Academic/University 
PI Contribution University of Ghana are a collaborator on the WHO-led multi-country Y-Check study. We have provided technical support to the University of Ghana team.
Collaborator Contribution The University of Ghana team have provided technical advice on the development of Y-Check Zimbabwe study protocols and procedures.
Impact Study protocol and tools. Joint investigator meeting in Harare, Zimbabwe in January 2023
Start Year 2021
 
Description World Health Organization 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution The Y-Check Zimbabwe and LSHTM teams which I lead provide technical support to WHO who are leading the multi-country Y-Check study.
Collaborator Contribution WHO, Geneva are leading the multi-country Y-Check study. The Y-Check study in Zimbabwe, which I lead, is co-funded by UKRI and Fondation Botnar (through a grant to WHO). WHO provide technical support for the Y-Check studies.
Impact Study protocol and procedures.
Start Year 2021
 
Title Y-Check screening tool application 
Description The Y-Check screening tool app is being used in the Y-Check study in Zimbabwe to screen adolescents for health conditions and risk behaviours. The app facilitates data collection and the identification of adolescents who need further treatment, counselling and/or referral. 
Type Of Technology Webtool/Application 
Year Produced 2023 
Impact A demo of the application has been shared with collaborators planning Y-Check studies in Ghana and Tanzania and may be adapted for use in those settings. 
 
Description Zve Hutano Crowdsourcing competition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A crowdsourcing competition was held with young people living in a peri-urban area of Zimbabwe to to solicit new ideas, images or strategies from adolescents on how to brand and promote the Y-Check adolescent health and well-being check-up visit intervention. There were two categories (music and design). Participants, who are between the age of 10-19 years, submitted an entry of either a song or picture. Competition winners participated in a 'hackathon' to further develop the logo, messaging and song supported by a local music artist and a local design company. The competition increased the visibility of the new Y-Check competition and faciliated entry into the study communities.
Year(s) Of Engagement Activity 2021