Modelling the path to better soil-applied pesticides

Lead Research Organisation: University of York
Department Name: Environment

Abstract

Many pesticides are soil applied, including residual herbicides, soil insecticides and seed treatments incorporating fungicides and/or insecticides. They are under intense regulatory pressure with regard to water contamination, and continue to be lost from the market as a result. Simulation models are the primary basis for regulating pesticides against EU ground- and surface-water protection standards. Since these models are one-dimensional, they cannot explicitly represent plants or their roots, or the effects of formulations and formulation placement strategies. Other models exist that represent individual components of the system is a more satisfactory way. This project will create a conceptual framework for representing local pesticide concentrations in the whole soil-plant system, and will use it to produce a spatially-competent simulation model, that integrates existing knowledge. Advanced formulations and placement strategies offer the prospect of reduced off-target movement. The new model will for the first time enable their environmental benefit to be quantified in a cost-effective way. This offers the prospect of being able to gain credit in the regulatory approval process for these technologies, offsetting the negative economic effects of evolving regulation. In combination with existing empirical approaches, the new model will also deliver quantitative understanding of pesticide efficacy in the soil-plant system, enabling the rational design of new active ingredients and formulations. In short, the project will enable efficacy and environmental protection to be optimised for soil-applied pesticidal products, aiding product invention and supporting regulatory approval.This project is well aligned to the competition scope. The results will enable the optimisation of efficacy and water protection at the product design stage, leading to more efficacious products that enhance crop productivity and reduce environmental impact. The project also creates a way to demonstrate the environmental benefit of advanced formulation technology and product placement strategies, and offers the prospect of gaining credit for these in the EU regulatory review process for pesticides, in which great weight is placed on pesticide fate models. Formulations and placement strategies that significantly reduce water contamination would also fit naturally into regulatory mitigation strategies, and risk management schemes at the field and watershed level.

Publications

10 25 50
 
Description The project addresseds two main business opportunities identified by the agrochemicals company Sygnenta: (i) to enable the rational design of more efficacious soil-applied pesticides, and (ii) to gain/retain market access for pesticide uses for which regulatory approval would otherwise not be possible. The project developed a spatially-explicit model of pesticide fate in the soil-plant system and losses to water, that is able to meet these identified needs. The developed model is called PESTER. For further details, see entry by the project team at Rothamsted Research led by Dr Andy Whitmore.
Exploitation Route The PESTER model is already in use within Syngenta's pesticide development and registration business. Dissemination has taken place to other potential users including the UK Chemicals Regulation Directorate. For further details, see entry by the project team at Rothamsted Research led by Dr Andy Whitmore.
Sectors Agriculture, Food and Drink,Chemicals

 
Description The model has been taken up within Sygenta's product development and registration business. The use is to enable the rational design of more efficacious soil-applied pesticides, and to gain/retain market access for pesticide uses for which regulatory approval would otherwise not be possible. Syngenta are intending to use the model to support regulatory submissions and several presentations have been given at international symposia as well as a dedicated workshop (24/09/2013) to communicate the science base and support uptake by the regulatory community. The PESTER model also forms the basis for ongoing collaborative research with Brown, York (PI) and Sweeney, Syngenta (CoI) and funded by TSB/BBSRC (13TSB_ACT). This follow-on project seeks to couple spatially-explicit modelling for the soil-crop continuum with individual-based modelling for the target pest and toxicokinetic/toxicodynamic modelling to provide Syngenta with bespoke software to guide the discovery and design of new pesticidal products.
First Year Of Impact 2013
Sector Agriculture, Food and Drink,Chemicals
Impact Types Economic

 
Title PESTER 
Description Mathematical model that explicitly predicts fate of pesticides in soil within two dimensions. The model combines existing hydrological methods (CHAIN-2D) and a spatially-explicit of description of root development (SPACSYS) and incorporates pesticide fate. TSB/EPSRC funding aimed at delivering the PESTER model into Syngenta's business as well as disseminating the underlying science to key stakeholders within the pesticide regulatory community. The model is used to primarily to simulate the effect of targeted pesticide formulations, including seed treatments, on the environmental behaviour of pesticides. No URL is provided below because the model IP is used commercially by Syngenta with IP held by Rothamsted Research. 
Type Of Material Computer model/algorithm 
Year Produced 2013 
Provided To Others? Yes  
Impact The model is in use to support design and registration of pesticides within Syngenta.