Relationship between synaptic dysfunction and degeneration in a rodent model of dementia

Lead Research Organisation: University of Exeter
Department Name: University of Exeter Medical School

Abstract

Synaptic dysfunction plays a key role in the cognitive decline seen in dementias such as Alzheimers Disease. This PhD projkect will examine the function of individual synapses in a mouse model of dementia, using whole-cell electrophysiology and in vivo two-photon imaging techniques.

Publications

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/N013794/1 01/10/2016 30/09/2025
1789782 Studentship MR/N013794/1 01/10/2016 30/09/2020 Soraya Meftah
 
Description MRC Flexible Funding for Placement
Amount £2,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 12/2017 
End 12/2017
 
Description Pump Priming Award for Equipment
Amount £3,500 (GBP)
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2017 
End 07/2017
 
Description Travel Grant for BNA Conference
Amount £200 (GBP)
Organisation British Neuroscience Association 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2019 
End 04/2019
 
Description UK National Productivity Investment Fund Via MRC for placement in industry
Amount £7,300 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 03/2019 
End 03/2020
 
Description Brain Awareness Week Organizer and Speaker. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact School visit of over 40 students to engage with hands on lab practicals.
Public seminar to over 100 people a night (1 night in 2018, 2 in 2019).
Local open day where we had a stand.
Speed networking event (20 people approx).
Year(s) Of Engagement Activity 2018,2019
 
Description Pint of Science - Our Bodies - Event Organiser 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Event over 3 nights with different speakers discussing their research in a lay way.
Year(s) Of Engagement Activity 2017
 
Description Speaker at Soapbox Science - Exeter 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Standing on a podium in the streets spending an hour talking about my research to the general public. People could attend and pass by and engage as they wanted.
Also wrote a blog post to help advertise this further.
Year(s) Of Engagement Activity 2018