The Impact of Parental Mental Health on Offspring Development
Lead Research Organisation:
King's College London
Department Name: Social Genetic and Dev Psychiatry Centre
Abstract
This project will be centred on the genetically informed investigation of the intergenerational transmissionof psychopathology. It will involve the use of multiple, large, family -
based datasets to distinguish potentially true, environmentally mediated associations between parent and child psychopathology, from genetic transmission.
based datasets to distinguish potentially true, environmentally mediated associations between parent and child psychopathology, from genetic transmission.
People |
ORCID iD |
| Thomas McAdams (Primary Supervisor) | |
| Daniel Wechsler (Student) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/N013700/1 | 01/10/2016 | 30/09/2025 | |||
| 1935754 | Studentship | MR/N013700/1 | 01/10/2017 | 31/07/2022 | Daniel Wechsler |
| Description | Collaboration with the Early Growth and Development Study (EGDS) |
| Organisation | Penn State University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Myself and my supervisors planned a longitudinal adoption-at-birth study using data provided by the EGDS team in the US, and I've run the analyses and have written up a manuscript of the results for the EGDS team to review. |
| Collaborator Contribution | They provided the data and assisted with any data issues as well as reviewing and approving the project plan. They have since reviewed results and are currently reviewing my final manuscript. They also reviewed a an academic poster I presented at the ICPS 2019 conference in Paris. |
| Impact | Academic poster presented at the ICPS 2019 Conferece - Title: A Longitudinal, Genetically Sensitive Investigation of Childhood ADHD and Comorbid Disorder Symptoms in the Context of Parenting. The study falls under the discipline of behavioural genetics, which is inherently interdisciplinary as it combines conventional developmental research tracking the influence of environmental factors on child development, with data on the genetic relationships between children and parents, which allows the analyses to account for genetic confounding. |
| Start Year | 2017 |
| Description | Collaboration with the Early Growth and Development Study (EGDS) |
| Organisation | University of Oregon |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Myself and my supervisors planned a longitudinal adoption-at-birth study using data provided by the EGDS team in the US, and I've run the analyses and have written up a manuscript of the results for the EGDS team to review. |
| Collaborator Contribution | They provided the data and assisted with any data issues as well as reviewing and approving the project plan. They have since reviewed results and are currently reviewing my final manuscript. They also reviewed a an academic poster I presented at the ICPS 2019 conference in Paris. |
| Impact | Academic poster presented at the ICPS 2019 Conferece - Title: A Longitudinal, Genetically Sensitive Investigation of Childhood ADHD and Comorbid Disorder Symptoms in the Context of Parenting. The study falls under the discipline of behavioural genetics, which is inherently interdisciplinary as it combines conventional developmental research tracking the influence of environmental factors on child development, with data on the genetic relationships between children and parents, which allows the analyses to account for genetic confounding. |
| Start Year | 2017 |
| Description | The Intergenerational Transmission of Risk (IToR) study |
| Organisation | University of Oslo |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Myself and my supervisors have planned a longitudinal Multiple-Children-of-Twins-and-Siblings (MCoTS) study using data from the Mother and Child Cohort Study (MoBa), a national registry of over 110,000 children, 90,000 of their mothers and 75,000 of their fathers in Norway. I then ran the analyses and am currently writing up a manuscript. |
| Collaborator Contribution | Our collaborators at the University of Oslo assisted with our project plan, and have done a lot of the data preparation necessary for us to be able to conduct these complex analyses. They will also review my manuscript once it is finished. |
| Impact | None so far. |
| Start Year | 2018 |