Investigating the function and regulation of PDCD4 in B cell neoplasms

Lead Research Organisation: University of Southampton
Department Name: Cancer Sciences

Abstract

Investigate PDCD4 regulation in B cell lymphoma cell lines and primary chronic lymphocytic leukemia (CLL) cells. This will involve treatment with inhibitors of BCR signalling and translation machinery to investigate the role of PDCD4 in malignancy. Focus will be on investigating the post-translational modification of PDCD4 and the transcriptional regulation of PDCD4 using a bioinformatics approach.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/N014308/1 01/10/2016 30/09/2025
1943791 Studentship MR/N014308/1 01/10/2017 31/12/2021 Joe Taylor