Genetic risk factors involved in brain circuit changes caused by early life adversity
Lead Research Organisation:
University of Bristol
Department Name: Physiology and Pharmacology
Abstract
Stressful experiences caused by early life adversity are highly significant in determining a child's future susceptibility to a range of psychiatric disorders including anxiety and depression. This project aims to investigate genetic factors that may influence this susceptibility and the brain circuits perturbed by these events.
People |
ORCID iD |
| Jack Mellor (Primary Supervisor) | |
| Simonas Griesius (Student) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/N013794/1 | 01/10/2016 | 30/09/2025 | |||
| 1952898 | Studentship | MR/N013794/1 | 01/10/2017 | 30/09/2021 | Simonas Griesius |
| Description | Genetic models of psychiatric disorders |
| Organisation | Cardiff University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Electrophysiological and behavioural analyses of genetically modified animals |
| Collaborator Contribution | Genetics expertise and animal models. Complementary behavioural analyses. |
| Impact | no outputs as yet. Multidisciplinary collaboration including genetics, rodent behaviour, electrophysiology, imaging |
| Start Year | 2018 |
| Description | Press release |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Press releases about our published research (Neuron 2010 and J Neurosci 2011, Nature Neurosci 2012, Cerebral Cortex 2016 and Nature Communications 2016) led to interest from a number of media outlets. Article on our reserach published in New Scientist. |
| Year(s) Of Engagement Activity | 2010,2011,2013,2015,2016,2017,2018,2019,2020,2021 |