Understanding the resistance landscape to gene drives targeting ultra-conserved regions in the doublesex gene of Anopheles gambiae
Lead Research Organisation:
Imperial College London
Department Name: Life Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
People |
ORCID iD |
| Andrea Crisanti (Primary Supervisor) | |
| Ioanna MORIANOU (Student) |
Publications
Garrood WT
(2021)
Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito.
in Proceedings of the National Academy of Sciences of the United States of America
Hammond A
(2021)
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field.
in Nature communications
Hammond A
(2021)
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance.
in PLoS genetics
Morianou I
(2022)
CRISPR-Mediated Cassette Exchange (CriMCE): A Method to Introduce and Isolate Precise Marker-Less Edits.
in The CRISPR journal
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/N014103/1 | 30/09/2016 | 30/03/2026 | |||
| 1961745 | Studentship | MR/N014103/1 | 29/09/2017 | 29/06/2022 | Ioanna MORIANOU |
| NE/W503198/1 | 31/03/2021 | 30/03/2022 | |||
| 1961745 | Studentship | NE/W503198/1 | 29/09/2017 | 29/06/2022 | Ioanna MORIANOU |
| Description | Exhibition Road Festival |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Showcasing our lab's work on gene drives as a method of genetic control of the malaria mosquito vector. Reaching out to different members of the public, both kids and grown-ups. Engaging in scientific conversations and answering any questions the public might have on the technologies we develop and the wider scope of our project. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.greatexhibitionroadfestival.co.uk/ |